CVS PHARMACOLOGY ACTUAL EXAMS 2026 (2
DIFFERENT VERSIONS) | CARDIOVASCULAR
SYSTEM PHARMACOLOGY EXAM | ALL QUESTIONS
AND CORRECT ANSWERS | UPDATED VERSIONS
CVS Pharmacology Exam (First Version)
What is the MOA of alpha 1 agonists? ---------CORRECT ANSWER-----------
-------Increase alpha 1 activity. alpha 1 agonist, increase BP, -direct
topical doses causes vasoconstriction through direct alpha 1 effects in
nose.
-Mimics the effect of NA and Adrenaline on alpha -1 in vascular smooth
muscle.
What are the therapeutic uses of alpha 1 agonists? ---------CORRECT
ANSWER------------------Used as local decongestants in the nose and
conjunctivitis. Allergy rhinitis. Can also be taken systemically.
-treat allergies
-treat common colds
,What are the side effects of phenylephrine? ---------CORRECT ANSWER--
---------------rebound nasal congestion.
especially with topical version.
What are the contraindications of alpha 1 agonists? ---------CORRECT
ANSWER-----------------Contraindicated in uncontrolled hypertension.
Give examples of a alpha 1 agonists. ---------CORRECT ANSWER------------
-----Phenylephrine (topical and oral)
Ephedrine.
adrenalin.
What is the MOA of phenylephrine? ---------CORRECT ANSWER-------------
----direct alpha 1 agonist.
What is the MOA of ephedrine? ---------CORRECT ANSWER-----------------
causes release of both NA & A.
,What is the MOA of adrenaline? ---------CORRECT ANSWER-----------------
it is a direct alpha 1, beta 1 and beta 2 agonist.
-Increase conduction through AV node and conduction in SA node.
-Increases contractility.
-Increase O2 demand by heart.
-Mimics the action of SNS on beta-1 and beta-2 receptors.
What are the therapeutic uses of adrenaline? ---------CORRECT
ANSWER------------------Used in combination with local anaesthetics to
prevent vasodilation by drugs by lignocaine.
-increase CO and HR.
-anaphylaxis
What neurotransmitter does the pre-ganglionic fibre release? ---------
CORRECT ANSWER-----------------Acetylcholine
What receptor does acetylcholine act on in the ganglia? ---------
CORRECT ANSWER-----------------Nicotinic receptors
, What neurotransmitter do post-ganglionic SNS fibres release? ---------
CORRECT ANSWER-----------------Noradrenaline
What receptors can Noradrenaline act on in the SNS? ---------CORRECT
ANSWER-----------------Beta 1
Beta 2
Alpha 1
Alpha 2
What receptors can acetylcholine act on in the PaNS? ---------CORRECT
ANSWER-----------------Muscarinic receptors
What is the exception for the SNS releasing noradrenaline? ---------
CORRECT ANSWER-----------------The sweat glands are the exception.
here the SNS releases Ach to act on muscarinic receptors.
The other exception is the adrenal gland, the SNS releases Ach to act on
nicotinic receptors.
DIFFERENT VERSIONS) | CARDIOVASCULAR
SYSTEM PHARMACOLOGY EXAM | ALL QUESTIONS
AND CORRECT ANSWERS | UPDATED VERSIONS
CVS Pharmacology Exam (First Version)
What is the MOA of alpha 1 agonists? ---------CORRECT ANSWER-----------
-------Increase alpha 1 activity. alpha 1 agonist, increase BP, -direct
topical doses causes vasoconstriction through direct alpha 1 effects in
nose.
-Mimics the effect of NA and Adrenaline on alpha -1 in vascular smooth
muscle.
What are the therapeutic uses of alpha 1 agonists? ---------CORRECT
ANSWER------------------Used as local decongestants in the nose and
conjunctivitis. Allergy rhinitis. Can also be taken systemically.
-treat allergies
-treat common colds
,What are the side effects of phenylephrine? ---------CORRECT ANSWER--
---------------rebound nasal congestion.
especially with topical version.
What are the contraindications of alpha 1 agonists? ---------CORRECT
ANSWER-----------------Contraindicated in uncontrolled hypertension.
Give examples of a alpha 1 agonists. ---------CORRECT ANSWER------------
-----Phenylephrine (topical and oral)
Ephedrine.
adrenalin.
What is the MOA of phenylephrine? ---------CORRECT ANSWER-------------
----direct alpha 1 agonist.
What is the MOA of ephedrine? ---------CORRECT ANSWER-----------------
causes release of both NA & A.
,What is the MOA of adrenaline? ---------CORRECT ANSWER-----------------
it is a direct alpha 1, beta 1 and beta 2 agonist.
-Increase conduction through AV node and conduction in SA node.
-Increases contractility.
-Increase O2 demand by heart.
-Mimics the action of SNS on beta-1 and beta-2 receptors.
What are the therapeutic uses of adrenaline? ---------CORRECT
ANSWER------------------Used in combination with local anaesthetics to
prevent vasodilation by drugs by lignocaine.
-increase CO and HR.
-anaphylaxis
What neurotransmitter does the pre-ganglionic fibre release? ---------
CORRECT ANSWER-----------------Acetylcholine
What receptor does acetylcholine act on in the ganglia? ---------
CORRECT ANSWER-----------------Nicotinic receptors
, What neurotransmitter do post-ganglionic SNS fibres release? ---------
CORRECT ANSWER-----------------Noradrenaline
What receptors can Noradrenaline act on in the SNS? ---------CORRECT
ANSWER-----------------Beta 1
Beta 2
Alpha 1
Alpha 2
What receptors can acetylcholine act on in the PaNS? ---------CORRECT
ANSWER-----------------Muscarinic receptors
What is the exception for the SNS releasing noradrenaline? ---------
CORRECT ANSWER-----------------The sweat glands are the exception.
here the SNS releases Ach to act on muscarinic receptors.
The other exception is the adrenal gland, the SNS releases Ach to act on
nicotinic receptors.
