NUR 354 Exam 2 Study Questions with
Correct Answers Graded A+ 2025-2026
What drug class do furosemide and bumetanide fall under?
loop diuretics
what is the pharmacological action of loop diuretics?
- block reabsorption of sodium, chloride, and water in the loop of Henle
Which diuretic class still works well in kidney impairment?
loop diuretics
What are the therapeutic uses associated with loop diuretics?
- reduce edema from HF, cirrhosis, and renal failure
- can be used to temporarily treat hypertension from FVE
What are the drug interactions associated with loop diuretics?
- hypokalemia risk: may cause dysrhythmias with digoxin and cardiac glycosides
(heart failure meds)
- caution with meds that are nephrotoxic or ototoxic like opioids and amino-
glycoside antibiotics
- may counteract insulin and cause hyperglycemia due to increased blood
concentration
What are the food interactions associated with loop diuretics?
- hawthorn= hypotension
- ginseng and high sodium reduce effectiveness
What side effects are associated with loop diuretics?
- hypokalemia and other electrolyte imbalances
- dehydration
- hypotension
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- hypovolemia
What adverse effects are associated with loop diuretics?
- ototoxicity: tinitus, vertigo, nausea
- hyperglycemia
- hyperuricemia
- increased LDL and decreased HDL
What are some nursing interventions for loop diuretics?
- obtain baseline data: vitals, i's&o's, amount and placement of edema, lung
sounds, skin turgor, mucus membrane assessment
- daily weights at same time each day
- monitor electrolyte levels
- monitor BP and HR/pulses before administration
What are some safety considerations for loop diuretics?
tell provider if any of these symptoms develop: dry mouth, increased thirst, muscle
cramps, n/v,
symptoms of orthostatic hypotension such as dizziness, lightheadedness, and
syncope may occur
What should you educate patients on if they are receiving loop diuretics?
- change positions slowly
- tell provider if signs of dehydration or electrolyte imbalance occur
How should you evaluate for loop diuretic effectiveness?
daily weights, i's&o's, electrolyte levels, kidney function monitoring (serum
creatinine and serum BUN)
What drug class is hydrochlorothiazide in?
thiazide diuretic
What is the pharmacological action of thiazide diuretics?
blocks sodium, chloride, and water reabsorption in the kidney tubule which
encourages potassium and water excretion
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