APMLE Part 1 USMLE Comprehensive Review Questions
With Complete Solutions
. Duodenum (all but the first part) 2. Ascending Colon 3. Ureters
4. Pancreas 5. Supra renal glands (adrenals) 6. Descending colon
7. Aorta 8. Kidneys 9. Rectum 10. IVC D CUPS DAKRI is the
mnemonic, everything else is covered with peritoneum Correct
Answers Name the 10 retroperitoneal organs.
"Lady between two Majors": latissimus dorsi, pectoralis major,
and teres major Correct Answers What muscles insert in or on
the intertubercular groove of the humerus?
(MA/CA) x 100 = IQ score, where MA = mental age and CA =
chronological age Correct Answers What is the formula to
calculate IQ?
>10 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • IV drug abuser
>10 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • Recent immigrant from India
>15 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • Healthy suburban male
without any medical illnesses
>5 mm Correct Answers What is the size of a positive PPD test
for the following? (Reactive) • Patient with AIDS
,>5 mm Correct Answers What is the size of a positive PPD test
for the following? (Reactive) • Posttransplantation patient taking
immunosuppressive agents
1. 7-methyl guanine cap on the 5' end 2. Addition of the poly(A)
tail to the 3' end 3. Removal of introns Correct Answers What
are the three posttranscriptional modifications?
1. Benefits of the procedure 2. Purpose of the procedure 3. Risks
of the procedure 4. The nature of the procedure (what you are
doing) 5. The alternative to this procedure and its availability
(Don't forget the last one; this is where physicians get in
trouble.) Correct Answers What are the five pieces of
information considered necessary for fully informed consent?
1. Bunyavirus 2. Orthomyxovirus 3. Arenavirus 4. Reovirus
Remember BOAR Correct Answers What are the four
segmented RNA viruses?
1. Burkitt's lymphoma 2. Nasopharyngeal carcinoma 3. Thymic
carcinoma Correct Answers What three carcinomas are
associated with EBV?
1. C5a 2. Leukotriene B4 3. IL-8 4. Bacterial peptides Correct
Answers What are the four chemotactic agents?
1. Ca2+ : calmodulin ratio 2. Epinephrine 3. Glucagon Correct
Answers What three substances stimulate glycogenolysis?
1. Cortisol (stimulates PEPCK) 2. Glucagon 3. GTP Correct
Answers What three substrates control the enzyme PEPCK for
,the conversion of oxaloacetate (OAA) to pyruvate in the
cytoplasm?
1. Cough 2. Coryza 3. Conjunctivitis Correct Answers What are
the three C's of measles?
1. Covalent bonding between the hapten and carrier 2. B-cell
exposure to hapten twice 3. T-cell exposure to carrier twice
Correct Answers What are the three rules governing a
secondary immune response?
1. Cytosine 2. Uracil (only in RNA) 3. Thymidine Correct
Answers What three bases are pyrimidines?
1. Cytotrophoblast 2. Syncytiotrophoblast 3. Extraembryonic
mesoderm Correct Answers What three embryonic cell layers
form the chorion?
1. Decrease concentrations of Ag levels 2. Administer IgG in
high concentrations 3. Inhibit B cells with Ag bound to IgG
(complexes) 4. Turn off the original T or B cell with anti-Ab
Correct Answers What are the four ways to down-regulate the
immune system?
1. Dorsal scapular 2. Suprascapular 3. Long thoracic 4. Nerve to
subclavius Correct Answers What four branches of the brachial
plexus arise prior to the first rib?
1. Epinephrine synthesis 2. Phosphatidyl choline 3. Creatine 4.
Methylation of cytosine 5. N-methyl cap of mRNA Correct
, Answers What five pathways use SAM (S-adenosylmethionine)
as the methyl donor?
1. Fructokinase 2. Glucokinase 3. Glycerol kinase 4. PEPCK 5.
Pyruvate carboxylase 6. Galactokinase 7. Fructose-1, 6-
bisphosphatase 8. Glucose-6-phosphatase Correct Answers
What are the eight liver-specific enzymes?
1. Fructose-6-phosphate 2. Glucose-6-phosphate 3.
Glyceraldehyde-3-phosphate Correct Answers At what three
sites can the HMP shunt enter into glycolysis?
1. Glucagon 2. NADH 3. Acetyl CoA 4. ATP Correct Answers
What four substances increase the rate of gluconeogenesis?
1. Glucose from liver glycogen 2. Glucose from
gluconeogenesis 3. Body protein 4. Body fat Correct Answers
What is the order of fuel use in a prolonged fast?
1. Glycine 2. Aspartate 3. Glutamine Correct Answers What
three AAs are used to synthesize the purine ring?
1. H2O2 2. Superoxide 3. Hydroxyl radical 4. Myeloperoxidase
5. Hypochlorous acid Correct Answers What five main
oxidizing reactions are used to kill ingested organisms?
1. IgA receptor 2. Transport of IgA across epithelial barriers 3.
Protection of IgA from degradative proteases Correct Answers
What are the three major functions of secretory IgA?
With Complete Solutions
. Duodenum (all but the first part) 2. Ascending Colon 3. Ureters
4. Pancreas 5. Supra renal glands (adrenals) 6. Descending colon
7. Aorta 8. Kidneys 9. Rectum 10. IVC D CUPS DAKRI is the
mnemonic, everything else is covered with peritoneum Correct
Answers Name the 10 retroperitoneal organs.
"Lady between two Majors": latissimus dorsi, pectoralis major,
and teres major Correct Answers What muscles insert in or on
the intertubercular groove of the humerus?
(MA/CA) x 100 = IQ score, where MA = mental age and CA =
chronological age Correct Answers What is the formula to
calculate IQ?
>10 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • IV drug abuser
>10 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • Recent immigrant from India
>15 mm Correct Answers What is the size of a positive PPD
test for the following? (Reactive) • Healthy suburban male
without any medical illnesses
>5 mm Correct Answers What is the size of a positive PPD test
for the following? (Reactive) • Patient with AIDS
,>5 mm Correct Answers What is the size of a positive PPD test
for the following? (Reactive) • Posttransplantation patient taking
immunosuppressive agents
1. 7-methyl guanine cap on the 5' end 2. Addition of the poly(A)
tail to the 3' end 3. Removal of introns Correct Answers What
are the three posttranscriptional modifications?
1. Benefits of the procedure 2. Purpose of the procedure 3. Risks
of the procedure 4. The nature of the procedure (what you are
doing) 5. The alternative to this procedure and its availability
(Don't forget the last one; this is where physicians get in
trouble.) Correct Answers What are the five pieces of
information considered necessary for fully informed consent?
1. Bunyavirus 2. Orthomyxovirus 3. Arenavirus 4. Reovirus
Remember BOAR Correct Answers What are the four
segmented RNA viruses?
1. Burkitt's lymphoma 2. Nasopharyngeal carcinoma 3. Thymic
carcinoma Correct Answers What three carcinomas are
associated with EBV?
1. C5a 2. Leukotriene B4 3. IL-8 4. Bacterial peptides Correct
Answers What are the four chemotactic agents?
1. Ca2+ : calmodulin ratio 2. Epinephrine 3. Glucagon Correct
Answers What three substances stimulate glycogenolysis?
1. Cortisol (stimulates PEPCK) 2. Glucagon 3. GTP Correct
Answers What three substrates control the enzyme PEPCK for
,the conversion of oxaloacetate (OAA) to pyruvate in the
cytoplasm?
1. Cough 2. Coryza 3. Conjunctivitis Correct Answers What are
the three C's of measles?
1. Covalent bonding between the hapten and carrier 2. B-cell
exposure to hapten twice 3. T-cell exposure to carrier twice
Correct Answers What are the three rules governing a
secondary immune response?
1. Cytosine 2. Uracil (only in RNA) 3. Thymidine Correct
Answers What three bases are pyrimidines?
1. Cytotrophoblast 2. Syncytiotrophoblast 3. Extraembryonic
mesoderm Correct Answers What three embryonic cell layers
form the chorion?
1. Decrease concentrations of Ag levels 2. Administer IgG in
high concentrations 3. Inhibit B cells with Ag bound to IgG
(complexes) 4. Turn off the original T or B cell with anti-Ab
Correct Answers What are the four ways to down-regulate the
immune system?
1. Dorsal scapular 2. Suprascapular 3. Long thoracic 4. Nerve to
subclavius Correct Answers What four branches of the brachial
plexus arise prior to the first rib?
1. Epinephrine synthesis 2. Phosphatidyl choline 3. Creatine 4.
Methylation of cytosine 5. N-methyl cap of mRNA Correct
, Answers What five pathways use SAM (S-adenosylmethionine)
as the methyl donor?
1. Fructokinase 2. Glucokinase 3. Glycerol kinase 4. PEPCK 5.
Pyruvate carboxylase 6. Galactokinase 7. Fructose-1, 6-
bisphosphatase 8. Glucose-6-phosphatase Correct Answers
What are the eight liver-specific enzymes?
1. Fructose-6-phosphate 2. Glucose-6-phosphate 3.
Glyceraldehyde-3-phosphate Correct Answers At what three
sites can the HMP shunt enter into glycolysis?
1. Glucagon 2. NADH 3. Acetyl CoA 4. ATP Correct Answers
What four substances increase the rate of gluconeogenesis?
1. Glucose from liver glycogen 2. Glucose from
gluconeogenesis 3. Body protein 4. Body fat Correct Answers
What is the order of fuel use in a prolonged fast?
1. Glycine 2. Aspartate 3. Glutamine Correct Answers What
three AAs are used to synthesize the purine ring?
1. H2O2 2. Superoxide 3. Hydroxyl radical 4. Myeloperoxidase
5. Hypochlorous acid Correct Answers What five main
oxidizing reactions are used to kill ingested organisms?
1. IgA receptor 2. Transport of IgA across epithelial barriers 3.
Protection of IgA from degradative proteases Correct Answers
What are the three major functions of secretory IgA?
