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BIO 400: EXAM 4 DNA REPAIR 1 QUESTIONS WITH COMPLETE SOLUTIONS

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BIO 400: EXAM 4 DNA REPAIR 1 QUESTIONS WITH COMPLETE SOLUTIONS

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BIO 400: EXAM 4 DNA REPAIR 1



DNA damage - Correct Answers -abnormal chemical structure in DNA

DNA mutation - Correct Answers -change in the sequence of base pairs

Point mutation - Correct Answers -changes in 1 or a few nucleotides

Substitution: transition - Correct Answers -purine for purine, pyrimidine for pyrimidine

Substitution: transversion - Correct Answers -purine for pyrimidine, pyrimidine for purine

Indel - Correct Answers -insertion or deletion of nucleotides

Chromosome abnormality - Correct Answers -changes in number and structure of entire
chromosomes

Inherited - Correct Answers -parent to child

Acquired - Correct Answers -environmental damage, DNA replication errors

Neutral mutations - Correct Answers -eye color, birth marks
Silent mutation (synonymous mutation) - Correct Answers -base pair substitution results
in the same amino acid

Nonsense mutation - Correct Answers -nucleotide mutation results in a stop codon and
shorter polypeptide

Frameshift mutations - Correct Answers -deletions or insertions (not divisible by 3) can
change the reading frame (the grouping of codons) resulting in a completely different
translation from the original

Harmful mutations that cause genetic disorders - Correct Answers -sickle cell anemia,
down syndrome

Beneficial mutations - Correct Answers -sickle cell anemia to malaria, immunity to HIV

cancer incidence increases dramatically with - Correct Answers -age

a single nucleotide change causes what disease - Correct Answers -sickle-cell anemia

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