CSO EXAM: INTERACTIONS WITH CANCER MEDICATIONS WITH QUESTIONS AND ANSWERS 100% VERIFIED

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CSO EXAM: INTERACTIONS WITH CANCER
MEDICATIONS WITH QUESTIONS AND
ANSWERS 100% VERIFIED



Temozolomide - correct answer_ Temodar
oral: take at bedtime or on an empty stomach w/full glass of water


-do not crush or dissolve drug




Thalidomide - correct answer_ Thalomid
Oral: take at bed time, at least 1 hour after evening meal


-drug interactions w/barbiturates, chlorpromazine, reserpine and
alcohol




Vinblastine - correct answer_ Velban
IV

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-avoid CYP3A4 inducers which may decrease drug activity (St. John's
wort, phenobarbital, dexamethasone)
-avoid CYP3A4 inhibitors which may increase drug activity(grapefruit
juice, ketoconazole and erythromycin)
-stool softeners and/or stimulant laxative may help prevent severe
constipation




Vincristine - correct answer_ Oncovin
IV


-avoid CYP3A4 inducers which may decrease drug activity (St. John's
wort, phenobarbital, dexamethasone)
-avoid CYP3A4 inhibitors which may increase drug activity(grapefruit
juice, ketoconazole and erythromycin)
-stool softeners and/or stimulant laxative may help prevent severe
constipation




Zoledronic acid - correct answer_ Zometa
IV


patients should take an oral supplement of 500mg Ca and 400IU
VItamin D daily