Reproductive-FA exam
2. 636
Embryology
genes involoved in embryogenesis 4: Sonic hedgehog (SHH) gene
Wnt-7 gene
Fibroblast growth factor (FGF) gene
Homeobox (Hox) genes
3. site and function of the genes 4
SHH
-site
-action 2
-mutation
,Wnt 7 gene
-site
-action
FGF gene
-site
-action
hox gene
-site
-action
-mutation result
eg: Sonic hedgehog (SHH) gene
,-base of limbs
-ant/pos axis,CNS dev
-holoprosencephaly
Wnt-7 gene
-distal end of limbs
, -dorsal/ventral axis
Fibroblast growth factor (FGF) gene
-apical ectodermal ridge
-limb lengthening
Homeobox (Hox) genes
-multiple
-craniocaudal segmental development
-appendages in wrong sites
-isotretinoine>increase hox gene expression
4. embryogenesis
-week 1-secretes,result
-week 2,layers
-week 3,layers,
mesoderm formed how,through
how is neural plate formed
2. 636
Embryology
genes involoved in embryogenesis 4: Sonic hedgehog (SHH) gene
Wnt-7 gene
Fibroblast growth factor (FGF) gene
Homeobox (Hox) genes
3. site and function of the genes 4
SHH
-site
-action 2
-mutation
,Wnt 7 gene
-site
-action
FGF gene
-site
-action
hox gene
-site
-action
-mutation result
eg: Sonic hedgehog (SHH) gene
,-base of limbs
-ant/pos axis,CNS dev
-holoprosencephaly
Wnt-7 gene
-distal end of limbs
, -dorsal/ventral axis
Fibroblast growth factor (FGF) gene
-apical ectodermal ridge
-limb lengthening
Homeobox (Hox) genes
-multiple
-craniocaudal segmental development
-appendages in wrong sites
-isotretinoine>increase hox gene expression
4. embryogenesis
-week 1-secretes,result
-week 2,layers
-week 3,layers,
mesoderm formed how,through
how is neural plate formed