NSG 4330 LIVER DISEASES PT 1 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES (VERIFIED
ANSWERS) ALREADY GRADED A+
What are the functional units of the liver? Ans✓✓✓hepatic lobules
What are the major functions of the liver? Ans✓✓✓CHO, protein and
fat metabolism, detoxification, bile production/excretion, glucose
storage (glycogen), immune function
What cells in the liver are related to immune function? Ans✓✓✓Kupfer
cells - macrophages involved in bacterial and toxin removal
What are risk factors for liver disease? Ans✓✓✓travel, alcohol use,
tylenol + other OTC drugs
Tylenol's antidote Ans✓✓✓acetylcysteine
What LFTs assess bile formation and excretion? Ans✓✓✓serum bili
(total, direct, indirect, urinary bili)
Protein metabolism liver tests Ans✓✓✓serum protein, alpha-fetoprotein,
blood ammonia
Hemostatic function liver tests Ans✓✓✓prothrombin
, What are the serum liver enzyme tests? Ans✓✓✓AST/ALT, ALP, GGT
AST/ALT tests increase when? Ans✓✓✓liver damage and inflammation
ALP increases when? Ans✓✓✓associated with bile duct injuries
GGT tests change with what? Ans✓✓✓hepatitis, ETOH related liver
disease, sensitive for biliary obstructions.
What lipid metabolism tests are done? Ans✓✓✓Serum Cholesterol
Jaundice Ans✓✓✓yellowish discoloration of body tissues. Abnormally
high bilirubin in blood. First appearance in sclera. Symptoms, not
disease,
When will hyperbilirubinemia present as jaundice? Ans✓✓✓won't
appear outwardly until 2x normal upper limit of bili
Conjugated vs unconjugated bilirubin Ans✓✓✓unconjugated is non-
water soluble. Becomes conjugated in liver, then can be secreted into
bile and eliminated in intestine
DETAILED ANSWERS WITH RATIONALES (VERIFIED
ANSWERS) ALREADY GRADED A+
What are the functional units of the liver? Ans✓✓✓hepatic lobules
What are the major functions of the liver? Ans✓✓✓CHO, protein and
fat metabolism, detoxification, bile production/excretion, glucose
storage (glycogen), immune function
What cells in the liver are related to immune function? Ans✓✓✓Kupfer
cells - macrophages involved in bacterial and toxin removal
What are risk factors for liver disease? Ans✓✓✓travel, alcohol use,
tylenol + other OTC drugs
Tylenol's antidote Ans✓✓✓acetylcysteine
What LFTs assess bile formation and excretion? Ans✓✓✓serum bili
(total, direct, indirect, urinary bili)
Protein metabolism liver tests Ans✓✓✓serum protein, alpha-fetoprotein,
blood ammonia
Hemostatic function liver tests Ans✓✓✓prothrombin
, What are the serum liver enzyme tests? Ans✓✓✓AST/ALT, ALP, GGT
AST/ALT tests increase when? Ans✓✓✓liver damage and inflammation
ALP increases when? Ans✓✓✓associated with bile duct injuries
GGT tests change with what? Ans✓✓✓hepatitis, ETOH related liver
disease, sensitive for biliary obstructions.
What lipid metabolism tests are done? Ans✓✓✓Serum Cholesterol
Jaundice Ans✓✓✓yellowish discoloration of body tissues. Abnormally
high bilirubin in blood. First appearance in sclera. Symptoms, not
disease,
When will hyperbilirubinemia present as jaundice? Ans✓✓✓won't
appear outwardly until 2x normal upper limit of bili
Conjugated vs unconjugated bilirubin Ans✓✓✓unconjugated is non-
water soluble. Becomes conjugated in liver, then can be secreted into
bile and eliminated in intestine
