Endocrine Pharmacology 4/6
1. hypothyroidism drugs: levothyroxine
liothyronine
liotrix
amour
2. hyperthyroidism drugs: synthetic anti thyroid drugs
beta blockers
3. thyroid cancer drugs: thyrotropin recominant human TSH
4. levothyroxine: similar in structure to T4
5. liothyronine: similar to T3, cost ineffective and has a short half lfie
6. Liotrix: T4:T3 4:1
7. dessicated thyroid (armour): desiccaated porcine or bovine thyroid glands
short shelf life
1/5
, 8. less common side effects of levothyroxine and liothyronine: angina
anxiety
choking sensaiton
weight loss
menstrual disease
abdominal cramps
hypersenitivity
9. what is levothyroxine and liothyronine detrimental in the treatment of: obesity
abnormal vaginal bleeding
depression
10. what is there a risk of with T3: cardiotoxicity
11. thioamides: prevent hormone synthesis by inhibiting thyroid peroxidase: PTU and MMI
12. half life of PTU and MMI: PTU is 1.5 hrs, MMI is 6 hours
13. Iodide (SSKI or Lugols solution): inhibit organification and hormone release
14. goal of SSKI or lugols: decrease the size and vascularity of hyperplastic gland
2/5
1. hypothyroidism drugs: levothyroxine
liothyronine
liotrix
amour
2. hyperthyroidism drugs: synthetic anti thyroid drugs
beta blockers
3. thyroid cancer drugs: thyrotropin recominant human TSH
4. levothyroxine: similar in structure to T4
5. liothyronine: similar to T3, cost ineffective and has a short half lfie
6. Liotrix: T4:T3 4:1
7. dessicated thyroid (armour): desiccaated porcine or bovine thyroid glands
short shelf life
1/5
, 8. less common side effects of levothyroxine and liothyronine: angina
anxiety
choking sensaiton
weight loss
menstrual disease
abdominal cramps
hypersenitivity
9. what is levothyroxine and liothyronine detrimental in the treatment of: obesity
abnormal vaginal bleeding
depression
10. what is there a risk of with T3: cardiotoxicity
11. thioamides: prevent hormone synthesis by inhibiting thyroid peroxidase: PTU and MMI
12. half life of PTU and MMI: PTU is 1.5 hrs, MMI is 6 hours
13. Iodide (SSKI or Lugols solution): inhibit organification and hormone release
14. goal of SSKI or lugols: decrease the size and vascularity of hyperplastic gland
2/5