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MRCP PART 1 HAEMATOLOGY AND ONCOLOGY Exam Questions and answers
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MRCP PART 1 HAEMATOLOGY AND ONCOLOGY Exam Questions and answers What is the most commonly inherited thrombophilia? - Factor V Leiden What causes facor V leiden? - mutation in factor V resulting in resistance in inactivation of protein C What does protein C do? - inhibits co-factors FVa and FVIIIa What does protein S do? - combines with activated protein C to inhibit co-factors FVa and FVIIIa What does antithrombin III do? - inhibits clotting factors such as FVIIa (thrombin) and FXa What does Von Willebrand factor do? - it is a transporter for FVIII in the blood and acts as a binding surface on damaged endothelium for plateltets
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