NR 566 Midterm NR566 MIDTERM EXAM
REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE Questions with Detailed
Verified Answers
Which non-amphetamines are FDA approved for weight loss that have lower abuse
risk? Ans: Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? Ans: -Promote
weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? Ans: 3
months or less
What drug schedule are Phentermine and Diethylpropion under? Ans: Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for? Ans: -baseline CMP (watch electrolytes and
creatinine)
-screen for depression
Phentermine adverse effects Ans: -increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? Ans: Increases satiety
What are some Phentermine/topiramate contraindications for use? Ans: not approved
in children and contraindicated with severe hepatic impairment
,How should we educate patient to take Phentermine/topiramate to avoid insomnia?
Ans: given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? Ans: hx drug abuse, glaucoma, pregnant, HTN,
hyperthyroidism
Phentermine/topiramate adverse effects Ans: insomnia, nervousness, anxiety,
depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. Ans: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat
by 30%. Ans: GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may
not be absorbed well when taking Orlistat. Ans: 2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. Ans: 12
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,Orlistat results in the least amount of weight loss of all. How much? Ans: 2-3% body
weight (7 lbs in year)
Orlistat adverse effects Ans: Fecal incontinence, oily rectal leakage, flatus, abdominal
cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? Ans: In those with malabsorption syndrome or
cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the
patient is on coumadin? Ans: Monitor Coumadin as Vitamin K deficiency may occur
and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered: Ans: overweight
Lorcaserin adverse effects Ans: headache, URI, back pain, hypoglycemia (in DM),
blood dyscrasias, cognitive impairment, psychiatric disorders, priapism, pulmonary
hypertension, and valvular heart disease
Lorcaserin MOA Ans: Reduces waist circumference, fasting glucose, insulin, total
cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated? Ans: CrCl <30
-Not approved in children
Lorcaserin drug interactions Ans: -MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and
triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning Ans: increased risk for suicidal ideation
and suicide attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. Ans: -
two
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, -MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
Ans: opioids
Naltrexone and Bupropion contraindications Ans: HTN, seizure disorders, eating
disorders, alcohol or drug withdrawal
Liraglutide MOA Ans: -promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
Ans: 10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes Ans:
hypoglycemia
Baseline labs for Liraglutide Ans: lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning Ans: associated with a risk for thyroid C-cell tumors
based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN
2) or personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more Ans:
150
What BMI is bariatric surgery considered? Ans: 35 or more
© Get it right 2025 Getaway - Stuvia US All rights reserved
REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE Questions with Detailed
Verified Answers
Which non-amphetamines are FDA approved for weight loss that have lower abuse
risk? Ans: Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? Ans: -Promote
weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? Ans: 3
months or less
What drug schedule are Phentermine and Diethylpropion under? Ans: Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for? Ans: -baseline CMP (watch electrolytes and
creatinine)
-screen for depression
Phentermine adverse effects Ans: -increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? Ans: Increases satiety
What are some Phentermine/topiramate contraindications for use? Ans: not approved
in children and contraindicated with severe hepatic impairment
,How should we educate patient to take Phentermine/topiramate to avoid insomnia?
Ans: given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? Ans: hx drug abuse, glaucoma, pregnant, HTN,
hyperthyroidism
Phentermine/topiramate adverse effects Ans: insomnia, nervousness, anxiety,
depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. Ans: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat
by 30%. Ans: GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may
not be absorbed well when taking Orlistat. Ans: 2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. Ans: 12
© Get it right 2025 Getaway - Stuvia US All rights reserved
,Orlistat results in the least amount of weight loss of all. How much? Ans: 2-3% body
weight (7 lbs in year)
Orlistat adverse effects Ans: Fecal incontinence, oily rectal leakage, flatus, abdominal
cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? Ans: In those with malabsorption syndrome or
cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the
patient is on coumadin? Ans: Monitor Coumadin as Vitamin K deficiency may occur
and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered: Ans: overweight
Lorcaserin adverse effects Ans: headache, URI, back pain, hypoglycemia (in DM),
blood dyscrasias, cognitive impairment, psychiatric disorders, priapism, pulmonary
hypertension, and valvular heart disease
Lorcaserin MOA Ans: Reduces waist circumference, fasting glucose, insulin, total
cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated? Ans: CrCl <30
-Not approved in children
Lorcaserin drug interactions Ans: -MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and
triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning Ans: increased risk for suicidal ideation
and suicide attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. Ans: -
two
© Get it right 2025 Getaway - Stuvia US All rights reserved
, -MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
Ans: opioids
Naltrexone and Bupropion contraindications Ans: HTN, seizure disorders, eating
disorders, alcohol or drug withdrawal
Liraglutide MOA Ans: -promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
Ans: 10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes Ans:
hypoglycemia
Baseline labs for Liraglutide Ans: lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning Ans: associated with a risk for thyroid C-cell tumors
based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN
2) or personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more Ans:
150
What BMI is bariatric surgery considered? Ans: 35 or more
© Get it right 2025 Getaway - Stuvia US All rights reserved
