NURS 3366 - Pathophysiology: Exam 3
|\ |\ |\ |\ |\ |\
Review questions with answers |\ |\ |\
What is the initiating event that leads to the development
|\ |\ |\ |\ |\ |\ |\ |\ |\
of atherosclerosis?
|\ |\ |\
a. Release of the inflammatory cytokines
|\ |\ |\ |\ |\
b. Macrophages adhere to vessel walls.
|\ |\ |\ |\ |\
c. Injury to the endothelial cells that line the artery walls
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
d. Release of the platelet-deprived growth factor
|\ |\ |\ |\ |\ |\
c. Injury to the endothelial cells that line the artery walls
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
What is the effect of oxidized low-density lipoproteins
|\ |\ |\ |\ |\ |\ |\ |\
(LDLs) in atherosclerosis?
|\ |\ |\
a. LDLs cause smooth muscle proliferation.
|\ |\ |\ |\ |\
b. LDLs cause regression of atherosclerotic plaques.
|\ |\ |\ |\ |\ |\
c. LDLs increase levels of inflammatory cytokines.
|\ |\ |\ |\ |\ |\
d. LDLs direct macrophages to the site in the endothelium.
|\ |\ |\ |\ |\ |\ |\ |\ |\
a. LDLs cause smooth muscle proliferation.
|\ |\ |\ |\ |\
Which factor is responsible for the hypertrophy of the
|\ |\ |\ |\ |\ |\ |\ |\ |\
myocardium associated with hypertension? |\ |\ |\ |\
a. Increased norepinephrine
|\ |\ |\
b. Adducin
|\ |\
c. Angiotensin II
|\ |\
d. Insulin resistance
|\ |\
c. Angiotensin II
|\ |\
,What pathologic change occurs to the kidney’s glomeruli
|\ |\ |\ |\ |\ |\ |\ |\
as a result of hypertension?
|\ |\ |\ |\ |\
a. Compression of the renal tubules
|\ |\ |\ |\ |\
b. Ischemia of the tubule
|\ |\ |\ |\
c. Increased pressure from within the tubule
|\ |\ |\ |\ |\ |\
d. Obstruction of the renal tubule
|\ |\ |\ |\ |\
b. Ischemia of the tubule
|\ |\ |\ |\
What effect does atherosclerosis have on the
|\ |\ |\ |\ |\ |\ |\
development of an aneurysm? |\ |\ |\ |\
a. Atherosclerosis causes ischemia of the intima.
|\ |\ |\ |\ |\ |\
b. It increases nitric oxide.
|\ |\ |\ |\
c. Atherosclerosis erodes the vessel wall.
|\ |\ |\ |\ |\
d. It obstructs the vessel.
|\ |\ |\ |\
c. Atherosclerosis erodes the vessel wall.
|\ |\ |\ |\ |\
Regarding the endothelium, what is the difference
|\ |\ |\ |\ |\ |\ |\
between healthy vessel walls and those that promote clot
|\ |\ |\ |\ |\ |\ |\ |\
formation?
|\ |\
a. Inflammation and roughening of the endothelium of the artery
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are present. |\
b. Hypertrophy and vasoconstriction of the endothelium of the
|\ |\ |\ |\ |\ |\ |\ |\ |\
artery are present. |\ |\
c. Excessive clot formation and lipid accumulation in the
|\ |\ |\ |\ |\ |\ |\ |\ |\
endothelium of the artery are present. |\ |\ |\ |\ |\
d. Evidence of age-related changes that weaken the endothelium
|\ |\ |\ |\ |\ |\ |\ |\
of the artery are present.
|\ |\ |\ |\ |\
a. Inflammation and roughening of the endothelium of the artery
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are present. |\
,What is the usual source of pulmonary emboli?
|\ |\ |\ |\ |\ |\ |\ |\
a. Deep venous thrombosis
|\ |\ |\ |\
b. Endocarditis
|\ |\
c. Valvular disease
|\ |\
d. Left heart failure
|\ |\ |\
a. Deep venous thrombosis
|\ |\ |\
What change in a vein supports the development of
|\ |\ |\ |\ |\ |\ |\ |\ |\
varicose veins? |\ |\
a. Increase in osmotic pressure
|\ |\ |\ |\ |\
b. Damage to the valves in veins
|\ |\ |\ |\ |\ |\ |\
c. Damage to the venous endothelium
|\ |\ |\ |\ |\
d. Increase in hydrostatic pressure
|\ |\ |\ |\
b. Damage to the valves in veins
|\ |\ |\ |\ |\ |\
What term is used to identify when a cell is temporarily
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
deprived of blood supply? |\ |\ |\ |\
a. Infarction
|\ |\
b. Ischemia
|\ |\
c. Necrosis
|\
d. Inflammation
|\
b. Ischemia
|\
The risk of developing coronary artery disease is
|\ |\ |\ |\ |\ |\ |\ |\
increased up to threefold by which factor?
|\ |\ |\ |\ |\ |\ |\
a. Diabetes mellitus
|\ |\ |\
b. Hypertension
|\ |\
c. Obesity
|\
, d. High alcohol consumption
|\ |\ |\
b. Hypertension
|\
Which substance is manufactured by the liver and
|\ |\ |\ |\ |\ |\ |\ |\
primarily contains cholesterol and protein?
|\ |\ |\ |\ |\
a. Very low–density lipoproteins (VLDLs)
|\ |\ |\ |\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
c. High-density lipoproteins (HDLs)
|\ |\ |\
d. Triglycerides
|\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
Which elevated value may be protective of the
|\ |\ |\ |\ |\ |\ |\ |\
development of atherosclerosis? |\ |\ |\
a. Very low–density lipoproteins (VLDLs)
|\ |\ |\ |\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
c. High-density lipoproteins (HDLs)
|\ |\ |\
d. Triglycerides
|\
c. High-density lipoproteins (HDLs)
|\ |\ |\
Which laboratory test is an indirect measure of
|\ |\ |\ |\ |\ |\ |\ |\
atherosclerotic plaque? |\ |\
a. Homocysteine
|\
b. Low-density lipoprotein (LDL)
|\ |\ |\
c. Erythrocyte sedimentation rate (ESR)
|\ |\ |\ |\
d. C-reactive protein (CRP)
|\ |\ |\
d. C-reactive protein (CRP)
|\ |\ |\
An individual who is demonstrating elevated levels of
|\ |\ |\ |\ |\ |\ |\ |\
troponin, creatine kinase–isoenzyme MB (CK-MB), and
|\ |\ |\ |\ |\ |\
|\ |\ |\ |\ |\ |\
Review questions with answers |\ |\ |\
What is the initiating event that leads to the development
|\ |\ |\ |\ |\ |\ |\ |\ |\
of atherosclerosis?
|\ |\ |\
a. Release of the inflammatory cytokines
|\ |\ |\ |\ |\
b. Macrophages adhere to vessel walls.
|\ |\ |\ |\ |\
c. Injury to the endothelial cells that line the artery walls
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
d. Release of the platelet-deprived growth factor
|\ |\ |\ |\ |\ |\
c. Injury to the endothelial cells that line the artery walls
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
What is the effect of oxidized low-density lipoproteins
|\ |\ |\ |\ |\ |\ |\ |\
(LDLs) in atherosclerosis?
|\ |\ |\
a. LDLs cause smooth muscle proliferation.
|\ |\ |\ |\ |\
b. LDLs cause regression of atherosclerotic plaques.
|\ |\ |\ |\ |\ |\
c. LDLs increase levels of inflammatory cytokines.
|\ |\ |\ |\ |\ |\
d. LDLs direct macrophages to the site in the endothelium.
|\ |\ |\ |\ |\ |\ |\ |\ |\
a. LDLs cause smooth muscle proliferation.
|\ |\ |\ |\ |\
Which factor is responsible for the hypertrophy of the
|\ |\ |\ |\ |\ |\ |\ |\ |\
myocardium associated with hypertension? |\ |\ |\ |\
a. Increased norepinephrine
|\ |\ |\
b. Adducin
|\ |\
c. Angiotensin II
|\ |\
d. Insulin resistance
|\ |\
c. Angiotensin II
|\ |\
,What pathologic change occurs to the kidney’s glomeruli
|\ |\ |\ |\ |\ |\ |\ |\
as a result of hypertension?
|\ |\ |\ |\ |\
a. Compression of the renal tubules
|\ |\ |\ |\ |\
b. Ischemia of the tubule
|\ |\ |\ |\
c. Increased pressure from within the tubule
|\ |\ |\ |\ |\ |\
d. Obstruction of the renal tubule
|\ |\ |\ |\ |\
b. Ischemia of the tubule
|\ |\ |\ |\
What effect does atherosclerosis have on the
|\ |\ |\ |\ |\ |\ |\
development of an aneurysm? |\ |\ |\ |\
a. Atherosclerosis causes ischemia of the intima.
|\ |\ |\ |\ |\ |\
b. It increases nitric oxide.
|\ |\ |\ |\
c. Atherosclerosis erodes the vessel wall.
|\ |\ |\ |\ |\
d. It obstructs the vessel.
|\ |\ |\ |\
c. Atherosclerosis erodes the vessel wall.
|\ |\ |\ |\ |\
Regarding the endothelium, what is the difference
|\ |\ |\ |\ |\ |\ |\
between healthy vessel walls and those that promote clot
|\ |\ |\ |\ |\ |\ |\ |\
formation?
|\ |\
a. Inflammation and roughening of the endothelium of the artery
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are present. |\
b. Hypertrophy and vasoconstriction of the endothelium of the
|\ |\ |\ |\ |\ |\ |\ |\ |\
artery are present. |\ |\
c. Excessive clot formation and lipid accumulation in the
|\ |\ |\ |\ |\ |\ |\ |\ |\
endothelium of the artery are present. |\ |\ |\ |\ |\
d. Evidence of age-related changes that weaken the endothelium
|\ |\ |\ |\ |\ |\ |\ |\
of the artery are present.
|\ |\ |\ |\ |\
a. Inflammation and roughening of the endothelium of the artery
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are present. |\
,What is the usual source of pulmonary emboli?
|\ |\ |\ |\ |\ |\ |\ |\
a. Deep venous thrombosis
|\ |\ |\ |\
b. Endocarditis
|\ |\
c. Valvular disease
|\ |\
d. Left heart failure
|\ |\ |\
a. Deep venous thrombosis
|\ |\ |\
What change in a vein supports the development of
|\ |\ |\ |\ |\ |\ |\ |\ |\
varicose veins? |\ |\
a. Increase in osmotic pressure
|\ |\ |\ |\ |\
b. Damage to the valves in veins
|\ |\ |\ |\ |\ |\ |\
c. Damage to the venous endothelium
|\ |\ |\ |\ |\
d. Increase in hydrostatic pressure
|\ |\ |\ |\
b. Damage to the valves in veins
|\ |\ |\ |\ |\ |\
What term is used to identify when a cell is temporarily
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
deprived of blood supply? |\ |\ |\ |\
a. Infarction
|\ |\
b. Ischemia
|\ |\
c. Necrosis
|\
d. Inflammation
|\
b. Ischemia
|\
The risk of developing coronary artery disease is
|\ |\ |\ |\ |\ |\ |\ |\
increased up to threefold by which factor?
|\ |\ |\ |\ |\ |\ |\
a. Diabetes mellitus
|\ |\ |\
b. Hypertension
|\ |\
c. Obesity
|\
, d. High alcohol consumption
|\ |\ |\
b. Hypertension
|\
Which substance is manufactured by the liver and
|\ |\ |\ |\ |\ |\ |\ |\
primarily contains cholesterol and protein?
|\ |\ |\ |\ |\
a. Very low–density lipoproteins (VLDLs)
|\ |\ |\ |\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
c. High-density lipoproteins (HDLs)
|\ |\ |\
d. Triglycerides
|\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
Which elevated value may be protective of the
|\ |\ |\ |\ |\ |\ |\ |\
development of atherosclerosis? |\ |\ |\
a. Very low–density lipoproteins (VLDLs)
|\ |\ |\ |\
b. Low-density lipoproteins (LDLs)
|\ |\ |\
c. High-density lipoproteins (HDLs)
|\ |\ |\
d. Triglycerides
|\
c. High-density lipoproteins (HDLs)
|\ |\ |\
Which laboratory test is an indirect measure of
|\ |\ |\ |\ |\ |\ |\ |\
atherosclerotic plaque? |\ |\
a. Homocysteine
|\
b. Low-density lipoprotein (LDL)
|\ |\ |\
c. Erythrocyte sedimentation rate (ESR)
|\ |\ |\ |\
d. C-reactive protein (CRP)
|\ |\ |\
d. C-reactive protein (CRP)
|\ |\ |\
An individual who is demonstrating elevated levels of
|\ |\ |\ |\ |\ |\ |\ |\
troponin, creatine kinase–isoenzyme MB (CK-MB), and
|\ |\ |\ |\ |\ |\