46
Chapter 07: Immunity
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th
Edition
MULTIPLE CHOICE
1. Neutrophils
a. are phagocytic cells.
b. produce histamine.
c. produce antibodies.
d. are elevated during an allergic response.
ANS> A
2. Which cells are required to process and present antigens from foreign material as the initial
step in the immune response?
a. T-helper cells
b. Macrophages
c. Eosinophils
d. Monocytes
ANS> B
3. Humoral immunity is mediated by
a. natural killer cells.
b. T lymphocytes (T cells).
c. B lymphocytes (B cells).
d. neutrophils.
ANS> C
4. A secondary immune response differs from the primary immune response in that
a. it is more rapid than the primary response and results in higher antibody levels.
b. it is slower than the primary response and doesn’t change the antibody levels.
c. it occurs at the same time as the primary response but results in a decrease in
antibodies.
d. it only occurs in hyperallergic reactions and results in a decrease of antibodies.
ANS> A
5. Which type of immunity is provided by a vaccination?
a. Active natural
b. Active artificial
c. Passive natural
d. Passive artificial
ANS> B
6. When an allergen binds with IgE antibodies on mast cells, resulting in release of chemical
mediators, this reaction is called
a. cytotoxic hypersensitivity.
, 47
b. immune complex hypersensitivity.
c. type I hypersensitivity.
d. type IV hypersensitivity.
ANS> C
7. The role of memory cells is to
a. change into an antibody-secreting cell following activation.
b. immediately secrete antibodies following the first exposure to antigen.
c. recognize the antigen and stimulate the immune response.
d. bind complement to the antibody.
ANS> C
8. Which statement applies to contact dermatitis?
a. It occurs when IgE antibodies on the skin react with the causative substance.
b. It may result from ingested foods.
c. Urticaria (hives) gradually spread over the body.
d. A type IV reaction occurs in affected areas.
ANS> D
9. Which of the following causes anaphylaxis?
a. A severe, systemic allergic reaction
b. Type III hypersensitivity
c. Cell-mediated hypersensitivity
d. Immune complex deposits in many tissues
ANS> A
10. Following a positive HIV antibodies blood test and ELISA test, what is the test commonly
used for confirmation?
a. Agglutination
b. Double immunodiffusion test
c. Western blot test
d. Sedimentation rate test
ANS> C
11. Incompatible blood transfusions result in
a. hemolysis of erythrocytes.
b. a type I immune response.
c. deposits in multiple organs.
d. immune deficiency.
ANS> A
12. An autoimmune disease is
a. excessive formation of antibodies following exposure to foreign material.
b. an extreme response to normally harmless material in the environment.
c. an abnormal response to ingested food and drugs.
d. failure of the immune system to distinguish self from nonself.
, 48
ANS> D
13. Systemic lupus erythematosus is caused by
a. a chronic allergic condition.
b. development of an immune-deficient state.
c. a deficiency of T lymphocytes.
d. immune complex deposits of antinuclear antibodies.
ANS> D
14. Distinguishing clinical features of systemic lupus erythematosus include
a. inflammation in multiple organs.
b. lack of a specific diagnostic blood test.
c. acute onset and nonprogressive course.
d. typical skin rash on the chest and back.
ANS> A
15. Which of the following are the target cells for HIV?
a. Helper T lymphocytes (CD4 lymphocytes)
b. B lymphocytes
c. Natural killer cells
d. Macrophages
ANS> A
16. A diagnosis of HIV positive means that
a. the number of T lymphocytes in the circulating blood is decreased.
b. significant opportunistic infection is present in the body.
c. the individual has AIDS.
d. the virus and its antibodies are present in the blood.
ANS> D
17. HIV infection impairs
a. humoral immunity.
b. cell-mediated immunity.
c. both humoral and cell-mediated immunity.
d. neither type of immunity.
ANS> C
18. Immunodeficiencies may result in an increased risk of infections by normally harmless
microorganisms. These infections are referred to as
a. opportunistic.
b. prophylactic.
c. abnormal.
d. transient.
ANS> A
19. Serious infections frequently occurring in patients with AIDS include
1. tuberculosis.
Chapter 07: Immunity
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th
Edition
MULTIPLE CHOICE
1. Neutrophils
a. are phagocytic cells.
b. produce histamine.
c. produce antibodies.
d. are elevated during an allergic response.
ANS> A
2. Which cells are required to process and present antigens from foreign material as the initial
step in the immune response?
a. T-helper cells
b. Macrophages
c. Eosinophils
d. Monocytes
ANS> B
3. Humoral immunity is mediated by
a. natural killer cells.
b. T lymphocytes (T cells).
c. B lymphocytes (B cells).
d. neutrophils.
ANS> C
4. A secondary immune response differs from the primary immune response in that
a. it is more rapid than the primary response and results in higher antibody levels.
b. it is slower than the primary response and doesn’t change the antibody levels.
c. it occurs at the same time as the primary response but results in a decrease in
antibodies.
d. it only occurs in hyperallergic reactions and results in a decrease of antibodies.
ANS> A
5. Which type of immunity is provided by a vaccination?
a. Active natural
b. Active artificial
c. Passive natural
d. Passive artificial
ANS> B
6. When an allergen binds with IgE antibodies on mast cells, resulting in release of chemical
mediators, this reaction is called
a. cytotoxic hypersensitivity.
, 47
b. immune complex hypersensitivity.
c. type I hypersensitivity.
d. type IV hypersensitivity.
ANS> C
7. The role of memory cells is to
a. change into an antibody-secreting cell following activation.
b. immediately secrete antibodies following the first exposure to antigen.
c. recognize the antigen and stimulate the immune response.
d. bind complement to the antibody.
ANS> C
8. Which statement applies to contact dermatitis?
a. It occurs when IgE antibodies on the skin react with the causative substance.
b. It may result from ingested foods.
c. Urticaria (hives) gradually spread over the body.
d. A type IV reaction occurs in affected areas.
ANS> D
9. Which of the following causes anaphylaxis?
a. A severe, systemic allergic reaction
b. Type III hypersensitivity
c. Cell-mediated hypersensitivity
d. Immune complex deposits in many tissues
ANS> A
10. Following a positive HIV antibodies blood test and ELISA test, what is the test commonly
used for confirmation?
a. Agglutination
b. Double immunodiffusion test
c. Western blot test
d. Sedimentation rate test
ANS> C
11. Incompatible blood transfusions result in
a. hemolysis of erythrocytes.
b. a type I immune response.
c. deposits in multiple organs.
d. immune deficiency.
ANS> A
12. An autoimmune disease is
a. excessive formation of antibodies following exposure to foreign material.
b. an extreme response to normally harmless material in the environment.
c. an abnormal response to ingested food and drugs.
d. failure of the immune system to distinguish self from nonself.
, 48
ANS> D
13. Systemic lupus erythematosus is caused by
a. a chronic allergic condition.
b. development of an immune-deficient state.
c. a deficiency of T lymphocytes.
d. immune complex deposits of antinuclear antibodies.
ANS> D
14. Distinguishing clinical features of systemic lupus erythematosus include
a. inflammation in multiple organs.
b. lack of a specific diagnostic blood test.
c. acute onset and nonprogressive course.
d. typical skin rash on the chest and back.
ANS> A
15. Which of the following are the target cells for HIV?
a. Helper T lymphocytes (CD4 lymphocytes)
b. B lymphocytes
c. Natural killer cells
d. Macrophages
ANS> A
16. A diagnosis of HIV positive means that
a. the number of T lymphocytes in the circulating blood is decreased.
b. significant opportunistic infection is present in the body.
c. the individual has AIDS.
d. the virus and its antibodies are present in the blood.
ANS> D
17. HIV infection impairs
a. humoral immunity.
b. cell-mediated immunity.
c. both humoral and cell-mediated immunity.
d. neither type of immunity.
ANS> C
18. Immunodeficiencies may result in an increased risk of infections by normally harmless
microorganisms. These infections are referred to as
a. opportunistic.
b. prophylactic.
c. abnormal.
d. transient.
ANS> A
19. Serious infections frequently occurring in patients with AIDS include
1. tuberculosis.
