PHARMACOLOGY EXAM 1 -
MULTIPLE CHOICE QUESTIONS
WITH CORRECT ANSWERS
2025/2026
1. The drug administration route demonstrating the slowest onset of
action is
a. inhalation
b. transdermal
c. intramuscular
d. sublingual
e. intravenous - correct answerB
2. Symptoms of Parkinsonism would be increased by
a. excess levels of acetylcholine
b. treatment with some antipsychotic drugs
c. decreased levels of dopamine
d. drug administration after a high-protein meal
e. all of these - correct answerI had ABC highlighted I think this
was a mistake please edit
3. The study of drug absorption, distribution, metabolism, and
excretion is known as
, a. pharmacotherapeutics
b. pharmacodynamics
c. pharmacokinetics
d. pharmacy
e. posology - correct answerC
4. 1.Barbiturate and benzodiazepine hypnotics both
a. increase NREM stage 2 sleep
b. increase REM sleep
c. increase NREM stage 4 sleep
d. cause REM rebound
e. all of these statements are true - correct answerA. increase
NREM stage 2 sleep
5. 1.The main pharmacologic effect of the SSRIs is
a. increase levels of norepinephrine
b. increase levels of serotonin
c. decrease levels of norepinephrine
d. decrease levels of serotonin
e. decrease levels of dopamine - correct answerB. increase
levels of serotonin
6. 10. Apomorphine is classified as
a. MAO-B inhibitor
b. dopamine receptor agonist
c. COMT inhibitor
d. anticholinergic drug
e. DOPA decarboxylase inhibitor - correct answerB. dopamine
receptor agonist
7. 10. The antianxiety effect of buspirone (BuSpar) is associated with
, a. stimulation of DA receptors
b. stimulation of serotonin receptors
c. blockage of serotonin receptors
d. blockade of dopamine receptors
e. blockage of GABA receptors - correct answerC. blockage of
serotonin receptors
8. 10. The time a drug continues to produce its effect is its
a. ED50
b. maximal response
c. ceiling effect
d. onset of action
e. duration of action - correct answerE
9. 11. Flumazenil (Romazicon) is used to reverse the depressant
effects of
a. clozapine
b. alprazolam (benzodiazepine)
c. haloperidol
d. chlorpromazine
e. thiothixene - correct answeralprazolam (benzodiazepine)
10. 12. What are the main areas at which benzodiazepines exert
their effects?
a. limbic system
b. cerebral cortex
c. reticular formation
d. spinal cord
e. all of these - correct answerE. all of these
11. 13. First-pass metabolism refers to the metabolism of drugs
in the
a. kidney
MULTIPLE CHOICE QUESTIONS
WITH CORRECT ANSWERS
2025/2026
1. The drug administration route demonstrating the slowest onset of
action is
a. inhalation
b. transdermal
c. intramuscular
d. sublingual
e. intravenous - correct answerB
2. Symptoms of Parkinsonism would be increased by
a. excess levels of acetylcholine
b. treatment with some antipsychotic drugs
c. decreased levels of dopamine
d. drug administration after a high-protein meal
e. all of these - correct answerI had ABC highlighted I think this
was a mistake please edit
3. The study of drug absorption, distribution, metabolism, and
excretion is known as
, a. pharmacotherapeutics
b. pharmacodynamics
c. pharmacokinetics
d. pharmacy
e. posology - correct answerC
4. 1.Barbiturate and benzodiazepine hypnotics both
a. increase NREM stage 2 sleep
b. increase REM sleep
c. increase NREM stage 4 sleep
d. cause REM rebound
e. all of these statements are true - correct answerA. increase
NREM stage 2 sleep
5. 1.The main pharmacologic effect of the SSRIs is
a. increase levels of norepinephrine
b. increase levels of serotonin
c. decrease levels of norepinephrine
d. decrease levels of serotonin
e. decrease levels of dopamine - correct answerB. increase
levels of serotonin
6. 10. Apomorphine is classified as
a. MAO-B inhibitor
b. dopamine receptor agonist
c. COMT inhibitor
d. anticholinergic drug
e. DOPA decarboxylase inhibitor - correct answerB. dopamine
receptor agonist
7. 10. The antianxiety effect of buspirone (BuSpar) is associated with
, a. stimulation of DA receptors
b. stimulation of serotonin receptors
c. blockage of serotonin receptors
d. blockade of dopamine receptors
e. blockage of GABA receptors - correct answerC. blockage of
serotonin receptors
8. 10. The time a drug continues to produce its effect is its
a. ED50
b. maximal response
c. ceiling effect
d. onset of action
e. duration of action - correct answerE
9. 11. Flumazenil (Romazicon) is used to reverse the depressant
effects of
a. clozapine
b. alprazolam (benzodiazepine)
c. haloperidol
d. chlorpromazine
e. thiothixene - correct answeralprazolam (benzodiazepine)
10. 12. What are the main areas at which benzodiazepines exert
their effects?
a. limbic system
b. cerebral cortex
c. reticular formation
d. spinal cord
e. all of these - correct answerE. all of these
11. 13. First-pass metabolism refers to the metabolism of drugs
in the
a. kidney
