NR 566 Final Exam 2026 Questions and
Answers
Primary Hypogonadism - Correct answer-results of testicular failure and is
characterized by low testosterone and elevated gonadotropins
Secondary Hypogonadism - Correct answer-result of hypothalamic-pituitary failure
and is characterized by low testosterone and low normal gonadotropins
Congenital hypogonadism - Correct answer-- result of insufficient amounts of
testosterone produce by the gonads during puberty.
-Delayed, arrested, or absent testicular growth and delayed development of
secondary sexual characteristics are hallmark signs
- Physical signs include a voice that does not deepen, no muscle mass increase, and
male sex organs that do not develop and mature
Symptoms of Hypogonadism in adults - Correct answer-Depression
Development of male breasts
Erectile dysfunction
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,Failure of facial and body hair to grow
Increase in body fat, loss of energy
Inhibited sexual desire
Loss of muscle mass
Onset of osteoporosis
Shrinking and softening of the testicles
Rational Drug Selection for ED - Correct answer-treatment includes
phosphodiesterase type 5 (PDE-5) inhibitors, or TRT
phosphodiesterase type 5 (PDE-5) inhibitors - Correct answer-sildenafil (Viagra),
vardenafil (Levitra), and tadalafil (Cialis)
Contraindications of PDE-5 inhibitors - Correct answer-- if taken concurrently with
nitrates (nitroglycerine) there is potential for fatal hypotension
- acute myocardial infarction, stroke, or arrhythmia in past 6 months
- HIV protease inhibitors
- riociguat or other guanylate cyclase stimulator
ADE of PDE 5 inhibitors - Correct answer-- fatal hypotension if taken with nitrates
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, - vision and hearing problems in rare cases
- MI
- Sickle Cell Anemia with vasoocclusive crisis
- optic neuropathy
-retinal hemorrhage
- priapism
Testosterone therapy effects - Correct answer-- Stimulates erythropoiesis
- Increased bone mass in eugonadal men
- Long-term benefit of TRT on bone mineral density is not known.
- May improve cognitive functioning
- Improves insulin sensitivity
- No association between TRT and cardiac events
- Has variable effects on mood, energy, and sense of well-being
- Muscle mass and strength
- May reverse age-dependent body composition changes and associated morbidity
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Answers
Primary Hypogonadism - Correct answer-results of testicular failure and is
characterized by low testosterone and elevated gonadotropins
Secondary Hypogonadism - Correct answer-result of hypothalamic-pituitary failure
and is characterized by low testosterone and low normal gonadotropins
Congenital hypogonadism - Correct answer-- result of insufficient amounts of
testosterone produce by the gonads during puberty.
-Delayed, arrested, or absent testicular growth and delayed development of
secondary sexual characteristics are hallmark signs
- Physical signs include a voice that does not deepen, no muscle mass increase, and
male sex organs that do not develop and mature
Symptoms of Hypogonadism in adults - Correct answer-Depression
Development of male breasts
Erectile dysfunction
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,Failure of facial and body hair to grow
Increase in body fat, loss of energy
Inhibited sexual desire
Loss of muscle mass
Onset of osteoporosis
Shrinking and softening of the testicles
Rational Drug Selection for ED - Correct answer-treatment includes
phosphodiesterase type 5 (PDE-5) inhibitors, or TRT
phosphodiesterase type 5 (PDE-5) inhibitors - Correct answer-sildenafil (Viagra),
vardenafil (Levitra), and tadalafil (Cialis)
Contraindications of PDE-5 inhibitors - Correct answer-- if taken concurrently with
nitrates (nitroglycerine) there is potential for fatal hypotension
- acute myocardial infarction, stroke, or arrhythmia in past 6 months
- HIV protease inhibitors
- riociguat or other guanylate cyclase stimulator
ADE of PDE 5 inhibitors - Correct answer-- fatal hypotension if taken with nitrates
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
, - vision and hearing problems in rare cases
- MI
- Sickle Cell Anemia with vasoocclusive crisis
- optic neuropathy
-retinal hemorrhage
- priapism
Testosterone therapy effects - Correct answer-- Stimulates erythropoiesis
- Increased bone mass in eugonadal men
- Long-term benefit of TRT on bone mineral density is not known.
- May improve cognitive functioning
- Improves insulin sensitivity
- No association between TRT and cardiac events
- Has variable effects on mood, energy, and sense of well-being
- Muscle mass and strength
- May reverse age-dependent body composition changes and associated morbidity
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
