10/26/25, 1:58 PM MMSC 433 exam 1 EXAM Questions with 100% Correct Answers | Verified | Updated (Actual Exam) 2025\2026 LATEST VERSIO…
MMSC 433 exam 1 EXAM Questions with 100%
Correct Answers | Verified | Updated (Actual
Exam) 2025\2026 LATEST VERSION!! EXAM
Questions with 100% Correct
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Terms in this set (82)
-ferric iron is taken in from diet
-ferric iron is reduced by duodenal cytochrome B to
become ferrous iron
iron absorption -ferrous iron is absorbed into enterocytes by DMT 1
-absorbed iron is stored as ferritin, or sent into portal
hepatic circulation and carried by transferrin to
developing RBCs
transferrin plasma carrier protein for ferrous iron
-hepcidin is released from hepatocytes
high iron level regulation -ferroportin is inactivated, leading to decreased iron
being transported into circulation
-hepcidin is down regulated by hepatocytes
low iron level regulation -ferroportin becomes activated and transports iron
out of the enterocytes and into circulation
red meat, legumes, dark leafy vegetables, whole
dietary iron sources
grains
the form of iron that is able to be utilized in the body
ferrous iron
for developing red cells
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,10/26/25, 1:58 PM MMSC 433 exam 1 EXAM Questions with 100% Correct Answers | Verified | Updated (Actual Exam) 2025\2026 LATEST VERSIO…
stain that is used to identify iron in tissues and bone
prussian blue stain
marrow
a chart that is used to compare
soluble transferrin receptors/
log ferritin to hemoglobin
concentration of reticulocytes
thomas plot
to identify the iron status of the
patient
-iron status is used to correlate
to certain diseases/ anemias
stage 1 iron deficiency -asymptomatic
(progressive loss of -RBCs develop normally
storage iron) -serum ferritin low
-subclinical symptoms
-hemoglobin in retics is decreased, hemogram
appears normal still
stage 2 iron deficiency
-iron deficiency erythropoiesis is occurring
(exhaustion of iron
-hepcidin decreased
storage pool)
-serum iron and ferritin decreased
-RDW, TIBC and sTRs increased
-prussian blue stain of BM is negative for iron
-patient exhibits fatigue, weakness, pallor, glossitis,
koilonychia and pica
stage 3 iron deficiency -H/H decreased
(frank anemia) -hypochromic/ microcytic anemia
-FEP, TIBC and sTR increased
-ferritin, hepcidin and serum iron decreased
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-iron deposits in the mitochondria of erythroblast
cells in the bone marrow interfere with biosynthesis of
heme
-caused by genetic inheritance of drugs/ bone
sideroblastic anemia marrow toxins (lead, antibiotics, chemotherapeutics)
-ringed sideroblasts are highly indicative of the
disease
-basophillic stippling is common in lead poisoning
-normocytic normochromic cells
-caused by inadequate intake, increased need or
malabsorption of iron, poor diet or chronic blood loss
-symptoms: fatigue, weakness, pallor, spooning of the
nails (koilonychia) and pica
iron deficiency anemia -H/H decreased
(IDA) -microcytic, hypochromic cells
-marked poikilocytosis (target cells, spherocytes, tear
drop cells and schistocytes)
-FEP, sTR and TIBC increased
-ferritin, hepcidin and serum iron decreased
-anemia occurring secondary to underlying condition
(chronic inflammatory disease, chronic infection or
malignancy) that causes release of cell products
-hepcidin, lactoferrin and inflammatory cytokines
cause decreased iron status and anemia
anemia of chronic
-low Hgb
inflammation
-low TIBC (hepcidin is increased due to acute phase
reaction)
-normocytic normochromic anemia
-serum iron decreased
-ferritin (acute phase reactant) and FEP increased
https://quizlet.com/1098556420/mmsc-433-exam-1-exam-questions-with-100-correct-answers-verified-updated-actual-exam-20252026-latest-version… 3/16
MMSC 433 exam 1 EXAM Questions with 100%
Correct Answers | Verified | Updated (Actual
Exam) 2025\2026 LATEST VERSION!! EXAM
Questions with 100% Correct
Save
Terms in this set (82)
-ferric iron is taken in from diet
-ferric iron is reduced by duodenal cytochrome B to
become ferrous iron
iron absorption -ferrous iron is absorbed into enterocytes by DMT 1
-absorbed iron is stored as ferritin, or sent into portal
hepatic circulation and carried by transferrin to
developing RBCs
transferrin plasma carrier protein for ferrous iron
-hepcidin is released from hepatocytes
high iron level regulation -ferroportin is inactivated, leading to decreased iron
being transported into circulation
-hepcidin is down regulated by hepatocytes
low iron level regulation -ferroportin becomes activated and transports iron
out of the enterocytes and into circulation
red meat, legumes, dark leafy vegetables, whole
dietary iron sources
grains
the form of iron that is able to be utilized in the body
ferrous iron
for developing red cells
https://quizlet.com/1098556420/mmsc-433-exam-1-exam-questions-with-100-correct-answers-verified-updated-actual-exam-20252026-latest-version… 1/16
,10/26/25, 1:58 PM MMSC 433 exam 1 EXAM Questions with 100% Correct Answers | Verified | Updated (Actual Exam) 2025\2026 LATEST VERSIO…
stain that is used to identify iron in tissues and bone
prussian blue stain
marrow
a chart that is used to compare
soluble transferrin receptors/
log ferritin to hemoglobin
concentration of reticulocytes
thomas plot
to identify the iron status of the
patient
-iron status is used to correlate
to certain diseases/ anemias
stage 1 iron deficiency -asymptomatic
(progressive loss of -RBCs develop normally
storage iron) -serum ferritin low
-subclinical symptoms
-hemoglobin in retics is decreased, hemogram
appears normal still
stage 2 iron deficiency
-iron deficiency erythropoiesis is occurring
(exhaustion of iron
-hepcidin decreased
storage pool)
-serum iron and ferritin decreased
-RDW, TIBC and sTRs increased
-prussian blue stain of BM is negative for iron
-patient exhibits fatigue, weakness, pallor, glossitis,
koilonychia and pica
stage 3 iron deficiency -H/H decreased
(frank anemia) -hypochromic/ microcytic anemia
-FEP, TIBC and sTR increased
-ferritin, hepcidin and serum iron decreased
https://quizlet.com/1098556420/mmsc-433-exam-1-exam-questions-with-100-correct-answers-verified-updated-actual-exam-20252026-latest-version… 2/16
, 10/26/25, 1:58 PM MMSC 433 exam 1 EXAM Questions with 100% Correct Answers | Verified | Updated (Actual Exam) 2025\2026 LATEST VERSIO…
-iron deposits in the mitochondria of erythroblast
cells in the bone marrow interfere with biosynthesis of
heme
-caused by genetic inheritance of drugs/ bone
sideroblastic anemia marrow toxins (lead, antibiotics, chemotherapeutics)
-ringed sideroblasts are highly indicative of the
disease
-basophillic stippling is common in lead poisoning
-normocytic normochromic cells
-caused by inadequate intake, increased need or
malabsorption of iron, poor diet or chronic blood loss
-symptoms: fatigue, weakness, pallor, spooning of the
nails (koilonychia) and pica
iron deficiency anemia -H/H decreased
(IDA) -microcytic, hypochromic cells
-marked poikilocytosis (target cells, spherocytes, tear
drop cells and schistocytes)
-FEP, sTR and TIBC increased
-ferritin, hepcidin and serum iron decreased
-anemia occurring secondary to underlying condition
(chronic inflammatory disease, chronic infection or
malignancy) that causes release of cell products
-hepcidin, lactoferrin and inflammatory cytokines
cause decreased iron status and anemia
anemia of chronic
-low Hgb
inflammation
-low TIBC (hepcidin is increased due to acute phase
reaction)
-normocytic normochromic anemia
-serum iron decreased
-ferritin (acute phase reactant) and FEP increased
https://quizlet.com/1098556420/mmsc-433-exam-1-exam-questions-with-100-correct-answers-verified-updated-actual-exam-20252026-latest-version… 3/16
