APMLE Practice Test Questions With Complete Solutions
2-PAM (pralidoxime) Correct Answers allows
acetylcholinesterase to function again. Used as an antidote in
cholinesterase inhibitor poisoning to free up the blocked enzyme
So reactivates acetylcholinesterase
3rd layer plantar muscles Correct Answers flexor hallucis
brevis, adductor hallucis, flexor digiti minimi brevis
They all insert on the proximal phalanges
5-fluorouracil Correct Answers inhibits thymidylate synthase
A common adverse effect of prolonged therapy with
hydrochlorothiazide is Correct Answers Hyperuricemia
Thiazides compete with uric acid and displace it from its binding
site, resulting in the development of hyperuricemia
A decrease in albumin concentration in the blood would be
expected to Correct Answers Decrease magnitude of osmotic
gradient for fluid flow back into the capillary, thereby increasing
the tendency for fluid to flow out of the capillary
A green-tinged pus or exudate is usually indicative of infection
with which bacteria Correct Answers P aeruginosa
A hyperpyrexic come can result from an interaction between
meperidine and ____ Correct Answers MAO inhibitor
A patient presents with a cutaneous ulcer that began as a
vesicular lesion and became pustular before ulceration. A
,scraping of the ulcer reveals intranuclear inclusion bodies. Most
likely diagnosis is Correct Answers Herpes
A patient with a long history of alcohol abuse is most likely to
develop which type of heart disease? Correct Answers Dilated
cardiomyopathy
A patient with drooping of the right side of the mouth and
unable to close right eye tightly is due to Correct Answers
Facial nerve damage
Absorption of drugs depend on Correct Answers Passive
transfer
Rate of diffusion
Lipid solubility of the drug
Absorption of tetracycline is inhibited by what Correct Answers
Multivalent cations like Ca, Mg, and Al
Diary products and antacids with multivalent cations
Acetyl-CoA enters the Karen cycle via Correct Answers OAA
Acetylcysteine is used to prevent what Correct Answers
Hepatotoxicity after an acute overdose of acetaminophen
Acid fast staining is characteristic of which bacteria species?
Correct Answers Mycobacterium
ACTH primarily stimulates the release of Correct Answers
Cortisol
,actinic keratosis Correct Answers precancerous skin condition
of horny tissue formation that results from excessive exposure to
sunlight
Activation of the vagus nerve affect the heart in what way?
Correct Answers An increased P-R interval
Acute inflammation Correct Answers Response to injury that
causes the release of many factors from both injured cells and
inflammatory cells
Blood flow increases and more leaking occurs, which causes
proteinaceous edema
Neutrophils migrate out of vessels into the interstitial space to
clean up the injured cell debris or infectious agent
It is short duration
adductor tubercle of femur Correct Answers projection on the
medial surface of the medial epicondyle - for attachment of
adductor magnus
Alkalinization of the glomerular filtrate enhances Correct
Answers H+ ion secretion, weak acid secretion
Alpha adrenergic agonist Correct Answers Phenylephrine
Alpha adrenergic antagonist Correct Answers prazosin
-blocks alpha 1 adrenergic receptors causing vasodilation
-increased incidence of HF
-not first line agents
, Amantidine A Correct Answers inhibits fusion of viral particles
within endosome of the cell
For influenza A
Amiloride Correct Answers K-sparing diuretic.
Can lead to hyperkalemia
Aminoglycosides toxicity Correct Answers Nephrotoxicity
(especially when used with cephalosporins)
Neuromuscular blockade
Ototoxicity (especially when used with loop diuretics)
Teratogen.
An increase in the force of a whole skeletal muscle is achieved
by the recruitment of Correct Answers More motor units
anaplasia Correct Answers loss of differentiation of cells;
reversion to a more primitive cell type
Permanent , irreversible change
Angle formed by long axis of the femoral neck and the long axis
of the femoral shaft is referred to as Correct Answers Angle of
inclination
Between 120-125
Antigenic drift Correct Answers a mechanism for variation in
viruses that involves the accumulation of mutations within the
genes that code for antibody-binding sites.
Antigenic shift Correct Answers changes in antigens that occur
when viruses exchange genetic material with other strains
2-PAM (pralidoxime) Correct Answers allows
acetylcholinesterase to function again. Used as an antidote in
cholinesterase inhibitor poisoning to free up the blocked enzyme
So reactivates acetylcholinesterase
3rd layer plantar muscles Correct Answers flexor hallucis
brevis, adductor hallucis, flexor digiti minimi brevis
They all insert on the proximal phalanges
5-fluorouracil Correct Answers inhibits thymidylate synthase
A common adverse effect of prolonged therapy with
hydrochlorothiazide is Correct Answers Hyperuricemia
Thiazides compete with uric acid and displace it from its binding
site, resulting in the development of hyperuricemia
A decrease in albumin concentration in the blood would be
expected to Correct Answers Decrease magnitude of osmotic
gradient for fluid flow back into the capillary, thereby increasing
the tendency for fluid to flow out of the capillary
A green-tinged pus or exudate is usually indicative of infection
with which bacteria Correct Answers P aeruginosa
A hyperpyrexic come can result from an interaction between
meperidine and ____ Correct Answers MAO inhibitor
A patient presents with a cutaneous ulcer that began as a
vesicular lesion and became pustular before ulceration. A
,scraping of the ulcer reveals intranuclear inclusion bodies. Most
likely diagnosis is Correct Answers Herpes
A patient with a long history of alcohol abuse is most likely to
develop which type of heart disease? Correct Answers Dilated
cardiomyopathy
A patient with drooping of the right side of the mouth and
unable to close right eye tightly is due to Correct Answers
Facial nerve damage
Absorption of drugs depend on Correct Answers Passive
transfer
Rate of diffusion
Lipid solubility of the drug
Absorption of tetracycline is inhibited by what Correct Answers
Multivalent cations like Ca, Mg, and Al
Diary products and antacids with multivalent cations
Acetyl-CoA enters the Karen cycle via Correct Answers OAA
Acetylcysteine is used to prevent what Correct Answers
Hepatotoxicity after an acute overdose of acetaminophen
Acid fast staining is characteristic of which bacteria species?
Correct Answers Mycobacterium
ACTH primarily stimulates the release of Correct Answers
Cortisol
,actinic keratosis Correct Answers precancerous skin condition
of horny tissue formation that results from excessive exposure to
sunlight
Activation of the vagus nerve affect the heart in what way?
Correct Answers An increased P-R interval
Acute inflammation Correct Answers Response to injury that
causes the release of many factors from both injured cells and
inflammatory cells
Blood flow increases and more leaking occurs, which causes
proteinaceous edema
Neutrophils migrate out of vessels into the interstitial space to
clean up the injured cell debris or infectious agent
It is short duration
adductor tubercle of femur Correct Answers projection on the
medial surface of the medial epicondyle - for attachment of
adductor magnus
Alkalinization of the glomerular filtrate enhances Correct
Answers H+ ion secretion, weak acid secretion
Alpha adrenergic agonist Correct Answers Phenylephrine
Alpha adrenergic antagonist Correct Answers prazosin
-blocks alpha 1 adrenergic receptors causing vasodilation
-increased incidence of HF
-not first line agents
, Amantidine A Correct Answers inhibits fusion of viral particles
within endosome of the cell
For influenza A
Amiloride Correct Answers K-sparing diuretic.
Can lead to hyperkalemia
Aminoglycosides toxicity Correct Answers Nephrotoxicity
(especially when used with cephalosporins)
Neuromuscular blockade
Ototoxicity (especially when used with loop diuretics)
Teratogen.
An increase in the force of a whole skeletal muscle is achieved
by the recruitment of Correct Answers More motor units
anaplasia Correct Answers loss of differentiation of cells;
reversion to a more primitive cell type
Permanent , irreversible change
Angle formed by long axis of the femoral neck and the long axis
of the femoral shaft is referred to as Correct Answers Angle of
inclination
Between 120-125
Antigenic drift Correct Answers a mechanism for variation in
viruses that involves the accumulation of mutations within the
genes that code for antibody-binding sites.
Antigenic shift Correct Answers changes in antigens that occur
when viruses exchange genetic material with other strains
