CTBS Exam Prep with Complete
Solutions
What is an automatic deferral for heart valve donation?
a. History of Cancer
b. Obesity
c. Cardiomyopathy
d. Idiopathic Disorders - ANSWER-c. Cardiomyopathy
AATB standards require that tissue banking maintain SOPs encompassing all of the
following except:
a. Donor suitability criteria and record management policies
b. FDA regulations that apply to tissue banking
c. Procedures for monitoring in-process controls
d. Procedures describing criteria for exceptional release of tissue - ANSWER-b. FDA
regulations that apply to tissue banking
During skin processing, what is the maximum amount of time that skin can be exposed
to temperatures above 10 degrees Celsius?
a. 2hrs
b. 1hr
c. 8hr
d. 4hr - ANSWER-a. 2 hours
At what temperature shall cardiovascular tissue be stored?
a. -50 degree celsius or colder
b. -1 degree celsius or colder
c. -25 degree celsius or colder
d. -100 degree celsius or colder - ANSWER-d. -100 degree Celsius or colder
What must be considered for pediatric heart donors that have been breastfed in the 12
months prior to donation?
a. Length of time donor was fed
b. Mother's blood must be used for serology testing
c. Analysis of mother's risk for transmissible disease
d. Analysis of mother's nutritional habits - ANSWER-c. Analysis of mother's risk for
transmissible disease
Pre-processing cultures are:
a. Used to detect pathogenic yeast, viruses, & bacteria
b. Required by AATB standards
,c. Reviewed by the medical director designee
d. Preformed immediately after tissue exposure to antibiotics - ANSWER-b. Required by
AATB standards
Which of these blood cells produced in the trabecular area of long bones is responsible
for fighting infection?
a. Red Blood Cells
b. White Blood Cells
c. Platelets
d. Macrophages - ANSWER-b. White Blood Cells
When recovering bone from the lower extremities, which bone should be removed last?
a. Tibia
b. Iliac Crest
c. Femur
d. Calcaneous - ANSWER-b. Iliac Crest
Which of the following organisms cultured from skin shall make skin not suitable for
transplantation?
a. Cornebacterium Sp.
b. Coagulase-Negative Staphylococcuss
c. Staphylococcuss Aureus
d. Streptococcuss Viridans - ANSWER-c. Staphylococcuss Aureus
What is the correct temperature for short-term storage frozen tissue?
a. -30 degree celsius or colder
b. -4 degree celsius or colder
c. -20 degree celsius or colder
d. -40 degree celsius or colder - ANSWER-c. -20 degree celsius or colder
A 54yo married female with adult children is a potential donor. Who must give consent
for donation?
a. Mother
b. Brother or Sister
c. Adult Son or Daughter
d. Husband - ANSWER-d. Husband
For in process controls, what percentage of grafts must be swabbed for testing?
a. 100%
b. 20%
c. 10%
d. 50% - ANSWER-a. 100%
What is the maximum amount of time that a donor can remain unrefrigerated prior to the
commencement or recovery?
a. 24hrs
,b. 12hrs
c. 15hrs
d. 8hrs - ANSWER-c. 15 hours
Which of the following is a cryoprotectant
a. Isotonic Saline
b. Glycerol
c. RPMI
d. Typticase Soy Broth - ANSWER-b. Glycerol
The upper time limit from retrieval to processing of heart valves is
a. There is no time limit as long as aseptic technique is maintained during the recovery
b. Total ischemic time must not exceed 48hrs
c. Cold ischemic time must not exceed 48hrs
d. Warm ischemic time must not exceed 48hrs - ANSWER-b. Total ischemic time must
not exceed 48hrs
All tissues not already transplanted, which are subject to recall, shall be located and
quarantined pending resolution of the recall (T/F)? - ANSWER-True
Which of the following is not a colloid solution?
a. Fresh Frozen Plasma
b. Ringers Lactate
c. Dextran
d. Albumin - ANSWER-b. Ringers Lactate
What is the most common STD in the US?
a. HIV
b. Syphilis
c. Genital Herpes
d. Gonorrhea - ANSWER-c. Genital Herpes
What is the most common bloodbourne pathogen in the US today?
a. HIV
b. Hepatitis B
c. Hepatitis A
d. Hepatitis C - ANSWER-b. Hepatitis B
What is the minimum classed environment needed for processing of cardiovascular
tissue?
a. Not Applicable
b. Class 10 or Cleaner
c. Class 500 or Cleaner
d. Class 100 or Cleaner - ANSWER-d. Class 100 or Cleaner
What tissue transplant is most closely associated with CJD?
, a. Iliac Crest
b. Femur
c. Dura Mater
d. Skin - ANSWER-d. Dura Mater
Serological testing on a potential donor reveals a positive HIV antibody screening test.
The screening test is positive on repeat testing, but the confirmatory test result is
negative. What happens to the tissue.
a. May not be used; discrepant results obtained
b. May be used; HIV antibody test is not a required test
c. May be used; confirmatory test is negative
d. May not be used; results of confirmatory test cannot override a screening test -
ANSWER-d. May not be used; results of confirmatory test cannot override a screening
test
Which of the following is not a cause for deferral?
a. A Positive PPD Test for TB
b. Untreated Syphilis
c. Systemic Mycosis
d. Evidence of Sepsis - ANSWER-a. A Positive PPD Test for TB
Which of the following transplants is most commonly associated with spread of prion
related disease?
a. Skin
b. Dura Mater
c. Bone
d. Blood Transfusion - ANSWER-b. Dura Mater
Which of the following is NOT capable of osteoinduction?
a. Demineralized Allograft
b. Demineralized Xenograft
c. Demineralized Allopast
d. Demineralized Autograft - ANSWER-c. Demineralized Allopast
How long should donor records be held? (not including Dura mater)
a. 20yrs Beyond Date of Final Disposition
b. 5yrs Beyond the Date of Final Disposition
c. Not a Requirement
d. 10yrs Beyond Date of Final Disposition - ANSWER-d. 10yrs Beyond Date of Final
Disposition
Name the first civilian regional tissue bank established in the US.
a. University of Miami
b. Florida State University
c. United States Navy
d. University of Florida - ANSWER-a. University of Miami
Solutions
What is an automatic deferral for heart valve donation?
a. History of Cancer
b. Obesity
c. Cardiomyopathy
d. Idiopathic Disorders - ANSWER-c. Cardiomyopathy
AATB standards require that tissue banking maintain SOPs encompassing all of the
following except:
a. Donor suitability criteria and record management policies
b. FDA regulations that apply to tissue banking
c. Procedures for monitoring in-process controls
d. Procedures describing criteria for exceptional release of tissue - ANSWER-b. FDA
regulations that apply to tissue banking
During skin processing, what is the maximum amount of time that skin can be exposed
to temperatures above 10 degrees Celsius?
a. 2hrs
b. 1hr
c. 8hr
d. 4hr - ANSWER-a. 2 hours
At what temperature shall cardiovascular tissue be stored?
a. -50 degree celsius or colder
b. -1 degree celsius or colder
c. -25 degree celsius or colder
d. -100 degree celsius or colder - ANSWER-d. -100 degree Celsius or colder
What must be considered for pediatric heart donors that have been breastfed in the 12
months prior to donation?
a. Length of time donor was fed
b. Mother's blood must be used for serology testing
c. Analysis of mother's risk for transmissible disease
d. Analysis of mother's nutritional habits - ANSWER-c. Analysis of mother's risk for
transmissible disease
Pre-processing cultures are:
a. Used to detect pathogenic yeast, viruses, & bacteria
b. Required by AATB standards
,c. Reviewed by the medical director designee
d. Preformed immediately after tissue exposure to antibiotics - ANSWER-b. Required by
AATB standards
Which of these blood cells produced in the trabecular area of long bones is responsible
for fighting infection?
a. Red Blood Cells
b. White Blood Cells
c. Platelets
d. Macrophages - ANSWER-b. White Blood Cells
When recovering bone from the lower extremities, which bone should be removed last?
a. Tibia
b. Iliac Crest
c. Femur
d. Calcaneous - ANSWER-b. Iliac Crest
Which of the following organisms cultured from skin shall make skin not suitable for
transplantation?
a. Cornebacterium Sp.
b. Coagulase-Negative Staphylococcuss
c. Staphylococcuss Aureus
d. Streptococcuss Viridans - ANSWER-c. Staphylococcuss Aureus
What is the correct temperature for short-term storage frozen tissue?
a. -30 degree celsius or colder
b. -4 degree celsius or colder
c. -20 degree celsius or colder
d. -40 degree celsius or colder - ANSWER-c. -20 degree celsius or colder
A 54yo married female with adult children is a potential donor. Who must give consent
for donation?
a. Mother
b. Brother or Sister
c. Adult Son or Daughter
d. Husband - ANSWER-d. Husband
For in process controls, what percentage of grafts must be swabbed for testing?
a. 100%
b. 20%
c. 10%
d. 50% - ANSWER-a. 100%
What is the maximum amount of time that a donor can remain unrefrigerated prior to the
commencement or recovery?
a. 24hrs
,b. 12hrs
c. 15hrs
d. 8hrs - ANSWER-c. 15 hours
Which of the following is a cryoprotectant
a. Isotonic Saline
b. Glycerol
c. RPMI
d. Typticase Soy Broth - ANSWER-b. Glycerol
The upper time limit from retrieval to processing of heart valves is
a. There is no time limit as long as aseptic technique is maintained during the recovery
b. Total ischemic time must not exceed 48hrs
c. Cold ischemic time must not exceed 48hrs
d. Warm ischemic time must not exceed 48hrs - ANSWER-b. Total ischemic time must
not exceed 48hrs
All tissues not already transplanted, which are subject to recall, shall be located and
quarantined pending resolution of the recall (T/F)? - ANSWER-True
Which of the following is not a colloid solution?
a. Fresh Frozen Plasma
b. Ringers Lactate
c. Dextran
d. Albumin - ANSWER-b. Ringers Lactate
What is the most common STD in the US?
a. HIV
b. Syphilis
c. Genital Herpes
d. Gonorrhea - ANSWER-c. Genital Herpes
What is the most common bloodbourne pathogen in the US today?
a. HIV
b. Hepatitis B
c. Hepatitis A
d. Hepatitis C - ANSWER-b. Hepatitis B
What is the minimum classed environment needed for processing of cardiovascular
tissue?
a. Not Applicable
b. Class 10 or Cleaner
c. Class 500 or Cleaner
d. Class 100 or Cleaner - ANSWER-d. Class 100 or Cleaner
What tissue transplant is most closely associated with CJD?
, a. Iliac Crest
b. Femur
c. Dura Mater
d. Skin - ANSWER-d. Dura Mater
Serological testing on a potential donor reveals a positive HIV antibody screening test.
The screening test is positive on repeat testing, but the confirmatory test result is
negative. What happens to the tissue.
a. May not be used; discrepant results obtained
b. May be used; HIV antibody test is not a required test
c. May be used; confirmatory test is negative
d. May not be used; results of confirmatory test cannot override a screening test -
ANSWER-d. May not be used; results of confirmatory test cannot override a screening
test
Which of the following is not a cause for deferral?
a. A Positive PPD Test for TB
b. Untreated Syphilis
c. Systemic Mycosis
d. Evidence of Sepsis - ANSWER-a. A Positive PPD Test for TB
Which of the following transplants is most commonly associated with spread of prion
related disease?
a. Skin
b. Dura Mater
c. Bone
d. Blood Transfusion - ANSWER-b. Dura Mater
Which of the following is NOT capable of osteoinduction?
a. Demineralized Allograft
b. Demineralized Xenograft
c. Demineralized Allopast
d. Demineralized Autograft - ANSWER-c. Demineralized Allopast
How long should donor records be held? (not including Dura mater)
a. 20yrs Beyond Date of Final Disposition
b. 5yrs Beyond the Date of Final Disposition
c. Not a Requirement
d. 10yrs Beyond Date of Final Disposition - ANSWER-d. 10yrs Beyond Date of Final
Disposition
Name the first civilian regional tissue bank established in the US.
a. University of Miami
b. Florida State University
c. United States Navy
d. University of Florida - ANSWER-a. University of Miami
