NURS 535 Practice –Foundations of
Pharmacology-Exam with Verified
Answers
Clinical Practice Guidelines - ✔✔Summarize literature for clinician accessibility.
Guideline Development Considerations - ✔✔Include evidence, grade quality, synthesize
meaningfully.
GRADE Working Group - ✔✔Recommends implementation, evaluation, and updating
guidelines.
Guideline Update Frequency - ✔✔Guidelines should be updated every 3 years.
Bioavailability (F) - ✔✔Rate and extent of drug absorption.
Factors Affecting Bioavailability - ✔✔Includes food/drug interactions and GI motility.
Clearance - ✔✔Rate at which the body eliminates a drug.
Hepatic Metabolism - ✔✔Liver primarily metabolizes drugs.
Renal Excretion - ✔✔Kidneys filter and secrete drugs and metabolites.
Cockcroft-Gault Equation - ✔✔Uses serum creatinine to estimate kidney function.
, Volume of Distribution - ✔✔Extent of drug distribution into tissues.
Loading Dose - ✔✔Higher for drugs with large volume of distribution.
Elimination Rate (K) - ✔✔Measures drug elimination per unit time.
Half-Life (t1/2) - ✔✔Time taken for drug concentration to halve.
Rapid Elimination - ✔✔Shorter half-life for drugs eliminated quickly.
Pharmacodynamics - ✔✔Effects of drugs on tissues and organs.
First-Pass Metabolism - ✔✔Drug metabolism in GI tract and liver.
IV Administration - ✔✔Intravenous route for immediate drug effect.
Pharmacokinetics - ✔✔Study of drug absorption, distribution, metabolism, excretion.
Pharmacokinetic Parameters - ✔✔Key metrics include bioavailability, clearance, volume of
distribution.
Clinical Practice Guideline Examples - ✔✔USPTF, ACG, AAFP are notable examples.
Evidence-Based Practice - ✔✔Using research evidence to guide clinical decisions.
Pharmacogenetics - ✔✔Genetic variation in drug response at gene level.
Pharmacology-Exam with Verified
Answers
Clinical Practice Guidelines - ✔✔Summarize literature for clinician accessibility.
Guideline Development Considerations - ✔✔Include evidence, grade quality, synthesize
meaningfully.
GRADE Working Group - ✔✔Recommends implementation, evaluation, and updating
guidelines.
Guideline Update Frequency - ✔✔Guidelines should be updated every 3 years.
Bioavailability (F) - ✔✔Rate and extent of drug absorption.
Factors Affecting Bioavailability - ✔✔Includes food/drug interactions and GI motility.
Clearance - ✔✔Rate at which the body eliminates a drug.
Hepatic Metabolism - ✔✔Liver primarily metabolizes drugs.
Renal Excretion - ✔✔Kidneys filter and secrete drugs and metabolites.
Cockcroft-Gault Equation - ✔✔Uses serum creatinine to estimate kidney function.
, Volume of Distribution - ✔✔Extent of drug distribution into tissues.
Loading Dose - ✔✔Higher for drugs with large volume of distribution.
Elimination Rate (K) - ✔✔Measures drug elimination per unit time.
Half-Life (t1/2) - ✔✔Time taken for drug concentration to halve.
Rapid Elimination - ✔✔Shorter half-life for drugs eliminated quickly.
Pharmacodynamics - ✔✔Effects of drugs on tissues and organs.
First-Pass Metabolism - ✔✔Drug metabolism in GI tract and liver.
IV Administration - ✔✔Intravenous route for immediate drug effect.
Pharmacokinetics - ✔✔Study of drug absorption, distribution, metabolism, excretion.
Pharmacokinetic Parameters - ✔✔Key metrics include bioavailability, clearance, volume of
distribution.
Clinical Practice Guideline Examples - ✔✔USPTF, ACG, AAFP are notable examples.
Evidence-Based Practice - ✔✔Using research evidence to guide clinical decisions.
Pharmacogenetics - ✔✔Genetic variation in drug response at gene level.
