🧪 NURS 5334 ANTIFUNGALS MOCK QUIZ
& ANS - ADVANCED PHARMACOLOGY FOR
NP STUDENTS| NEWEST UPDATE 2025/2026 |
UNIVERSITY OF TEXAS
NB Test your knowledge & check correct answers & Rationales
after every ten Quizzes
Document Contains
55 Questions with Answers & Rationales
✅ Answer Key + Rationales (Q1–15) page 6
✅ Answer Key + Rationales (Q16–25) page 12
✅ Answer Key + Rationales (Q26–35) page 17
✅ Answer Key + Rationales (Q36–45) page 24
✅ Answer Key + Rationales (Q46–55) page 30
1. Which of the following antifungals works by inhibiting
ergosterol synthesis through blocking squalene epoxidase?
1
,A. Fluconazole
B. Terbinafine
C. Nystatin
D. Itraconazole
2. A 34-year-old male is prescribed oral terbinafine for
onychomycosis. Which of the following is the most
appropriate monitoring plan?
A. Check electrolytes monthly
B. Perform liver function tests and CBC every 6 weeks if
treatment exceeds
6 weeks
C. Monitor BUN and creatinine weekly
D. No monitoring is needed with oral terbinafine
3. Which topical antifungal agent is specifically formulated as
a nail lacquer for mild onychomycosis involving ≤4 nails?
A. Efinaconazole
B. Ciclopirox
C. Ketoconazole
D. Nystatin
4. Which of the following patients should NOT receive
itraconazole?
2
,A. A patient with toenail onychomycosis
B. A patient with oral thrush
C. A patient with a history of congestive heart failure (CHF)
D. A patient with tinea corporis
5. Which statement regarding fluconazole is TRUE?
A. It requires therapeutic drug monitoring for effectiveness
B. It is contraindicated in pregnancy
C. It treats dermatophyte infections better than onychomycosis
D. It causes renal toxicity in most patients
6. A patient on griseofulvin asks what foods to take it with.
Which is the correct response?
A. "Take it on an empty stomach for best absorption."
B. "Take it with grapefruit juice to enhance bioavailability."
C. "Take it with a high-fat meal to improve absorption."
D. "Avoid dairy when taking this medication."
7. What is the most common adverse effect associated with
oral terbinafine?
A. Nephrotoxicity
B. Gastrointestinal upset
C. Bone marrow suppression
D. Alopecia
3
, 8. Which antifungal is most appropriate for treating oral
thrush in a 3-month-old infant?
A. Fluconazole
B. Itraconazole
C. Nystatin oral suspension
D. Ketoconazole oral tablets
9. What is the primary mechanism of action for azole
antifungals?
A. Binding to fungal RNA
B. Inhibiting ergosterol by targeting squalene
C. Binding directly to ergosterol and creating membrane pores
D. Inhibiting fungal CYP450 to block ergosterol synthesis
10. A patient is being treated with oral griseofulvin for tinea
capitis. Which lab monitoring is appropriate?
A. Liver enzymes, renal function, and CBC every 6–8 weeks
B. None needed for short-term use
C. Potassium and magnesium weekly
D. INR and PTT every 2 weeks
11. Which antifungal interacts with warfarin by reducing its
anticoagulant effect and requires INR monitoring?
4
& ANS - ADVANCED PHARMACOLOGY FOR
NP STUDENTS| NEWEST UPDATE 2025/2026 |
UNIVERSITY OF TEXAS
NB Test your knowledge & check correct answers & Rationales
after every ten Quizzes
Document Contains
55 Questions with Answers & Rationales
✅ Answer Key + Rationales (Q1–15) page 6
✅ Answer Key + Rationales (Q16–25) page 12
✅ Answer Key + Rationales (Q26–35) page 17
✅ Answer Key + Rationales (Q36–45) page 24
✅ Answer Key + Rationales (Q46–55) page 30
1. Which of the following antifungals works by inhibiting
ergosterol synthesis through blocking squalene epoxidase?
1
,A. Fluconazole
B. Terbinafine
C. Nystatin
D. Itraconazole
2. A 34-year-old male is prescribed oral terbinafine for
onychomycosis. Which of the following is the most
appropriate monitoring plan?
A. Check electrolytes monthly
B. Perform liver function tests and CBC every 6 weeks if
treatment exceeds
6 weeks
C. Monitor BUN and creatinine weekly
D. No monitoring is needed with oral terbinafine
3. Which topical antifungal agent is specifically formulated as
a nail lacquer for mild onychomycosis involving ≤4 nails?
A. Efinaconazole
B. Ciclopirox
C. Ketoconazole
D. Nystatin
4. Which of the following patients should NOT receive
itraconazole?
2
,A. A patient with toenail onychomycosis
B. A patient with oral thrush
C. A patient with a history of congestive heart failure (CHF)
D. A patient with tinea corporis
5. Which statement regarding fluconazole is TRUE?
A. It requires therapeutic drug monitoring for effectiveness
B. It is contraindicated in pregnancy
C. It treats dermatophyte infections better than onychomycosis
D. It causes renal toxicity in most patients
6. A patient on griseofulvin asks what foods to take it with.
Which is the correct response?
A. "Take it on an empty stomach for best absorption."
B. "Take it with grapefruit juice to enhance bioavailability."
C. "Take it with a high-fat meal to improve absorption."
D. "Avoid dairy when taking this medication."
7. What is the most common adverse effect associated with
oral terbinafine?
A. Nephrotoxicity
B. Gastrointestinal upset
C. Bone marrow suppression
D. Alopecia
3
, 8. Which antifungal is most appropriate for treating oral
thrush in a 3-month-old infant?
A. Fluconazole
B. Itraconazole
C. Nystatin oral suspension
D. Ketoconazole oral tablets
9. What is the primary mechanism of action for azole
antifungals?
A. Binding to fungal RNA
B. Inhibiting ergosterol by targeting squalene
C. Binding directly to ergosterol and creating membrane pores
D. Inhibiting fungal CYP450 to block ergosterol synthesis
10. A patient is being treated with oral griseofulvin for tinea
capitis. Which lab monitoring is appropriate?
A. Liver enzymes, renal function, and CBC every 6–8 weeks
B. None needed for short-term use
C. Potassium and magnesium weekly
D. INR and PTT every 2 weeks
11. Which antifungal interacts with warfarin by reducing its
anticoagulant effect and requires INR monitoring?
4
