Which of the following is not considered an acute-phase protein?
A. C-reactive protein
B. Haptoglobin
C. Hemoglobin
D. Fibrinogen
C. Hemoglobin
All of the following are inflammation-associated cytokines except:
A. Interleukin-6.
B. TSH.
C. Interleukin-8.
D. TNF.
B. TSH.
Which of the following laboratory findings is most likely present in an individual with moderate-to-
severe COVID-19?
A. Lymphocytosis
B. Decreased prothrombin time
C. Decreased lactate dehydrogenase (LDH)
D. C-reactive protein (CRP) >5 mg/L
D. C-reactive protein (CRP) >5 mg/L
Of the following adults, who is most likely to have the highest ESR when healthy?
A. A 65-year-old woman
B. A 32-year-old man
C. A 45-year-old man
D. A 40-year-old woman
A. A 65-year-old woman
The erythrocyte sedimentation rate can be falsely decreased by the presence of:
A. Anisocytosis.
,B. Anemia
C. Leukopenia.
D. Macrocytosis.
A. Anisocytosis.
Which of the following is most likely to be present at the time of rheumatoid arthritis diagnosis?
A. Antinuclear antibodies
B. Neutropenia
C. Thrombocytopenia
D. Rheumatoid factor
D. Rheumatoid factor
Which of the following findings is associated with early or preclinical RA?
A. High RF, positive anti-CCP antibody
B. High RF, negative anti-CCP antibody
C. Low RF, positive anti-CCP antibody
D. Low RF, negative anti-CCP antibody
C. Low RF, positive anti-CCP antibody
A 45-year-old man with hypertension, type 2 diabetes mellitus and dyslipidemia presents with
suspected drug-induced lupus erythematosus (DILE). Of the following medications he is taking, which
is most likely to be implicated in DILE?
A. Trandolapril
B. Atenolol
C. Hydralazine
D. Clonidine
C. Hydralazine
In a person with drug-induced lupus erythematosus, which of the following is most likely to be
absent?
A. Recurrent fever
B. Muscle or joint pain
C. Diffuse maculopapular rash
D. Serositis
,C. Diffuse maculopapular rash
Which of the following best describes the clinical course of drug-induced lupus erythematosus?
A. Progressive nephritis even with the discontinuation of the offending medication
B. Resolution of symptoms and laboratory abnormalities upon discontinuation of the offending
medication
C. Resolution of symptoms with continued laboratory abnormalities upon discontinuation of the
offending medication
D. Continued symptoms with resolution of laboratory abnormalities upon discontinuation of the
offending medication
B. Resolution of symptoms and laboratory abnormalities upon discontinuation of the offending
medication
Anemia of chronic disease is present in approximately ______ of individuals when initially diagnosed
with RA.
A. 20%
B. 40%
C. 60%
D. 80%
D. 80%
In which of the following conditions is the ANA test most likely to be positive?
A. Sjögren’s syndrome
B. Graves’ disease
C. Dermatomyositis
D. Systemic lupus erythematosus
D. Systemic lupus erythematosus
Which of the following best indicates an evolving anemia?
A. Low MCV
B. Elevated MCV
C. Elevated RDW
D. Low MCHC
C. Elevated RDW
, Which of the following will most likely result in a normocytic, normochromic anemia?
A. Beta thalassemia minor
B. Presence of a chronic inflammatory condition
C. Long-term, excessive alcohol consumption
D. Lead toxicity
B. Presence of a chronic inflammatory condition
Which of the following is most consistent with a hemogram finding in iron deficiency anemia?
A, Low MCV, low MCHC, NL RDW
B. Low MCV, low MCHC, elevated RDW
C. Elevated MCV, normal MCHC, NL RDW
D. Normal MCV, normal MCHC, elevated RDW
B. Low MCV, low MCHC, elevated RDW
All of the following are types of macrocytic anemia except:
A. Vitamin B12 deficiency.
B. Pernicious anemia.
C. Folate deficiency anemia.
D. Anemia of chronic disease.
D. Anemia of chronic disease.
Concerning the evaluation of a red blood cell folate level, which of the following is true?
A. Potentially falsely lowered in person with rapidly developing folate deficiency
B. Influenced by dietary intake over the 24-hour period prior to the test
C. Remains stable throughout an individual RBC’s lifespan
D. Evaluates vitamin C deficiency in a chronically ill person
C. Remains stable throughout an individual RBC's lifespan
During a routine examination of a 24-year-old woman of Asian ancestry, the hemogram reveals a mild
microcytic anemia with elevated RBC and normal RDW. She does not report any symptoms and is
otherwise well. The most appropriate next-step test is:
A. Serum ferritin.
B. Fecal occult blood test.