GMS 6552 Study Guide with Exam Questions and Answers.

GMS 6552 Study Guide with Exam Questions and
Answers




G-protein coupled receptors - correct answers ✔️✔️Which type of receptor often utilizes second-
messenger systems?



-Kinase linked Receptors

-channel linked receptors

-nuclear receptors

-G-protein coupled receptors



nuclear receptors - correct answers ✔️✔️Assume you have receptor antagonists that are able to stop
receptor signaling immediately. for which type of receptor would take the longest to see the effects of
your drug at the cellular level?



-Kinase linked Receptors

-channel linked receptors

-nuclear receptors

-G-protein coupled receptors

, nuclear receptors - correct answers ✔️✔️For which type of receptor would having adequate membrane
permeability of an agonist be most critical?




-Kinase linked Receptors

-channel linked receptors

-nuclear receptors

-G-protein coupled receptors



N-terminus - correct answers ✔️✔️Is it more like for a GPCR agonist to bind near the N- or C- terminus
of the receptor?



N-terminus

C-terminus



GDP - correct answers ✔️✔️Is it more likely to find a GPCR bound to a G-protein that is also bound to
GTP or GDP?



-GTP

-GDP



STAT - correct answers ✔️✔️Which protein ultimately is translocated from the cytoplasm to the nucleus
as a result of JAK signaling?



-JAK

-GRB2

-SH2

-PI3K

-STAT