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A patient receiving lamotrigine therapy has started using oral contraceptives. What is essential for the
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nurse to teach the patient?
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"With oral contraceptive use, you may need more lamotrigine."- When given with oral contraceptives,
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lamotrigine [1] [2] may need an increased dose to be effective because the oralcontraceptives also
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compete for the CYP450 enzyme pathway.
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What is appropriate information for the nurse to give the patient who is taking an antiepileptic drug witha
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narrow therapeutic index?
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Make certain the drug is taken at the same time daily.
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What is the appropriate way for the nurse to prepare a dosage of a suspension medication for a pediatric
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patient?
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Draw it up in an oral syringe
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A patient is receiving carbamazepine to treat trigeminal neuralgia. What assessment indicates atherapeutic
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response to the medication?
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The patient states no facial pain.
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A nurse is caring for a patient who has been started on antiepileptic drug therapy for seizures. What
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information should be included in the teaching plan for the patient?
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Take the medication at the sametime each day.
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Which intervention will best maintain therapeutic levels of an antiepileptic drug?
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Establish a drugregimen based on the half-life of the medication.
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Which patient should the nurse assess first?
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The patient taking carbamazepine who is not oriented to place or time.. - Any patient who is not oriented
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has a potential risk to his safety. The patient who is notoriented and taking carbamazepine could be
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experiencing adverse effects of therapy. This is the patient the nurse should assess first.
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Which patient is most likely to have toxic effects of antiepileptic therapy?
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The patient with a carbamazepine level of 15 mcg/mL- The only value listed that is above therapeutic
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plasma levels is thecarbamazepine, which has a therapeutic range of 4 to 12 mcg/mL; this patient is
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most likely to have toxic effects of therapy.
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A patient is receiving phenobarbital. What information is essential to include in the discharge teachingplan?
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Select all that apply.
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"This medication may cause confusion.", "Good dental care is essential while on this medication."
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"Don't drive until you determine how the medication affects you."- The most common adverse effects are
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lethargy and cognitive changes as well as gingival hyperplasia. Confusion can be a result of this therapy.
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,bt Good dental care is essential because the medication can cause gingival hyperplasia. The patientshould
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bt evaluate how the drug affects him before driving. bt bt bt bt bt bt bt
The nurse is caring for a patient with a phenytoin level of 12 mcg/mL. What is the nurse's best action?
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Continue to monitor the patient on this medication. bt bt bt bt bt bt bt
The nurse instructs a patient receiving phenytoin to visit the dentist regularly and perform frequent oral
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hygiene. What side effect will these interventions assist in preventing?
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Gingival hyperplasia bt
What is the goal of antiepileptic therapy?
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Maximally reducing seizure activity while minimizing sideeffects of medication therapy.
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The patient was started on an antiepileptic medication 6 weeks ago. The nurse notes that the patient'sblood
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level of the medication is very low after 6 weeks of therapy. How will the nurse interpret this result?
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The patient may not be taking the medication as ordered.
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The nurse is teaching a patient about therapy for a newly diagnosed seizure disorder. What statementshould
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the nurse include?"
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Your medication is chosen based on your type of seizure."
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What is the reason for many potential drug interactions with antiepileptic drug therapy?
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Altered CYP450 enzyme metabolism bt bt bt
What is important to teach the patient taking valproic acid for seizure management?
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Do not take the medication with milk or carbonated beverages. - Oral forms of valproic acid are not to be
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given with milk,because this may cause the drug to dissolve early and irritate the mucosa. Carbonated
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beverages must also be avoided during the time of drug administration.
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The health care provider has ordered once-daily phenytoin for an 8-year-old child who has a seizure
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disorder. The parents state the child cannot swallow pills. What intervention would the nurse
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recommend to the health care provider?
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Ask for a suspension form of the medication to be prescribed.
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The nurse is administering intravenous diazepam. When will the nurse expect the onset of action tooccur?
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Immediately
What intervention is appropriate to include in discharge teaching for a patient prescribed phenytoin
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therapy?
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Perform good oral hygiene. bt bt bt
The nurse is assessing a patient who is receiving antiepileptic drug therapy with phenytoin. What
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assessment finding requires immediate action?
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Nystagmus - The patient who has nystagmus may be presenting with adverse effects to phenytoin therapy
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and should be assessed for other signs of toxicity.
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, Which assessment is a priority for the patient starting on gabapentin therapy for a seizure disorder?
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Neurologic assessment - Gabapentin requires a thorough neurologic assessment, including baselineenergy
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levels, vision level, sensory and motor functioning, and any changes in speech.
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The nurse is caring for a patient who has been taking phenytoin for the past week and has developed arash.
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What is the first action the nurse should take?
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Assess the patient. bt bt
A patient with a seizure disorder is taking oral phenytoin. He is nothing by mouth (NPO) for electivesurgery.
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What is the appropriate nursing action?
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Call the health care provider to clarify medication orders.
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What assessment indicates the patient is having a therapeutic response to valproic acid?
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Absence of seizures bt bt
A patient has been taking valproic acid and is being switched to another medication due to elevated liver
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function tests. What nursing action is appropriate?
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Taper the valproic acid while starting the new medication.
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A patient is admitted who has reportedly stopped taking her antiepileptic medication. What is the
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appropriate nursing action?
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Monitor for rebound seizure activity. bt bt bt bt
What intervention is essential before a patient starts therapy with lamotrigine?
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Assessment of risk forStevens-Johnson syndrome bt bt bt b
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The nurse is administering intravenous phenytoin. When will the nurse expect the onset of the drug to
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occur?
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What information should the nurse provide to a patient who will self-administer an antiepileptic agentfor
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the first time at home?
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"Wait to see how you react to the medication before driving."
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The nurse is administering morning medications. Which administration technique is in error?1The
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bt nurse administers carbamazepine with grapefruit juice.
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