solutions
1. What are 7. What are the in- dications of ri-
the varoxaban?
indications
of 8. What is the MOA of rivaroxaban?
metoprolol
?
2. What is the
MoA of
metoprolol?
3. What are the
black box
warn- ings of
metopro- lol?
4. What are the
drug
interactions of
metoprolol?
5. What are the
AEs of
metoprolol?
6. What are
mon- itoring
parame- ters
of metopro-
lol?
,Pharmacotherapy 1 Exam 1 questions with complete
solutions
Angina, heart failure, arrest), antidiabetic drugs (decreased glycemic control), CCB/quinidine
hypertension, AMI (hypotension/bradycardia/av block), clonidine (exagerrated with- drawal
response), NSAIDs/venlafaxine (decreased antihypertensive ettect)
Dizziness, fatigue, hypotension, heart failure
Cardio selective beta blocker
Signs symptoms of heart failure, monitor serum electrolytes and renal
Avoid abrupt withdrawal function, monitor blood sugar in diabetic patients
Prevention of thromboembolism in patients after orthopedic surgery,
Alpha blockers/fentanyl prevention of thromboembolism in patients with nonvalvular a fib,
(hypotension), amiodarone treatment and secondary prevention of DVT or PE
(increased risk of bradycar-
dia/heart block/sinus Orally bioavailable factor Xa inhibitor, selectively blocks active site of facto
Xa
9.
,Pharmacotherapy 1 Exam 1 questions with complete
solutions
What are the 15. What is the MoA of spirono- lactone?
blackbox
warn- ings of 16. What are the blackbox warn- ings of
rivaroxa- ban? spirono- lactone?
10. What are the
drug
interactions of
rivaroxaban?
11. What are the
AEs of
rivaroxaban?
12. What are
the
monitoring
pa-
rameters of
ri-
varoxaban?
13. What type of
drug is
spirono-
lactone?
14. What are the
indications of
spironolacton
e?
,Pharmacotherapy 1 Exam 1 questions with complete
solutions
ature discontinuation increases for bleeding, take with evening meal, should be taken with food
thrombotic risk, risk of
spinal/epidural hematoma
potassium sparing diuretic
atelet
agents/NSAIDs/anticoagulants
(additive risk of bleeding) Heart failure 3-4, edema associated with heart failure, nephrotic syndrome, hy-
pertension, hypokalemia
ing, syncope, major bleeding, Aldosterone antagonist
epidural hematoma, anaphylaxis,
intracranial bleeding
have to monitor Tumorigenic in animal models
anticoagulation tests, watch