D441 Pharmacology study
Medical Dosage Calculations and Pharmacology (Western Governors University)
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Digoxin
Used for heart failure.
S/S: GI upset, anorexia, vision changes
Nursing considerations:
- Check apical pulse, <60 BPM = hold medication
- Monitor potassium (low k+ increases risk for toxicity)
- Draw digoxin levels (normal 0.5-2) OVER 2 IS TOXIC
If toxin occurs:
- Hold medication and notify HCP
- Admin digoxin immune fab (If ordered)
- Treat electrolytes imbalances (hypokalemia)
- Continuous cardiac monitoring
Patient teaching:
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- Take at the same time daily; do not skip or double doses
Lithium
Used as a mood stabilizer for bipolar disorder
S/S: coarse tremors, confusion, hypotension, seizures, tinnitus
Nursing considerations:
- Monitor lithium levels (therapeutic range 0.6-1.2; OVER 1.5 IS TOXIC)
- Monitor sodium, BUN, creatinine
- Ensure adequate sodium & fluid intake
If toxin occurs:
- Hold medication; notify HCP
- Prepare for possible gastric lavage or hemodialysis
- Support airway and cardiovascular function
Patient teaching:
- Maintain consistent salt & fluid intake
- Avoid dehydration and excessive sweating
- Take with food to avoid GI upset
Heparin/Enoxaparin
Used for IV/Subcutaneous anticoagulant
S/S: low platelets, bleeding, bruising, spinal/epidural hematoma
Nursing considerations:
- Monitor aPTT (normal 65-105 seconds)
- Access for bleeding (gums, urine, stool)
If toxin occurs:
- Stop infusion immediately
- Administer protamine sulfate (antidote)
- Apply pressure to bleeding site
Patient teaching:
- Use a soft bristle toothbrush, electric razor
- No NSAIDs or Aspirin
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