PHARMACEUTICAL CALCULATIONS perfect exam samples calculation questions with answers 2021 docs

PHARMACEUTICAL CALCULATIONS perfect exam samples calculation questions with answers 2021 docs 8. How many grams of digoxin would be required to make 15,000 tablets each containing 250 mcg of digoxin? A. 500 g B. 3.75g C. 2.5 g D. 5 g E. 15g 9. An injection contains 40mg/0.8 ml of drug. How many ml should be administered to provide 75mg of the drug? A. 1.5 ml B. 2 ml C. 7.5 ml D. 0.4ml E. 0.8 ml 10. An oral inhalation for asthma contains 100 mcg of mometasonefumarate per inhalation. If the patient is directed to use the inhaler as "two inhalations twice daily" What would be the amount of each drug inhaled daily? The answers should be expressed in mg A. 0.2 mg mometasone. 0.01mg formoterol B. 0.4 mg mometasone, 0.02 mg formoterol C. 0.6mg mometasone, 0.03 mg formoterol D. 0.8 mg ,mometaspme 0.04 mg formoterol E. 1mg mometasone, 0.05mg formoterol 11. A prefilled syringe contains 2 mg of active drug in 5ml of solution. How many micrograms of drug is administered by injecting 0.5ml of the solution? A. 0.2 mcg B. 400 mcg C. 0.4 mcg D. 200 mcg E. 215 mcg 12. A salbutamol inhaler contains 75 mcg of drug per inhalation. How many inhalation doses could be delivered if the inhaler contains 20 mg of salbutamol? A. 267 inhalataions B. 250 inhalations C. 325 inhalations D. 472 inhalations E. 752 inhalations 13. What does the abbreviation of prn means? A. AS needed B. By mouth C. Repeat D. At bedtime E. As directed 14. An otic solution containing 0.2 mg of active ingredient in 2.5ml containers. What is the percent strength of the active ingredient in the solution? A. 0.08% w/v B. 0.008% w/v C. 0.04 % w/v D. 0.95 % w/v 15. RX. Potassium permanganate 0.03% Purified water ad 250ml Sig as directed Determine the amount of potassium permanganate that should be used to compound the prescription. A. 30g B. 0.075g C. 0.3g D.7.5g E 250 g 16. Rx Ofloxacin 0.3% Disp 5 ml Determine the amount in mg of ofloxacin contained in each ml of Rx A. 3mg B.3.7 mg C.10.2 mg D. 12.5 mg E. 1.72 mg 17. The following are recommended doses for certain nicotine patch one 21 mg dose per day for 6 weeks one 14 mg dose per day for 2 weeks one 7 mg dose per day for 2 weeks A. 11.75 g B. 1.176 g C. 0.168 g D. 1.68g E. 117.6 g 18. The following are the components of a triphasic birth control pill: Phase 1 6 tablets Phase 2 5 tablets 0.0175 mg levonorgestrel 0.03 mg ethinyl estradiol phase 3 10 tablets 0.125 mg levonorgestrel 0.03 mg ethinyl estradiol 7 tablets inert If the direction is to take on tablet by mout every day, what is the total amount of levonorgestrel and ethinyl estradiol taken by the patient during the 28 day theraphy? A. 200 mg levonorgestrel; 1mg ethinylestradiol B. 1.925 mg levonorgestrel; 0.68 mg ethinyl estradiol C.2.35 mg levonorgestrel; 0.75 mg ethinyl estradiol D. 215 mg levonorgestrel; 1.78 mg ethinyl estradiol E. 1.777 mg levonorgestrel; 1.453 mg ethinyl estradiol 19.Determine the specific gravity of the liquid given the following information: Weight of specific gravity bottle = 25.05g Weight of bottle when filled with water= 73.72 g WEight of bottle when filled with another liquid =74.56 g A. 1.13 B.5.521 C. 1.027 D. 1.008 E. 0.576 20. If the specific gravity of 2542 ml is 0.63 determine tthe weight in grams of the alcohol A. 1601g B. 123 g C. 63g D. 473g E. 794 g 21. Determine the weight in grams of 3 of a liquid with a specific gravity of 0.94 A. 83.39g B. 95g C.9.4g D. 30g E. 15g 22. Determine the volume in ml of a liquid weighing 1 lb and with a of 1.176 A. 300 ml B. 466 ml C. 386 ml D. 472 ml E. 176 ml 23. Determine the cost of 500 ml of glycerin with a of 1.25 that is bought at 510 pesos per kilogram A. 300.25 B. 275 C. 297.45 D. 318.75 E. 523 24. Determine the cost of 3 pints of a liquid with a of 1.567 and is bought at 2,350 per kilogram A. 5225.40 pesos B. 6643 pesos C. 297 .45 pesos D. 318.75 pesos E. 523 pesos 25. Determine the density of 125 ml of liquid weighing 278g A. 2.224 B.3.475 C. 22.56 D. 2.232 E. 3.225 26. What is the weight in kilogram of 2L of a liquid with a of 0.97 A. 1.75 kg B. 1.94 kg C. 1.27kg D. 1.57 kg E. 1.87 kg 27.Determine the volume in ml, of 3 lb of benzyl benzoate having a of 1.12 A. 1216 ml B. 1500ml C. 1362 ml D. 1000ml E. 2560ml 28.Given the ff formulation determine the total weight of the formula for a chewable gummy gel medication base. Gelatin 400g Glycerin 150ml ( 1.25) Purified water 25 ml A. 75g B. 612.5 g C. 325.5g D. 273.5g E. 204.5 g 29. If the dose of a drug is 50 mcg, how many doses are in 0.04 g? A. 250 doses B. 750 doses C. 800 doses D. 415 doses E. 525 doses 30. Rx Sol.Silver Nitrate 0.5% 15 (E=0.33) Make isotonic Solution Sig for eyes How many grams of pottasium nitrate (E0.58) should be used to make the prescription isotonic? a.0.11g b.0.05g c.0.19g d.1.72g e.0.1125g 31. A syrup contains 7.5 % of potassium chloride (MWt.=74.5) How many millimoles of K+ are contained in 1 ml of this syrup? a.1.92millimoles b.1millimole c.0.19millimole d.7.5millimole e.1.8millimole 32. Teratogenic studies of insulin glargine were undertaken in rats at doses up to 0.36 mg/kg/day. This is equivalent of the following? a.792 mcg/lb/day b.360 mcg/lb/day c.360 mcg/lb/day d.163.6 mcg/lb/day e.792 mcg/lb/day 33. LEVAQUIN (levofloxacin) injection contains 5mg/mL of levofloxacin and 5% dextrose. How much of each would be delivered to a patient upon the administration of a 100mL injection? a. 5g levofloxacin and 5g dextrose b. 50mg levofloxacin and 5g dextrose c. 500mg levofloxacin and 500mg dextrose d. 0.5g levofloxacin and 5g dextrose e. 500mg levofloxacin and 50g dextrose 34. A 142-lb patient was receiving filgrastim (NEUPOGEN) in doses of 10mcg/kg/day, as a result of successful blood test, dose was lowered to 6mcg/kg/day. Using an injection containing 0.3mg filgrastim per o.5mL, calculate the previous and new dose to be administered: a. 7.7mL and 64.6mL b 5.23mL and 3.14mL c. 1.08mL and 0.65mL d. 3.87mL and 2.3mL e. 3.14mL and 0.65mL 35. How many grams of pure drug are in 50mL of a 25% glucose solution? a. 3g b. 8.75g c. 12.5g d. 18g e. 1.25g 36. Ancell, a 15 year-old boy, weigh 98 pounds and is to receive an initial insulin dose for hyperglycemia and ketonuria. The prescription reads, “regular insulin 0.1 U/kg SQ QID.” How many units of regular insulin will ancell receive at each dose? a. 98 U/dose b. 4.5 U/dose c. 45 U/dose d. 98 U/dose e. 4.4 U/dose 37. If 250 mL of alcohol weighs 1285 grams, what its specific gravity? a. 1.232 g/mL b. 0.812 g/mL c. 80 g/mL d. 1.223 g/mL e. 0.821 g/mL 38. 122. If a liter of a cough syrup weighs 1285 grams, what its specific gravity? a. 1.258 b. 1.285 c. 0.778 d. 0.78 e. 0.87 39. A physician prescribed Keflex 250 mg QID x 10 d, how many ml of Keflex suspension containing 250 mg per 5 ml should be dispensed? a. 200ml b. 2ml c. 62.5ml d. 6.25ml e. 20ml 40. A glucose meter shows that a patient’s blood contains 125 mg% of glucose. Express this value as mg/ml. a. 1.25 mg/mL b. 12.5 mg/mL c. 12 mg/mL d. 0.125 mg/mL e. 0.0125 mg/mL 41. An adult accidentally swallowed 36 NaF (MWt.=42) tablets containing 2 mg of NaF per tablets. How many mEq of sodium were ingested? a. 1.71 mEq b. 0.78 mEq c. 3024 mEq d. 7.8 mEq e. 1.17 mEq 42. How many mL each of purified water and an isotonic sodium chloride solution should be use to prepare 30mL of a 1% w/v isotonic solution of Fentanyl Citrate (E=0.11)? a. 3.67 mL Purified water & 26.33 mL NaClsol’n b. 36.7 mL Purified water & 26.33 mL NaClsol’n c. 26.33 mL Purified water & 3.67 mL NaClsol’n d. 367 mL Purified water & 26.33 mL NaClsol’n e. None of the above 43. Rx Cisapride 1mg/mL Orasweetad 120mL How many 10 mg-tablets Cisapride may be used in compounding the prescription? a. 10-10mg tabs b. 12-10mg tabs c. 2-10mg tabs d. 5-10mg tabs e. 6-10mg tabs 44. Lanoxin pediatrics elixir contains 0.05 mg of digoxin per mL. How many micrograms are there in 3 mL of elixir? a. 0.0015 b. 0.015 c. 0.15 d. 1.5 e. 150 45. Calcium chloride (CaCl2.2H2O) has a formula weight of 147. What weight of the chemical is needed to obtain 40 mEq of calcium? (Ca=40; Cl=35.5; H2O=18) a. 0.80g b. 2.22g c. 1.47g d. 2.94g e. 5.88g 47. Calcium gluconate comes in vial of 1 g per 10 mL. The prescription indicates that you should give the patient 320 mg of calcium gluconate. Calculate the number of mL per dose that your patient should have. a. 3200 mL/dose b. 3.2 mL/dose c. 0.032 mL/dose d. 320 mL/dose e. 32 mL/dose 48. A physician prescribes 60mL of penicillin containing 4,800,000 units. How many penicillin unit will be represented in each teaspoonful dose of the prepared suspension? a. 400,000 unit b. 80,000 units c. 40,000 units d. 320,000 units e. 960,000 units 49. A hospital Pharmacist combined 2 fluidonces of a povidone-iodine cleaner, 7.5%w/v, with 4-fluidounces of a povidone-iodine topical solution, 10% w/v, Calcuate the resulting strength of a povidone-iodine mixture. a. 0.11% b. 9% c. 9.17% d. 11% e. 9.71% 50. Saint john'swort is administered as 100 mg capsules to be taken TID, if this herb is standardized to contain 0.5% hypericin extract, how many mg of the extract would be taken daily? A. 0.5 mg B. 1.5 mg C. 100 mg D. 50 mg E. 150 mg 51. A hospital medication order calls for the isophane insulin suspension to be administered to a 145 lb patient on the basis of 1 unit/kg per 24 hours. How many units of isophane insulin suspension should be administered safely for this patient? a. 65.9 units per 24 hours d. 68.5 units per 24 hours b. 67.2 units per 24 hours e. 69.1 units per 24 hours c. 66.3 units per 24 hours 52. Creon, a pancrealipase product, contains 3000 units of lipase. 9500 units of protease, and 15,000 units of amylase in a delayed release capsule. The instruction is for the capsules to be swallowed whole of the contents added uncrushed to food immediately prior to administration. The dose should not exceed 2,000 lipase units/kg body weight. If the content of one capsule is added to 180 ml feeding formula for a 15 lb infant, is the dose within acceptable limits? a. Yes, it is within acceptable limits d. All of the above b. No, it is not within acceptable limits e. None of the above c. It cannot be determined given the data 53. A cancer patient is taking one 30 mg oxycodone tablet q. 6 h. prn, pain. The patient’s pain management doctor decides to switch the patient to fentanyl transdermal patches. Referring to the date below, what strength of the patches should be prescribed to this patient? Daily dose: Oral oxycodone 30-67 67.5-112 112.5-157 157.5-202 Fentanyl 25 mcg/hr 50mcg/hr 75mcg/hr 100mcg/hr a. No need to change to the patches d. 10ml/hr b. 25mcg/hr e. 45ml/hr c. 5omcg/hr 54. Using the Cockcroft-Gault equation, determine the clearance rate for an 80 year old male patient weighing 72kg and having a serum creatinine of 1.5mg/dl. a. 25 ml/min d. 0.4 ml/min b. 40 ml/min e. 0.5 ml/min c. 35 ml/min 55. A medication order indicates 1500 units of heparin to be administered vi IV infusion per hour. The pharmacy provides a heparin IV bag containing 20,000 units of heparin in 250 ml D5W. Determine how many ml should be administered per minute. a. 0.1 ml/min c.10 ml/min b. 0.2 ml/min d. 45 ml/min c. 0.3 ml/min 56. Interpret the ff. signa. Sig. gtt iii each eye q 4 h p.r.n. pain a. Instill 3 ml into each eye for pain d. Take 3 drops for each eye four times daily b. Instill 3 drops each eye every 4 hours as needed for pain c. Take 3 ml for each eye every 4 hours for pain e. Insert 3 drops each eye four times daily as needed for pain 57. Interpret the ff from the medication order: Admin. Prochlorperazine 10mg IM q 4 h p.r.n N&V a. Instill 10mg Prochlorperazine every four hours as needed b. Take Prochlorperazine 10 mg by mouth every four hours as needed for nausea and vomiting c. Administer 10 mg Prochlorperazine intramuscularly every four hours as needed for nausea and vomiting d. intramuscularly Prochlorperazine 10 mg every four hours as needed. e. None of these 58. Interpret the ff: Potassium chloride 10 mEqpob.i.d pc a. Take 10 milliequivalents of potassium chloride by mouth twice daily after meals b. Take 10 milliequivalents of potassium chloride by mouth twice daily before meals c. Take 10 milliequivalents of potassium chloride by mouth twice daily after meals as needed d. Take 10 milliequivalents of potassium chloride by mouth twice at bedtime e. None of these 59. A prescription for drug A was brought to the pharmacy, indicating the ff: 1 tablet q.i.d the first day 1 tablet t.i.d the second day 1 tablet b.i.d x 7 days 1 tablet q.i.d thereafter How many tablets should be dispensed for 60 days supply of medication? a. 75 tablets d. 21 tablets b. 72 tablets e. 42 tablets c. 77 tablets 60. Interpret the ff: ii tab po 6 h. ATC pain a. Take two tablets every 6 hours around the clock as needed for pain b. Instill two tablets by mouth for times a day as needed c. Take two tablets by mouth every 6 hours around the clock for pain d. Take two tablets as needed for pain around the clock e. None of there 61. A capsule contains the following amounts of medical agents: 0.025g, 15g,0.0003g, 2mg and 125mg. Determine the total weight of the me1ical agents in the capsule. a. 167.3g d. 15.025mg b. 15.025g e. 167.3mg c. 325mg 62. An IV solution contains 300mcg of the drug per ml. How many milligrams of the drug would a patient receive from an IV infusion of 1500ml of the solution? a. 250mcg d. 450mcg b. 500mcg e. 150mcg c. 300mcg 63. One half liter of the solution for IV infusion contains 3g of drug. How many ml of the infusion would contain 0.7mg of drug? a. 1.17mg d. 0.7mg b. 0.117mg e. 0.2mg c. 30mg 64. A salbutamol inhaler contains 20 mg of drug. How many inhalation doses can be delivered if each inhalation dose contains 100mcg? a. 100 inhalations d. 300 inhalations b. 200 inhalations e. 400 inhalations c. 250 inhalations 65. A patient was administered 200 ml of D5W at a rate of 20 ml/hr. If the infusion was begun at 10 am, at what time was the infusion completed? a. 10 PM d. 2 PM b. 6 PM e. 12 PM c. 8 PM 66. A pediatric is administered 75 ml of an infusion at 10 drops/min. determine the duration of the infusion in minutes if an administration set the delivers 30 drops/ml is used? a. 450 mins d. 300 mins b. 400 mins e. 250 mins c. 350 mins 67. An emergency syringe contains 1g/5ml of lidocaine. How many ml should be used to prepare 125 ml of an infusion to contain 2mg/ml of lidocaine in D5W? a. 2.25 ml d. 1.5 ml b. 2.0 ml e. 1.0 ml c. 1.25 ml 68. An intravenous drip contains 3 g of lidocaine hydro chloride and is administered t a rate of 5 mg/min a.600 minutes d.300 minutes b.500 minutes e.200 minutes c.400 minutes 69. A 160 lb patient has been administered intaveneousimmunoglublin (IVIG) at a rate of 0.05 ml/kg/min. How many mL is administered over a period of 6 hours a.1420 mL d.1150 mL b.1309 mL e.1030 mL c.1255 mL 70. A pharmacist receives a medication order for 400,000 units of pencillin G potassium to be added to 500 mL of D5w. the direction on the vial reads that if 1.5 mL of solvent is added, the solution containing 1,000,000 units will now measure 2 mL.determine the amount of solution that should be added D3W? a. 0.5 mL d. 1.25 mL b. 0.8mL e. 2 mL c. 1 mL 71.A medication order indicates 1.5 g of an antibiotic to be added to 100mL of D5W. how many mL of a 250 mg/3mL injection should be added to D3W to prepare this medication order? a.12 mL d.20 mL b.15 mL e.22 ml c.18 mL 72. In addition to the active ingredient in an oral solution, it also contains 40.5% of alcohol and 23.8% propylene glycol. Determine the quantities of the 2 ingredients in a 240 mL bottle of oral solution. a.77.3 mL alcohol; 57.12 mL propylene glycol d. 97.2mL alcohol; 57.12 mL propylene glycol b77.3 mL alcohol; 67.4 mL propylene glycol e. 87.3 mL alcohol; 45.6 mL propylene glycol c. 79.4 mL alcohol; 47.62 mL propylene glycol 73 If 240 ml of ranitidine syrup contains 2.3 g of ranitidine, how many mg of ranitidine would been administered in a patient who takes 1 teaspoonful of the syrup? a.47.9 mg d.51.8mg b.50.3 mg e.45.2 mg c.42.7 mg 74. If pediatric patient requires a 0.02 mg dose of digoxin, what volume of an 80 mcg per mL injection should be administered a.0.5 mL d.0.8 mL b.0.25 mL e.1 mL c.0.45 mL 75. A patient with glaucoma brings in a prescription for Alphagan P with a signa of 1 drop in the affected eyes three times daily. Alphagan P contains 0.15% Brimonidine tartrate per 10 mL bottle. How many mg brimonidine tartrate is administered daily if the patient is to treat both eyes and dropper used delivers 20 drops per mL? a. 0.25mg d. 0.55mg b. 0.3mg e. 0.6mg c. 0.45mg 76. A fluticasone nasal spray preparation contains 45 mcg of fluticasone propionate per actuaion spray in each 100 mg formulation. How many mg of fluticasone propionate is contained in each container if each container provides 100 sprays? a. 5mg d. 4.5mg b. 3mg e. 4mg c. 10mg 77. If the normal daily dose of gentamicin is 3mg/kg/day and administered in 3 divided doses, what would be the single (8 hour) dose for a 123lb patient and scheduled to receive 45% of the usual dose base on renal impairment? a. 32.08mg d. 28.25mg b. 20.15mg e. 75.5mg c. 25.16mg 78. Determine how many teaspoonfuls of an oral solution should be administered to a 145 lb patient if the recommended adult dose is 0.3ml/kg of body weight. a. 4 tsp d. 2 tsp b. 8 tsp e. 3 tsp c. 6 tsp 79. A 45 lb child has been prescribed with the dimenhydrinate, where the labeled dose of the drug reads 1.3 mg/kg. The available oral solution contains 12.5 mg/5 mL of dimenhydrinate. The nurse checked with the hospital pharmacist in her calculated dose of 10.6 mL is correct. What would you tell her? a. Her calculations is correct d. None of these b. Her calculations is incorrect e. All of these c. Her calculations is no basis 80. A 145 lb patient was receiving filgrastim in doses of 10mcg/kg/day. When blood test results arrived, her dosewas lowered 7mcg/kg/day. If an injection containing 0.3 m filgrastim per 0.5 mL is used, determined the previous and new dose to be administered to this patient. a. 2 mL previous dose; 1 mL new dose d. 3.4 mL previous dose; 1 mL new dose b. 1.1 mL previous dose; 0.92 mL new dose e. 1 mL previous dose; 0.68 mL new dose c.1.75 mL previous dose; 0.87 mL new dose 81. if the pediatric dose for an antibiotic is 7 mg/kg q 12 h, what is the daily dose in mg for a child weighing 47 lb? a. 299 mg/day d. 257 mg/day b.459 mg/day e. 302 mg/day c.377 mg/day 82.If the daily dose of an antibiotic for a pediatric patient is 314 mg/day, How many teaspoon should be administered if a suspension containing 125mg/day is given to the patient? a.2tsp d.3 1/2 tsp b. 2 ½ tsp e.4 tsp c. 3 tsp 83. What is the daily dose in mg for a child with a BSA of 0.45 m2 if the recommended dose is 8mg/m2/day? a. 4.5mg/day d. 2.8 mg/day b. 5.9mg/day e.1.2 mg/day c. 3.6 mg/day 84.A patient receive and injection of an anticoagulant drug at a dose of 20 mg prior to hit replacement surgery. After the surgery the drug injected at a dose of 1 mg/kg. what is the total pre- and post-surgery doses for this patient who weighs 138 lb a.25 mg d.55 mg b.83 mg e.76 mg c.60 mg 85. If the recommended pediatric dose for cefexime is 7.5 mg/kg/day, how many ml should be dispensed for a 10 day course of therapy for a 50 lbpatient?the available preparation in the pharmacy is 100 mg/5 mL. a.90 mL d.120 mL b.50 ml e.75 mL c.45 mL 86. Androgel 1.6% is a testosterone gel for topical used. Determined the number of grams required to provide a 48.6 mg dose of testosterone. a.1.5 g d.1.6 g b.2 g e.3 g c.4.8 g 87. Determine the amount in mg of methylparaben needed to prepare 8 fluid ounces of solution containing 0.12% w/v of methyl paraben a. 283.87 mg d.215.57 mg b.255.23 mg e.229.72 mg c. 274.33 mg 88. The contents of 8 75mg oseltamivir (Tamiflu) capsules were emptied into a liquid vehicle to prepare 60 mL of suspension. What is the percent strength of oseltamivir in the preparation. a.1% d.7.5 % b.1.5% e.2 % c.6% 89. beractant suspension is available in 4 mL via containing 25 mg of drug per mL, and the dose is 100 mg/kg is birthweight. This is administered via intratracheal route to premature infants within 15 minutes of birth, as indicated for the prevention and treatment of a respiratory distress syndrome. What is the dose of a newborn weighing 4.5 lb? a.4.5 mL d.5.25 ml b.8.18 mL e.9 mL c.4 mL 90. What would be the quantities for a 176 lb patient of the neurologic drug divaltroex solution if the recommended initial dose is 25 mg/kg/day to be increased as in indicated to a maximum dose of 60 mg/kg/day a. 2500 mg/day initial, 6000 mg/day max b. 3050 mg/day initial, 4800 mg/day max c. 1500 mg/day initial, 3000 mg/day max d. 2000 mg/day initial, 4800 mg/day max e. 2000 mg/day initial, 2500 mg/day max 91. As pharmacist what strength tablet and quantity would you recommend for an initial dose of 2000mg divaltroex sodium, if the drug comes in 250 mg and 500 mg strength tablets ? a. five 250 mg tablets as initial dose b. four 500mg tablets as initial dose c. two 1000mg tablet as initial dose d. two 500 mg tablets as initial dose e. seven 250 mg tablets as initial dose 92.a prescription indicates 3 million units per pencillin G potassium daily for 1 week. If 1 unit of penicillin G potassium equals 0.9 mcg/mg, How many 250 mg tablet should be dispense to complete therapy a. 11 tablets b. 7 tablets c. 21 tablets d. 35 tablets e. 77 tablets 93. Adult doses calcitoninin of up to 32 units per kg do not produce any adverse a 140lb patient were administered 0.8 mL injection, would adverse effect be observed? Note calcitonin is available as 200 international units/ml injection. a. No b. Yes c. There is not enough data to tell d. Maybe e. Not applicable 94. What would be the days supply for 10 ml vial insulin glargine (lantus), 100 units per ml, if a patient’s starting dose is 15 units, and a daily maintenance dose of 8 units? a. 30 days b. 15 days c. 124 days d. 45 days e. 60 days 95. Determine the creatinine clearance for this patient using the jeliffe equation Gender; Male Age; 54 years old Weight; 75 kg serum creatinine 1.2 mg/dl a.12 ml/min d. 54 ml/min b.75ml/min e.98 ml/min c.59 ml/min 96. Using the cockroft-gault equation determine creatinine clearance rate for 18 years old male weighing 75 kg with a serum creatinine 1.7 mg/dl. a. 36.76 ml/min b. 75.12 ml/min c. 16.27 ml/min d. 54 ml/min e. 14.72 ml/min 97. Using the cockroft-gault equation determine the creatinine clearance rate for the patient gender;female weight;70kg age;75yrs old serum creatinine;1mg/dl Gender; Female Age; 75 years old Weight; 70 kg Serum creatinine 1mg/dl a. 63.9 ml/mim b. 53.72 ml/min c. 72 ml/min d. 56.9 ml/min e. 50.81 ml/min 98. A hospital pharmacy order indicate 400 units of heparin to administered SC twice daily for the prevention of blood clots. The pharmacist has obtained of vial heparin containing 15,000 heparin units/ml. Determine the amount in ml of the injection that should be administered for each dose. a. 0.15 ml b. 0.54 ml c. 0.37 ml d. 0.4 ml e. 0.75 ml 99.Determined the ideal body weight in pounds of a 72 year old female patient who is 5 feet and 8 inches tall and weighs 168 lb. a. 120 lb b. 164 lb c. 125 lb d. 100 lb e. 170 lb 100. Detemined the IBW in kilograms for a 65 years old male patient who is 5 feet and 8 inches tall who weighs 168 lb. a. 74.6 kg b. 68.4 kg c. 95.3 kg d. 65.7 kg e. 45.21 101.If a patient is found out to have a serum cholesterol level of 210mg/dL, what is the equivalent value expressed in mmol/L? (MW of cholesterol=387) A)2.77mmol/L B)5.43mmol/L C)210mmol/L D)6.17mmol/L E)5.21mmol/L 102.Determine the adjusted body weight in kilograms for a 55year old male patient who is a 6 feet tall and weighs 288lb A)101.3kg B)89.7kg C)90.93kg D)77.6kg E)130.9kg 103.The initial dose of atracuriumbesylate is 0.4mg/kg and this should be dosed based on IBW for obese patients.Given the following patient details, determine the amount in mL of a 10mg/mL injection that should be administered to this patient Age:42 years old, male Height:6 feet Weight:250lb A)1.7mL B)3.8mL C)2.1mL D)3.1mL E)2.7mL 104.What is the percent reduction reqired for a patient who is instructed by her doctor to reduce her LDL from 140mg/dL? A)28.57% B)15.87% C)52.1% D)23.17% E)29.87% 105.What is the equivalent of glucose reading of 145mg/dL in mmol/L? (Conversion factor is 0.055) A)7.98mmol/L B)5.81mmol/L C)4.52mmol/L D)6.23mmol/L E)8.97mmol/L 106. Rx Ephedrine sulfate 0.25g (E=0.2) Sodium chloride q.s Purified water 30mL Make isoton sol. Sig. Use as directed How much sodium chloride should be used to compound the solution? A)100mg B)30mg C)110mg D)220mg E)50mg 107. Rx Zinc sulfate 0.07g (E=0.16) Boric acid q.s (E=0.52) Purified water ad 30mL Make isoton sol. Sig. Drop in eyes as directed Determine the amount of boric acid to be used in compounding the prescription A)134.58mg B)258.8mg C)270mg D)300mg E)723.4mg 108.Anotic suspension containing 0.3% w/v ciprofloxacin and 0.1% w/v dexamethasone in a 5mL drop container.Calculate the quantities of each agent in mg/mL A)10mg ciprofloxacin;5mg dexamethasone B)15mg ciprofloxacin;5mg dexamethasone C) 15mg ciprofloxacin;10mg dexamethasone D) 30mg ciprofloxacin;10mg dexamethasone E) 12mg ciprofloxacin;7mg dexamethasone 109.A topical solution contains 3% w/v hydroquionone.How many L of the solution can be prepared from 60grams of hydroquinone? 109.A topical solution contains 3% w/v hydroquionone.How many L of the solution can be prepared from 60grams of hydroquinone? A)2L B)3L C)60L D)5L E)10L 110.How many millimeters of a cascara sagrada fluidextract can be prepared from 2 pounds of a cascara sagrada bark? A)454mL B)908mL C)300mL D)250mL E)785mL 111.Norgestrel and Ethynyl estradiol tablets are available containing 0.5mg on norgestrel and 50mcg of ethynylestradiol.How many grams of each ingredient would be used in makinb 50,000 tablets? A)2.5g norgestrel;2.5g ethynyl estradiol B)30g norgestrel;9.5g ethynyl estradiol C) 25g norgestrel;2.5gethynyl estradiol D) 55g norgestrel;2.5gethynyl estradiol E) 25g norgestrel;3.5gethynyl estradiol 112.Pergolidemesylate is an adjunctive treatment to levodopa/carvidopa in the management of Parkinson's disease has this recommended dosing for a patient A. One 50mcg tablet for days 1,2 150mcg/day on days 3,4,5 250mcg/day on day 9 Then the patient should return to the doctor for assessment.Determine the total amount of the drug in mg, taht is taken by this patient during the course of treatment. A)2.8mg B)1.65mg C)8.1mg D)4.5mg E)7.5mg 113.Roxanol concentrate contains 20mg/mL of morphine sulfate and is available as 30mL bottle with a calibrated dropper.How many mg of morphine sulfate is delivered by a 0.8mL dose? A)14mg B)20mg C)16mg D)1.6mg E)25mg 114.A prescription calls for 900mg of drug A.After weighing this amount on a balance, which registers a weight only a 850mg.What is the percentage of error between the two weighing? A)2.25% B)5.56% C)1.05% D)9.4% E)10% 115.In compounding a precription the pharmacist weighs 0.08g of a substance on a balance sensitive to quantities smaller than 0.004g.What was the maximum potential error in terms of percentage? A)2% B)3% C)4% D)5% E)6% 116.A pharmacist attempts to weigh 240mg of codeine sulfate on a balance with a sensitivity requirement of 6mg.What is the maximum potential error in terms of percentage? A)2.5% B)3.4% C)6.1% D)5.2% E)7.1% 117.A 10mL graduated cylinder weighs 43.174g.When 5mL of distilled water is measured in it, the combined weight of the graduated cylinder and distilled water is 48.513g.By definition, 5mL of water should weigh 5g.Calculate the weight of the water and express any deviation from 5f as oercentage error. A)0.25% B)0.8% C)0.4% D)0.2% E)1% 118.A graduated cylinder weighs 42.285g.When 10mL of distilled water is measured in it, the combined weight of the graduated cylinder and water is 53.365g.Calculate the weight of water and express any deviation from 10g as percentage error A)1% B)0.08% C)0.8% D)0.4% E)0.04% 119.A pharmacist attempts to weigh 0.425g of morphine sulfate on a balance with dubious accuracy.When checked on a highly accurate balance, the weight is found to be 0.455g.Calcukafe the oercentage error in the first weighing. A)7.06% B)8.13% C)5.52% D)8.12% E)6.07% 120.A vial contains 45mg if a drug in 2mL of injection.How many mL should be administered to obtain 0.015g of drug? A)0.54mL B)0.75mL C)0.49mL D)0.67mL E)1.23mL a quart of liquid weighs 805g, determine the kiquid's specific gravity A)0.17 B)0.85 C)0.95 D)0.57 E)0.63 122.Given the following data, calculate the specific gravity of the unknown liquid: Weight of the empty 25mL pycnometer 60g Weight of the pycnometer + Water 87g Weight of the pycnometer + unknown liquid 83g A)0.28 B)0.77 C)0.97 D)0.85 E)0.64 123.Determine the weight in grams of 543mL alcohol with a specific gravityd of 0.81 A)500.25g B)439.83g C)543.78g D)670.05g E)255.12g 124.Determine the volume in millimeters of 5lb glycerin (specific gravity =1.25) A)1816mL B)2000mL C)473mL D)1250mL E)454mL 125.What is the weight in milligrams of 100mL of liquid petrolatum with a specific gravity of 0.87? A)0.125 B)0.187 C)0.019 D)0.087 E)0.011 126.A pharmacist combines 25mL each of the following: Syrup A specific gravity =1.10 Syrup B specific gravity =1.3 Syrup C specific gravity =1.8 Determine the specific gravity of the combined product. A)4.2 B)3.11 C)1.4 D)0.75 E)1.05 127.A patient was instructed to drink 400mL of barium suspension prior to an abdominal CT scan.If the suspension has a specific graviy of 1.2, calculate the weight of the suspension. A)400g B)480g C)500g D)450g E)120g 128.Express 1:5000 as a percent strength A)0.02% B)0.2% C)0.002% D)2% E)0.0002% 129.Express 0.05 as a ratio strength A)1:1,000 B)1:2,000 C)1:3,000 D)1:500 E)1:10,000 130.An injectable drug contains 5mg of the drug per millimeter of solution.What is the ratio stregth (w/v) of the solution? A)1:500 B)1:5 C)1:200 D)1:2,500 E)1:2,000 131.Express 1:4000 as percent strength A)0.25% B)2.5% C)0.025% D)25% E)0.0025% 132.Express 2.5% as ratio strength. A)1:10 B)1:20 C)1:25 D)1:40 E)1:100 133.Express the following concentration as ratio strength: 3g of active ingredient in 750mL solution A)1:250 B)1:500 C)1:300 D)1:25 E)1:50 134.Express the following concentration as a ratio strength: 0.6mg in 3mL solution A)1:50 B)1:100 C)1:200 D)1:500 E)1:1,000 135.Aneyedrop contains 0.1% of fluorometholone in 5mL solution.What is the amount of fluuorometholone in mg? A)1mg B)5mg C)0.1mg D)0.5mg E)0.005mg 136.A sample of white petrolatum contains 10mg of tocopherol per kilogram as preservative.Express the amount of tocopherol as ratio strength. A)1:50,000 B)1:5,000 C)1:500 D)1:10,000 E)1:1,000 137.Convert 95°F to Celsius A)35°C B)25°C C)70°C D)95°C E)37°C 138.Convert 95°F to Celsius A)35°C B)25°C C)70°C D)95°C E)37°C 139.Convert 68°F to celsius A)20°C B)25°C C)30°C D)70°C E)80°C 140.Convert -10°C to Fahrenheit A)14°F B)22°F C)37°F D)92°F E)12°F 141.Convert 32°Cto Fahrenheit A)89°F B)74°F C)2°F D)77.7°F E)98.6°F 142.Convert 37°C to Fahrenheit A)100°F B)98.6°F C)89.7°F D)2°F E)25°F 143.A 30g tube hemorrhlidaloinment has a following componets in an ointment base: Mineral oil 45%w/ PramoxineHCl 1% w/v Zinc oxide 10%w/v Determine the amount of each component as well as the amount of the ointment base. A)Mineral oil 13.5g PramoxineHCl 0.3g Zinc oxide 3g Ointmebt base 13.2g B)Mineral oil 1.35g PramoxineHCl 0.3g Zinc oxide 3g Ointmebt base 16.8g C)Mineral oil 14.5g PramoxineHCl 0.1g Zinc oxide 1g Ointmebt base 132g D) Mineral oil 13.5g PramoxineHCl 0.03g Zinc oxide 3g Ointmebt base 13.2g E) Mineral oil 135g PramoxineHCl 0.3g Zinc oxide 3g Ointmebt base 13.2g 144.Aneyedropcongains the following: NalhazolineHCl 0.02% w/v Chlorpheniramine maleate 0.25% w/v Bsnzalkoniumchkoride 1:10,000 w/v as preservative Determine the percent strength of benzalkonium chloride and the quantities of each comoonent in 10mL bottle. A)Benzalkonium chloride 0.01% NapthazolineHCl 0.02g Chlorpheniramie maleate 0.125g Benzalkonium chloride 0.001g B)Benzalkonium chloride 0.01% NapthazolineHCl 0.002g Chlorpheniramie maleate 0.025g Benzalkonium chloride 0.001g C) Benzalkonium chloride 0.01% NapthazolineHCl 2g Chlorpheniramie maleate 25g Benzalkonium chloride 1g D) Benzalkonium chloride 0.05% NapthazolineHCl 0.002g Chlorpheniramie maleate 0.25g Benzalkonium chloride 10g E) Benzalkonium chloride 10% NapthazolineHCl 20g Chlorpheniramie maleate 125g Benzalkonium chloride 0.001g 145.Interpret the following: Caps. ip.o.q.d. h.s. A)Takelne capsule by mouth every day at bedtime B)Take two capsule immediately C)Take one capsule by mouth everyday D)Take one tablet at bedtime E)Capsule one by mouth everyday at bedtime 146.Interpret the following gtt. ii o.u q a.m A)Place two drops into both eyes everyday B)Instill two drops into both eyes everyday morning C)Instill two drops into both ears everyday morning D)Place two drops every morning E)Drops two each eye every morning 147.A patient brings a presciption for azithromycin 250mg, quantity 5.Interpret the direction indicated in the prescrioption: Tab ii stat. p.o., then iq.d. x 4 d. A)Take two statistically, then everyday for 4 days B)Take two tablets by mouth everyday for 4 days C) Take two tablets by mouth in the afternoon, the 1 tablet everyday for 4 hours D) Take two tablets by mouth immediately, then 1 tablet everyday for 4 days E) Take two tablets by mouth immediately, then 1 tablet everyday for 4 hours 148.A patient brough the following precsiption to the pharmacy. Rx Losartan 50mg Tablets No. XC Sig. Tabiq AM for HBP If the patient fills this prescription on may 15, when should the patient come back for a refill? A)On or before August 15 same year B)August 15 the following year C)On the last day of August D)On or before June 15 same year E)On or before July 15 same 149.Determine the percent compliance rate if patient received a 30 dya supply of metformin 500mg and returned to the pharmavy in 38days for a refill. A)95.05% B)78.95% C)100% D)97.83% E)75.15% 150.Determine the percent compliance rate if patient received a 90day supply of hydrochloroyhiazide 25mg and returned pharmacy in 92 days for a refill. A)95.05% B)78.95% C)100% D)97.83% E75.15% 151. A patient comes to the pharmacy with the following prescription: Rx Nitroglycerin 0.3 mg SL rep. prn q 5 min up to 3 times; Use at the first sign of angina; seek medical attention if no relief Interpret the directions to the patient. A.) Take one tablet by mouth every 5 minutes as needed, may repeat 3 times. B.) Place one tablet under the tongue, repeat every 5 minutes as needed up to 3 times. C.) Place one tablet subcutaneously as needed, repeat every 5 minutes for up to 3 times. D.) Dissolve one tablet in water and take every 5 minutes as needed up to 3 times. E.) Place one tablet under the tongue, repeat every 5 minutes every day as needed. 152. Interpret the following: Epoetinalfa (Procrit) stat. 50 units/kg SQ 3 x wk. x 3-4 wks. A.) Start Epoetinalfa (Procrit) 50 units/kg subcutaneously immediately, and then 3 times a week for 3 to 4 weeks. B.) Take Epoetinalfa (Procrit) 50 units/kg immediately for 3 weeks, then 3 times a week. C.) Instill Epoetinalfa (Procrit) immediately, then 3 times a week for 3 to 4 weeks. D.) Instill Epoetinalfa (Procrit) subdermally immediately, then 3 times a week for 3 to 4 weeks. E.) Take Epoetinalfa (Procrit) 150 units/kg immediately for 3 weeks, then 3 times a week. 153. If a pint of cough syrup weighs 485 g, what is its specific gravity? A.) 1.125 D.) 1.473 B.) 1.485 E.) 1.003 C.) 1.025 154. If four quarts of substance A weighs 2.75 kg, what is its specific gravity? A.) 0.73 D.) 0.95 B.) 0.82 E.) 1.27 C.) 1.02 155. If a pharmacist adds 15 mL of purified water to 40 mL of a solution with a specific gravity of 1.25, what is the specific gravity of the product? A.) 0.75 D.) 0.97 B.) 1.19 E.) 1.84 C.) 1.02 156. If 250 mL of mineral oil is used to make a quart of mineral oil emulsion, how many grams of the oil would be used to make a gallon of emulsion? (Specific gravity of mineral oil = 0.87) A.) 500.12 g D.) 1892 g B.) 435.11 g E.) 875.43 g C.) 322.56 g 157. Express 8 ppm in ratio strength. A.) 1:250,000 D.) 1:100,000 B.) 1:50,000 E.) 1:800,000 C.) 1:125,000 158. A prefilled syringe of Filgrastim contains 300 mcg/0.5 mL of active ingredient. What is the equivalent concentration of this preparation? A.) 0.06% D.) 6% B.) 6 mg/mL E.) 0.06 mg/mL C.) 3 mg/0.5 mL 159. Rx Ketorolac ophthalmic solution 0.5% Disp. 10 mL Sig. One drop affected eye q.i.d. p.r.n. allergic conjunctivitis This eye drop is available in a dropper container that delivers 15 drops per mL. How many mg of ketorolac is present in each drop of the medication? A.) 0.33 mg D.) 0.55 mg B.) 3.3 mg E.) 5 g C.) 0.33 g 160. A patient with seborrheic dermatitis was prescribed ketoconazole shampoo 2% w/v, to be used weekly for 4 days. If 3 floz of the shampoo will be prepared, how many grams of ketoconazole would be needed to make the shampoo? A.) 2.54 g D.) 1.77 g B.) 29.57 g E.) 177 g C.) 8 g 161. Tafluprost ophthalmic solution contains 0.0015% w/v of active ingredient, available as 0.3 mL preservative-free pouches intended for single use to be instilled into the affected eye. Calculate the number of single use pouches that could be made from 1 g of the drug. A.) 222,222 pouches D.) 2,500 pouches B.) 500,000 pouches E.) 224, 558 pouches C.) 150,870 pouches 162. The formula of 500 mL of an elixir contains 0.1 mL of orange oil as flavor. What is the percent strength of the oil in the elixir? A.) 0.02% D.) 2% B.) 0.5% E.) 2.5% C.) 0.05% 163. A patient brings in a prescription for metronidazole vaginal gel 1.3%. The medication is available in a pre-filled applicator containing 5 g of the gel to be applied as a single dose at bedtime. Determine how much metronidazole is present in one application. A.) 45 mg D.) 35 mg B.) 65 mg E.) 55 mg C.) 75 mg 164. A topical gel contains 1.2% w/w clindamycin phosphate and 0.025% w/w tretinoin. Determine the number of mg of each component present in a 30 g tube. A.) 300 mg clindamycin; 7 mg tretinoin D.) 200 mg clindamycin; 7 mg tretinoin B.) 360 mg clindamycin; 7.5 mg tretinoin E.) 300 mg clindamycin; 5 mg tretinoin C.) 250 mg clindamycin; 6 mg tretinoin 165. If the given dose of a drug is 125 mg, how many doses are in 15 g? A.) 95 doses D.) 150 doses B.) 100 doses C.) 47 doses C.) 120 doses 166. A prescription calls for 1 teaspoonful twice daily of the prescribed medication. How many doses would be contained in 1 pint of the medication? A.) 74 does D.) 22 doses B.) 53 doses E.) 35 doses C.) 47 doses 167. A physician orders 500 mg of ciprofloxacin twice daily for 7 days. What is the total amount in grams of ciprofloxacin that the patient needs to consume to complete the recommended therapy? A.) 7.25 g D.) 7 g B.) 7.6 g E.) 8 g C.) 9 g 168. How many mg of amlodipine besylate and atorvastatin calcium will the patient take for a 30-day supply of the following physician order? Amlodipine besylate/Atorvastatin calcium 5 mg/10 mg x 14 days; then 10 mg/20 mg amlodipine/atorvastatin thereafter. A.) 230mg amlodipine; 460 mg atorvastatin D.) 120mg amlodipine; 320 mg atorvastatin B.) 100mg amlodipine; 200 mg atorvastatin E.) 320mg amlodipine; 460 mg atorvastatin C.) 120mg amlodipine; 412 mg atorvastatin 169. A patient was prescribed varenicline tablets (Chantix) for smoking cessation with the following instructions: 0.5 mg poq.d. x 3 days 0.5 mg po q 12 h x 4 days 1 mg po q 12 h x 11 weeks If this is available as a 0.5 mg and 1 mg tablets, how many 0.5 mg and 1 mg tablets should be dispensed to complete the 12-week therapy? A.) 8 – 0.5 mg tablets; 154 – 1 mg tablets D.) 11 – 0.5 mg tablets; 22 – 1 mg tablets B.) 8 – 0.5 mg tablets; 77 – 1 mg tablets E.) 11 – 0.5 mg tablets; 177 – 1 mg tablets C.) 11 – 0.5 mg tablets; 154 – 1 mg tablets 170. The oral dose of a drug is 5 mg. If a solution contains 2.5% w/v of the drug and is administered with a dropper that delivers 15 drops/mL, how many doses would supply the recommended dose? A.) 3 drops D.) 5 drops B.) 0.2 drops E.) 15 drops C.) 1 drop 171. RimantadineHCl is available as a 50 mg/5 mL syrup. If the recommended dose is 100 mg PO BID x 5 days, how many 5 mL should be dispensed to complete the therapy? A.) 50 mL D.) 200 mL B.) 100 mL E.) 250 mL C.) 150 mL 172. The dose of cefdinir was determined to be 7 mg/kg for a 23 lb patient, to be taken q 12 h for 10 days. If an oral suspension of the drug is available as 25 mg/5 mL, how many mL should be administered to the patient per dose? If the drug is available in both 60 mL and 100 mL bottles, which should be dispensed for this patient that would have the least drug wastage? A.) 3 mL per dose; dispense 60 mL bottle A.) 5 mL per dose; dispense 100 mL bottle B.) 3 mL per dose; dispense 100 mL bottle A.) 12 mL per dose; dispense 100 mL bottle C.) 5 mL per dose; dispense 60 mL bottle 173. The recommended dose of tobramycin for neonate is 5 mg/kg/day given IV or IM divided q 12 h. How many mg of the drug should be given per dose to a 4 lb infant? A.) 4.55 mg per dose D.) 10 mg per dose B.) 9.09 mg per dose E.) 2.2 mg per dose C.) 5 mg per dose 174. A 5-month-old pediatric patient with BSA of 0.85 m2 was prescribed ritonavir with a recommended starting dose of 250 mg/m2 BID. How many mL of the drug should be administered for this patient per day if this is available as a 600 mg/7.5 mL preparation? A.) 1.5 mL per day D.) 2.7 mL per day B.) 5.3 mL per day E.) 6 mL per day C.) 8 mL per day 175. Cabazitaxel is an antineoplastic agent recommended for the management of prostate cancer at a recommended dose of 25 mg/m2 via IV q 3 weeks. What could be the dose in mg for a patient measuring 70 inches in height and weighs 180 lb? A.) 50.3 mg D.) 2 mg B.) 55 mg E.) 81 kg C.) 150.9 mg 176. MP a two-agent dosage regimen for the treatment of multiple myeloma is as follows: Melphalan 0.25 mg/kg PO D 1 – 4 / week x 6 weeks Prednisone 2 mg/kg PO D 1 – 4 / week x 6 weeks Determine the amount in mg of melphalan and prednisone taken per week by a patient who weighs 154 lb. A.) 70 mg melpahalan; 3360 mg prednisone D.) 154 mg melpahalan; 70 mg prednisone B.) 420 mg melpahalan; 560 mg prednisone E.) 210 mg melpahalan; 90 mg prednisone C.) 70 mg melpahalan; 560 mg prednisone 177. If a patient’s weekly dose of prednisone is 560 mg, and the patient prefers to take the oral solution, how many mL of prednisone 5 mg/mL should be dispensed for a 4 week supply of the medication? A.) 2240 mL D.) 112 mL B.) 560 mL E.) 448 mL C.) 240 178. A patient who is being treated for Hodgkin’s lymphoma is taking Procarbazine 100 mg/m2/day PO, D 1 – 14 Prednisone 40 mg/m2/day PO, D 1 – 14 Together with IV doses of Mechloroethamine and Vincristine, the therapy follows a 28-day cycle. Determine the number of 20 mg tablets of prednisone and 50 mg tablets of procarbazine that should be dispensed to a patient with BSA of 1.8 m2 to complete one treatment cycle. A.) 51 tablets procarbazine; 51 tablets prednisone B.) 45 tablets procarbazine; 50 tablets prednisone C.) 140 tablets procarbazine; 560 tablets prednisone D.) 100 tablets procarbazine; 100 tablets prednisone E.) 14 tablets procarbazine; 14 tablets prednisone 179. A breast cancer patient is on monotherapy with docetaxel that is administered 100 mg/m2 IV over 1 hour q 3 weeks. What is the dose for a 5 feet 3 inches patient weighing 150 lb? A.) 115 mg D.) 211 mg B.) 143 mg E.) 155 mg C.) 174 mg 181. A patient being treated with Interferon alfa 2b for malignant melanoma is on a maintenance dose of 10,000,000 units/m2 SC 3 times per week for 48 weeks. If this is supplied as a multi-dose pen, with 6 doses each, which of the following should be used by the patient with BSA 2.08 m2. A.) 22.5 million IU/ 1.5 mL D.) Any of these B.) 37.5 million IU/ 1.5 mL C.) None of these C.) 75 million IU/ 1.5 mL 182. The content of a vial of penicillin G potassium weighs 500 mg which represents 1,000,000 units. How many mg are needed to prepare 1 oz of an ointment that is to contain 15,000 units of penicillin G potassium per gram? A.) 233.1 mg D.) 212.63 mg B.) 425, 250 units E.) 500 mg C.) 400, 000 units 183. A 100 mL vial of alteplase, a thrombolytic drug, contains 100 mg of drug equivalent to 58,000,000 international units to be administered via intravenous infusion. Determine the units administered to a patient who weighs 172 lb at a dose of 0.9 mg/kg and the volume of injection to use. A.) 4,000,000 units; 70.4 mL D.) 7,000,000 units; 80.6 mL B.) 5,000,000 units; 75 mL E.) 8,000,000 units; 9 mL C.) 6,000,000 units; 80 mL 184. A hepatitis B immunoglobulin contains 312 international units per milliliter. If the recommended dose is 0.06 mL/kg for certain at risk individuals, what would be the dose in units and milliliters for a patient who weighs 140 lb? A.) 4.1 mL; 200 IU D.) 5.3 mL; 2000 IU B.) 2.7 mL; 1000 IU E.) 6.1 mL; 1298 IU C.) 3.8 mL; 1191 IU 185. Each milliliter of hepatitis A vaccine (Havrix adult dose) contains 1440 EL. U. (Elisa Units) of viral antigen. Determine the pediatric dose if 720 EL. U. are to be administered. A.) 0.5 mL D.) 0.25 mL B.) 1 mL E.) 2 mL C.) 1.5 mL 186. Diphtheria and tetanus toxoids contain 2 Lf/5 Lf per 0.5 mL. Determine the number of flocculating units of each that is in a 10 mL multi-dose vial. A.) 20 Lf diphtheria; 50 Lf tetanus D.) 10 Lf diphtheria; 50 Lf tetanus B.) 40 Lf diphtheria; 100 Lf tetanus E.) 80 Lf diphtheria; 100 Lf tetanus C.) 80 Lf diphtheria; 200 Lf tetanus 187. Dabigatran (Pradaxa), an anticoagulant used for the prevention of stroke, has the following recommended doses. CrCl 30 mL/min: 150 mg PO BID CrCl 15-30 mL/min: 75 mg PO BID What should be the recommended dose for a 65 year old female patient, weighing 105 lb, and has a serum creatinine of 2 mg/dL. Use the Cockcroft-Gault equation. A.) 150 mg PO BID D.) 75 mg PO QD B.) 150 mg PO QD E.) None of these C.) 75 mg PO BID 188. Rx Soluble silver nitrate 30 mL (E=0.33) 1:250 w/v Make isoton. Sol. Sig. As directed How many grams of potassium nitrate (E=0.58) should be used to make this Rx isotonic? A.) 138.6 mg D.) 132.3 mg B.) 80.4 mg E.) 87.8 mg C.) 95.7 mg 189. Rx Brimonidine tartrate 35 mg (E=0.13) Timolol maleate 80 mg (E=0.14) Chlorobutanol 55 mg (E=0.24) Sodium Chloride qs Purified water qs 20 mL Make isoton. Sol Sig. For the eye How many mg of sodium chloride should be used in compounding the prescription? A.) 151 mg D.) 454 mg B.) 252 mg E.) 555 mg C.) 353 mg 190. Rx Ephedrine HCl 1 g (E=0.29) Chlorobutanol 0.5 g (E=0.24) Dextrose, monohydrate qs Rose water, ad 60 mL Make isoton. Sol. Sig. Nose drops use as directed How many grams of dextrose monohydrate is needed to make the prescription isotonic? A.) 812 mg D.) 610 mg B.) 913 mg E.) 509 mg C.) 711 mg 191. A patient has been prescribed 20 mEq of potassium chloride. How many mEq of KCl would provide this prescribed quantity? A.) 1500 mg D.) 1270 mg B.) 1490 mg E.) 1100 mg C.) 1380 mg 192. A 170 lb patient is prescribed with 4 mEq/kg of sodium chloride. How many mL of half normal saline (0.45% NaCl) should be administered? (MW NaCl = 58.5) A.) 5018 mL D.) 4018 mL B.) 4112 mL E.) 7812 mL C.) 3214 mL 193. An aluminum hydroxide gel suspension contains 320 mg of aluminum hydroxide gel per 5 mL. If a patient is taking 15 mL three times daily between meals and at bed time, how many milliequivalents of aluminum would this patient receive daily? (MW Al(OH)3 = 78) A.) 153 mEq D.) 88 mEq B.) 147 mEq E.) 28.4 mEq C.) 121 mEq 194. A solution contains 20% of anhydrous dextrose in water for injection. How many mOsmol per L are represented by this concentration? (MW of anhydrous dextrose = 180) A.) 1,111 mOsmol/L D.) 2500 mOsmol/L B.) 2,222 mOsmol/L E.) 3,333 mOsmol/L C.) 1500 mOsmol/L 195. Ammonium chloride injection contains 267.5 mg of NH4Cl (MW = 53.5) per mL. How many milliequivalents of NH4Cl are preent in a 10 mL vial? A.) 25 mEq D.) 100 mEq B.) 50 mEq E.) 125 mEq C.) 75 mEq 196. A 20 mL ampule contains 2.98 g potassium chloride. What is the concentration of the solution in mEq per mL? (MW KCl = 74.5) A.) 8 mEq/mL D.) 2 mEq/mL B.) 4 mEq/mL E.) 10 mEq/mL C.) 6 mEq/mL 197. How many milliequivalents of Na+ would be contained in a dose of 50 mL of the following solution: Sodium phosphate, dibasic, heptahydrate (MW = 268) 28 mg Sodium phosphate, monobasic, monohydrate (MW = 138) 58 mg Purified water 100 mL A.) 314.6 mEq D.) 104.5 mEq B.) 223.4 mEq E.) 209 mEq C.) 210.1 mEq 198. A patient is to receive 0.15 mEq of ferrous gluconate per body weight each day divided into three doses. How many milliliters of a ferrous gluconate 300 mg/5 mL syrup should be administered for each dose for a patient who weighs 140 lb? A.) 13.5 mL D.) 17 mL B.) 22.6 mL E.) 21.3 mL C.) 11.8 mL 199. A patient is receiving a slow IV infusion of 30 mEq potassium chloride in 1000 mL of fluid. If, after 10 hours, 500 mL of the infusion have been administered, how many millimoles of KCl were administered? A.) 10 mmol D.) 30 mmol B.) 15 mmol E.) 50 mmol C.) 20 mmol 200. Determine the concentration half NSS (0.45% NaCl) in mmol/L. (MW = 58.5) A.) 75.3 mmol/L D.) 154 mmol/L B.) 76.9 mmol/L E.) 124.3 mmol/L C.) 58.5 mmol/L 201. Determine the concentration of normal saline solution in mmol/L. a. 153.9 mmol/L d. 124.3 mmol/L b. 175.2 mmol/ e. 77.2 mmol/L c. 146.7 mmol/L 202. Determine the total concentration of phosphate in mmol/mL and potassium in mEq/mL in the following preparation: a. 1.71 mmol/mL phosphates; 2.8 mEq/mL K d. 6.41 mmol/mL phosphates; 8.52 mEq/mL K b. 1.42 mmol/mL phosphates; 1.71 mEq/mL K E. 2.04 mmol/mL phosphates; 4.21 mEq/mL k c. 3.07 mmol/mL phosphates; 4.45 mEq/mL K 203. Determine the weekly dose for a 2.5 kg cat, with BSA of 0.18m2, if the recommended dose of methotrexate sodium is 2.5 mg/m3 by mouth given twice weekly. a. 0.45 mg d. 3.5 mg b. 0.9 mg e. 0.18 mg c. 0.35 mg 204. If a 145 lb patient is to be given 40mg/kg of ammonium chloride, how many milliliters of NH4Cl injection containing 3 mEq of NH4Cl per mL should be added to the patient’s IV infusion? (MW = 53.5) a. 20.5 mL d. 8.2 mL b. 16.4 mL e. 24.6 mL c. 10.7 mL 205. A solution contains the following components per 5 mL Potassium acetate (KC2H3O2 – MW 98) 1g Potassium bicarbonate (KHCO3 MW 100) 1g Potassium citrate, monohydrate (K3C6H5O7.H20 – MW 324) 1g What is the total mEq of K+ that are represented in each 5mL solution? a. 29.5 mEq d. 3.4 mEq b. 60 mEq e. 17.4 mEq c. 10.5 mEq 206. How many grams of sodium chloride should be used in preparing 1 gallon of a solution containing 145 mEq/L? (MW NaCl = 58.5) a. 64.22 g d. 54.8 g b. 23.10 g e. 48.82 g c. 32.11 g 207. A patient is given 100 mg of phenytoin sodium (C15H11N2NAO2 – MW= 274) every 8 hours. How many mEq of Na is present in the patient’s daily dose? a. 1.5 mEq d. 1.73 mEq b. 1.22 mEq e. 0.36 mEq c. 1.06 mEq 208. How many grams of sodium bicarbonate (NaHCO3 – MW = 84) should be used in preparing a pint of solution containing 40 mEq per 50 mL? a. 31.8 g d. 42.5 g b. 15.9 g e. 63.2 g c. 47.3 g 209. How many mEq of potassium are in 2,000,000 units of Penicillin V potassium ( C16H17KN2O6S – MW= 388). If one mg of penicillin VK represents 1380 units? a. 4.56 mEq d. 7.21 mEq b. 3.74 mEq e. 2.45 mEq c. 2.31 mEq 210. Rx Potassium chloride 10% Cherry syrup qs ad 240 mL Sig. ii teaspoonful b.i.d. How many mEq of K are represented in each dose? (MW KCL = 74.5) a. 15.5 mEq d. 13.4 mEq b. 26.8 mEq e. 18.7 mEq c. 12.9 mEq 211. If a liter of intravenous fluid contains 10% dextrose and 40 mEq of Na (as NaCl), calculate the percent strength of sodium chloride in the solution. (MW = NaCl = 58.5) a. 0.4% NaCl d. 0.7% NaCl b. 0.10% NaCl e. 0.2% NaCl c. 0.3%NaCl 212. An intravenous solution calls for the addition of 30 mEq of sodium bicarbonate. How many mL of 8.4% w/v sodium bicarbonate injection should be used? (MW NAHCO3 = 84) a. 15 mL d. 10 mL b. 30 mL e. 20 mL c. 25 mL 213. Calcium gluconate( C12H22CaO14 MW = 430) injection 10% is available as 10 mL ampules. How many mEq of calcium would 5 ampules contain? a. 23.26 mEq d. 4.3 mEq b. 4.65 mEq e. 11.63 mEq C. 9.30 mEq 214. A patient has been prescribed with lithium carbonate (Lithobid) (Li2CO3 = MW 74) for the management of bipolar disorder. If the daily dose is four 300 mg tablets, how many milliequivalents of lithium does the patient receive daily? a. 34.23 mEq d. 48.65 mEq b. 16.22 mEq e. 27.54 mEq c. 32.43 mEq 215. Determine how many milligrams of magnesium sulfate (MgSO4 MW = 120) should be added to an IV solution to provide 7 mEq of Mg+2 are present per liter of this solution. a. 420 mg/L d. 120 mg/L B. 840 mg/L e. 72 mg/L c. 210 mg/L 216. Given the following electrolyte solution 200 mg of sodium acetate (NaC2H3O2; MW = 82) and 25 mg of magnesium chloride (MgCl2; MW = 95) in each 100 mL; determine how many mEq of Na and Mg are present per liter of this solution. a. 25.8 mEq/L Na; 15.4 mEq Mg d. 24.4 mEq/L Na; 5.3 mEq Mg b. 14.2 mEq/L Na; 20.3 mEq Mg E. 3 mEq/L Na; 5.3 mEq Mg c. 48.8 mEq/L Na; 2.6 mEq Mg 217. A patient has been prescribed 4 liters of an electrolyte solution containing the following components per 100 mL. 250 mg sodium chloride (NaCl; MW= 58.5) 150 mg potassium acetate (KC2H3O2; MW= 98) 30 mg magnesium acetate (Mg (C2H3O2)2 MW = 142) How many mEq each of Na, K, and Mg does the patient receive? a. 173.2 mEq Na; 61.8 mEq K, and 17.5 mEq Mg b. 123.4 mEq Na; 56.7 mEq K, and 89.1 mEq Mg c. 170.9 mEq Na; 61.2 mEq K, and 16.9 mEq Mg d. 162 mEq Na; 61.5 mEq K, and 19.1 mEq Mg e. 152.3 mEq Na; 59.4 mEq K, and 18.3 mEq Mg 218. A pediatric rehydrating solution contains the following components per liter of solution: Sodium 40 mEq (MW = 23) Potasssium 20 mEq (MW= 39) Chloride 30 mEq (MW 35.5) Citrate 25 mEq (MW =189) Determine how many milligrams of each component is present in a liter of solution. a. 920 mg/L Na; 780 mg/L K; 1065 mg/L chloride; 1575 mg/L citrate b. 972 mg/L Na; 780 mg/L K; 1742 mg/L chloride; 1976 mg/L citrate c. 720 mg/L Na; 580 mg/L K; 1265 mg/L chloride; 1972 mg/L citrate d. 975 mg/L Na; 807 mg/L K; 1084 mg/L chloride; 1575 mg/L citrate e. 856 mg/L Na; 695 mg/L K; 952 mg/L chloride; 1575 mg/L citrate 219. A TPN electrolytes solution contains the following: Calcium chloride 18.2 mg/mL Magnesium chloride 28 mg/mL Potassium chloride 75.4 mg/mL Sodium acetate 123 mg/mL (MW = 82) Sodium chloride 18.5 mg/mL (MW = 58.5) How many mEq of sodium are contained in 10 mL of this solution? a. 21.22 mEq d. 3.16 mEq b. 18.77 mEq e. 12.45 mEq c. 15.61 mEq 220. An electrolyte solution contains 28.3 mg/mL of magnesium chloride (MW = 95). Express the concentration as mmol/L. a. 0.6 mmol/L d. 0.3 mmol/L b. 0.8 mmol/L e. 5 mmol/L c. 0.5 mmol/L 221. A solution contains 330 mg of K ( MW= 39) ions per 1000 mL. How many milliosmoles are represented in the solution? a. 8.5 mOsmol d. 4.2 mOsmol b. 7.2 mOsmol e. 2.1 mOsmol c. 3.4 mOsmol 222. A parenteral solution contains 4 mEq/mL of potassium acetate ( MW = 98), calculate the osmolarity in milliosmoles per liter. a. 8,000 mOsmol/L d. 1,000 mOsmol/L b. 4,000 mOsmol/L e. 500 mOsmol/L c. 2,000 mOsmol/L 223. A solution contains 5% anhydrous dextrose in water for injection. Determine the milliosmoles per liter represented by this solution. a. 277.8 mOsmol/L d. 145.2 mOsmol/L b. 138.9 mOsmol/L e. 115.3 mOsmol/L c. 245.8 mOsmol/L 224. A pharmacist receives an order to prepare 100 mL of a solution containing 40 mOsmol of calcium chloride. How many grams of calcium chloride would be needed to prepare this solution? Assume complete dissociation. ( MW CaCl2 = 111) a. 2.56 g d. 4.44g b. 1.48g e. 2.22 g c. 3.20 g 225. Determine the osmolarity of 1000 mL of a solution containing 5% w/v dextrose (MW =180), 0/45% sodium chloride (MW = 58.5), and 10 mEq of calcium gluconate (MW = 430) a. 223.32 mOsmol/L d. 558.29 mOsmol/L b. 446.63 mOsmol/L e. 668.30 mOsmol/L c. 111.66 mOsmol/L 226. A parenteral solution contains 10% w/w sodium bicarbonate (MW= 84) per 1000 mL. Determine the mEq/mL, total mEq, and osmolarity of the solution. a. 2 mEq/L; 2000 mEq; 2500.11 mOsmol/L b. 1.7 mEq/L; 2000 mEq; 345.03 mOsmol/L c. 2 mEq/L; 1190 mEq; 233.45 mOsmol/L d. 1.19 mEq/L; 1190 mEq; 2380.95 mOsmol/L e. 1.5 mEq/L; 1300 mEq; 2400.01 mOsmol/L 227. A patient has an order for 80 g of mannitol( MW= 182), an osmotic diuretic, to be administered over a 24-hour period. If what the pharmacy has on hand is 15% w/v mannitol injection, how many milliliter should be administered per hour? How many milliosmoles of mannitol would be represented by the prescribed dosage? a. 22.2 mL/hr; 439.6 mOsmol d. 27.2 mL/hr; 512.2 mOsmol b. 80 mL/hr; 182 mOsmol e. 33.3 mL/hr; 660.5 mOsmol c. 11.2 mL/hr; 220.4 mOsmol 228. A colon lavage preparation contains the following mixture of dry powder in each packet to prepare one gallon of solution: Sodium sulfate 22 g (MW = 142) Sodium chloride 5.2g (MW = 58.5) Potassium chloride 2.5 g (MW= 74.5) Sodium bicarbonate 6.4 g (MW= 84) Polyethylene glycol (PEG 3350) 230.1 g Determine the milliequivalents each of sodium and chloride present in the prepared solution. a. 317.5 mEq Na; 135.1 mEqCl d. 452.1 mEq Na; 122.5 mEqCl b. 376.5 mEq Na; 145.1 mEqCl e. 474.9 mEq Na; 112.4 mEqCl c. 474.9 mEq Na; 122.5 mEqCl 229. A 500 mL IV bag contains 0.15% sodium chloride and 2% dextrose. How many grams of each are present in the solution? a. 0.15 g NaCl; 2g dextrose d. 1g NaCl; 20 g dextrose b. 0.75g NaCl; 10g dextrose e. 1.5 g NaCl; 20 g dextrose c. 2g NaCl; 75 g dextrose 230. A patient received 750 mL of D5W ½ NS at a rate of 20 drops per minute. If the administration set used delivers 20 drops/mL calculate infusion time in hours, minutes. a. 12 hours, 30 minutes d. 12 hours, 50 minutes b. 12 hours, 5 minutes e. 7 hours, 30 minutes c. 7 hours, 50 minutes 231. A pediatric patient received 100 mL of an infusion at 10 drops per minute with an administration set that delivered 60 drops per mL. Determine the duration of the infusion in minutes. a. 12 hours d. 60 hours b. 10 hours e. 5 hours c. 8 hours 232. Determine the total time, in minutes, to complete the infusion of an IV drip containing 3g of lidocaineHCl that is administered 6 mg/min. a. 100 minutes d. 87 minutes b. 45 minutes e. 10 minutes c. 500 minutes 233. A 170 lb patient is recommended to receive daptomycin 50 mg/kg in 0.9% NaCl to be administered via IV infusion over a 30 minute period. How many mL of a vial containing 500 mg/mL should be added to a 100 mL bag of normal saline? a. 8 mL d. 6.21 mL b. 9.15 mL e. 9.33 mL c. 7.73 mL 234. A patient weighing 150 lb has an order for an IV infusion containing amikacin sulfate 7.5 mg/kg of body weight to be added to 250 mL of D5W. What is available in the pharmacy is amikacin sulfate injection 500mg/2mL, how many mL should be used to prepare the infusion? a. 1 mL d. 3 mL b. 2 mL e. 2.5 mL c. 1.5 mL 235. A 22lb pediatric patient’s medication orders include vancomycin 10mg/kg, to be administered via IV infusion. The pharmacy only has 500 mg vancomycin per 10 mL injection available on hand. The pharmacist adds the correct amount to a 100 mL bag of NSS. How many mL of the injection were added and what is the content (mg/mL) of vancomycin in the infusion? a. 4.6 mL vancomycin inj.; 1.22 mg/mL d. 2.3 mL vancomycin inj.; 1.11 mg/mL b. 6.9 mL vancomycin inj.; 2.13 mg/mL e. 2.7 mL vancomycin inj.; 3.15 mg/mL c. 5.2 mL vancomycin inj.; 3.2 mg/mL 236. A physician orders 5 L of IV fluids for a patient to be administered over 24 hours using an IV set that delivers 15 drops/mL. Calculate the drip rate in drops per minute and mL/hour. a. 25 drops/minute; 105mL/hr d. 75 drops/ minute; 240 mL/hr b. 32 drops/minute; 125.5 mL/hr e. 65 drops/ minute; 252.7 mL/hr c. 52 drops/minute; 208.33 mL/hr 237. A medication order indicates 300 mg of drug to be added to 500 mL D5W. Determine the volume, in mL, of a 1g/5mL preparation of the drug to be used to prepare the solution. If this is administered at a rate of 1.5 mL/min, how many mg of the drug would the patient receive in 1 hour? a. 1.5mL; 54 mg d. 3mL; 108 mg b. 1.5 mL; 300 mg e. 2 mL; 27 mg c. 5mL; 54 mg 238. The drug labelatol is indicated on the medication order of a patient and is administered at a rate of 2 mg/min via continuous IV infusion, with a dose of 300 mg in 300 mL of solution. If an infusion set that delivers 15 drops/mL is used, what would be the required drip rate for this patient? a. 15 drops/ minute d. 60 drops/minute b. 30 drops/minute e. 75 drops/minute c. 45 drops/minute 239. A patient is receiving 500 mL of an IV drip containing 20,000 units of heparin sodium in sodium chloride injection. Determine the administration rate, mL/hr to deliver 1100 units of sodium heparin per hour and the administration rate, drops/minute, with an IV set that delivers 20 drops/mL. a. 30.2 mL/hr; 8 drops/min d. 27.5 mL/hr; 9 drops/min b. 22 mL/hr; 7 drops/min e. 35 mL.hr; 11 drops/min c. 33mL/hr; 8 drops/min 240. A patient’s medication order indicates that a drug be infused at a rate of 4mg/hr for 12 hours. The drug is available in 10 mL vials containing 10 mg of the drug per mL. If a 250 mL bottle of D5W is used as the vehicle, how many mL of the drug should be added and what should be the flow rate in mL/minute? a. 4.8 mL should be added; 0.35 mL/min d. 8.4 mL should be added; 0.25 mL/min b. 9.2 mL should be added; 0.55 mL/min e. 3.5 mL should be added; 0.11 mL/min c. 5.2 mL should be addes; 0.76 mL/min 241.