PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
Helper T cells associate with which class of MHC molecules?
MHC Class 2 (extracellular infection)
BCR (B cell receptor) and TCR (T cell receptor), how are they created and where in the body are
they created?
As a result of Gene Arrangement (VDJ Somatic Recombination).
- BCR: produced in Bone Marrow
- TCR: produced in Thymus
Interferon function
Viral fighting, they activate NK cells which then tell our infected cells to die by apoptosis.
BCR and TCR how are they created?
somatic recombination - gene rearrangement = sequence variability in V regions (bone marrow
vs. thymus)
What process creates the variable region domain for both TCRs and BCRs?
Somatic Recombination
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
Structure of immunoglobulin and the T cell receptor (TCR)?
Ig:
- Ig = Heavy and light chains, Fab and Fc regions, 4 polypeptide chains, secreted.
TCR:
- (alpha) chain and (beta) chain each with variability and constant region.
- TCR = α and β chains, 2 polypeptide chains, CD3 complex (4 proteins for signaling), 2 zeta
chains, transmembrane.
Each chain has a variable and a constant region
What the different types IFN-1?
Alpha and Beta
structure of immunoglobulin and the TCR
a. BCR: 4 polypeptide chain with a and b for signalling on the surface of a B cell
b. Domain structure of TCR is similar to lg
c. TCR: 2 polypeptide, CD3 complex (4 proteins for signaling), and 2 zeta chains
d. each chain has variable region and constant region
What are the differences and similarities between CD8 T Cells and NK cells?
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
The both have the same cytotoxic granules, NK cells are activated faster, because they come out
of the bone marrow "ready to go". CD8 T cells recognizes MHC Class 1 + peptide (antigen) on a
pathogen, while NK cells recognize normal MHC Class 1 molecules on the surface of our cells
and activating ligands that infected cells put up on their surface.
The T cell receptor (TCR) type of antigen vs. Ig (BCR) type of antigen?
a) TCR
TCR:
- bind to peptide antigens which are derived from the pathogen's proteins.
- It requires presentation by MHC molecules.
- Cells bind one type of antigen which must be presented to them on the surface of another
human cell.
2 types of activating ligands
MIC - A and MIC - B, they bind to activating receptors on activating NK cells
The TCR type of antigen vs. lg type of antigen.
a. TCR only found on the surface of their t cells; multipoint attachement; multiple copies of TCR
bind to multiple copies of antigen (MHC complex on opposing cell)
b. BCR can be secreted in the form of an antibody; bind epitopes on intact molecules
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
Type 2 interferon
Also know as IFN- gamma, activates macrophages
The T cell receptor (TCR) type of antigen vs. Ig (BCR) type of antigen?
b) BCR
BCR:
- bind intact molecules and DO NOT require presentation.
- bind to proteins/carbohydrates/lipids on the surfaces of pathogens.
IL - 12
Inflammatory cytokine that activates NK cells which then produces IFN - gamma which then
activate macrophages.
Function of a TCR.
a. used only to recognize antigens
b. TCR membrane bound glycoprotein: recognize cell-to-cell contact.
Which complement receptors can recognize C3b?
CR 1 - CR 4
Update) Review| Questions & Answers
|100% verified | Grade A
Helper T cells associate with which class of MHC molecules?
MHC Class 2 (extracellular infection)
BCR (B cell receptor) and TCR (T cell receptor), how are they created and where in the body are
they created?
As a result of Gene Arrangement (VDJ Somatic Recombination).
- BCR: produced in Bone Marrow
- TCR: produced in Thymus
Interferon function
Viral fighting, they activate NK cells which then tell our infected cells to die by apoptosis.
BCR and TCR how are they created?
somatic recombination - gene rearrangement = sequence variability in V regions (bone marrow
vs. thymus)
What process creates the variable region domain for both TCRs and BCRs?
Somatic Recombination
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
Structure of immunoglobulin and the T cell receptor (TCR)?
Ig:
- Ig = Heavy and light chains, Fab and Fc regions, 4 polypeptide chains, secreted.
TCR:
- (alpha) chain and (beta) chain each with variability and constant region.
- TCR = α and β chains, 2 polypeptide chains, CD3 complex (4 proteins for signaling), 2 zeta
chains, transmembrane.
Each chain has a variable and a constant region
What the different types IFN-1?
Alpha and Beta
structure of immunoglobulin and the TCR
a. BCR: 4 polypeptide chain with a and b for signalling on the surface of a B cell
b. Domain structure of TCR is similar to lg
c. TCR: 2 polypeptide, CD3 complex (4 proteins for signaling), and 2 zeta chains
d. each chain has variable region and constant region
What are the differences and similarities between CD8 T Cells and NK cells?
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
The both have the same cytotoxic granules, NK cells are activated faster, because they come out
of the bone marrow "ready to go". CD8 T cells recognizes MHC Class 1 + peptide (antigen) on a
pathogen, while NK cells recognize normal MHC Class 1 molecules on the surface of our cells
and activating ligands that infected cells put up on their surface.
The T cell receptor (TCR) type of antigen vs. Ig (BCR) type of antigen?
a) TCR
TCR:
- bind to peptide antigens which are derived from the pathogen's proteins.
- It requires presentation by MHC molecules.
- Cells bind one type of antigen which must be presented to them on the surface of another
human cell.
2 types of activating ligands
MIC - A and MIC - B, they bind to activating receptors on activating NK cells
The TCR type of antigen vs. lg type of antigen.
a. TCR only found on the surface of their t cells; multipoint attachement; multiple copies of TCR
bind to multiple copies of antigen (MHC complex on opposing cell)
b. BCR can be secreted in the form of an antibody; bind epitopes on intact molecules
, PCB 3233 Exam 3 (Latest 2026/ 2027
Update) Review| Questions & Answers
|100% verified | Grade A
Type 2 interferon
Also know as IFN- gamma, activates macrophages
The T cell receptor (TCR) type of antigen vs. Ig (BCR) type of antigen?
b) BCR
BCR:
- bind intact molecules and DO NOT require presentation.
- bind to proteins/carbohydrates/lipids on the surfaces of pathogens.
IL - 12
Inflammatory cytokine that activates NK cells which then produces IFN - gamma which then
activate macrophages.
Function of a TCR.
a. used only to recognize antigens
b. TCR membrane bound glycoprotein: recognize cell-to-cell contact.
Which complement receptors can recognize C3b?
CR 1 - CR 4
