APHON Chemo Course exam questions |\ |\ |\ |\ |\
with answers |\
apoptosis - CORRECT ANSWERS ✔✔natural cell death
|\ |\ |\ |\ |\ |\
necrosis - CORRECT ANSWERS ✔✔cell death that results from an
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
insult, such as a lack of blood supply, physical trauma, or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
cytotoxic therapy that leads to rupture of the cell membrane and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
spilling of cell contents
|\ |\ |\
malignant cells - CORRECT ANSWERS ✔✔cells that do not have a
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
finite number of cell divisions as normal cells do; lost the ability
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
to undergo apoptosis; can keep replicating and dividing
|\ |\ |\ |\ |\ |\ |\ |\
indefinitely
aberrant cell division - CORRECT ANSWERS ✔✔the primary
|\ |\ |\ |\ |\ |\ |\ |\
characteristic of malignant cells |\ |\ |\
tumor suppression genes - CORRECT ANSWERS ✔✔these keep
|\ |\ |\ |\ |\ |\ |\ |\
normal cellular growth in check by regulating cell division, DNA
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
repair, and apoptosis; if damaged or absent, cells lack the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
appropriate growth-inhibiting signals and grow out of control
|\ |\ |\ |\ |\ |\ |\
nadir - CORRECT ANSWERS ✔✔the period of time after a course
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of chemotherapy in which the patients blood counts are lowest
|\ |\ |\ |\ |\ |\ |\ |\ |\
,physical barrier - CORRECT ANSWERS ✔✔the first layer of
|\ |\ |\ |\ |\ |\ |\ |\ |\
defense that provides protective immunity through anatomic
|\ |\ |\ |\ |\ |\ |\
barriers; ex. skin, mucous membranes
|\ |\ |\ |\
innate passive immunity - CORRECT ANSWERS ✔✔the second
|\ |\ |\ |\ |\ |\ |\ |\
layer of defense that provides rapid, nonspecific response to
|\ |\ |\ |\ |\ |\ |\ |\ |\
invading pathogens |\
adaptive acquired immunity - CORRECT ANSWERS ✔✔the third
|\ |\ |\ |\ |\ |\ |\ |\
layer of defense
|\ |\
tumor marker - CORRECT ANSWERS ✔✔a characteristic feature or
|\ |\ |\ |\ |\ |\ |\ |\
byproduct of a tumor cell that serves as a useful indication of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
tumor cell origin or tumor activity
|\ |\ |\ |\ |\
risk stratification - CORRECT ANSWERS ✔✔allows for tailoring
|\ |\ |\ |\ |\ |\ |\ |\
therapy after consideration of factors beyond those traditional
|\ |\ |\ |\ |\ |\ |\ |\
staging systems; this approach allows for early intensification of
|\ |\ |\ |\ |\ |\ |\ |\ |\
treatment
pharmacokinetics - CORRECT ANSWERS ✔✔the movement of a |\ |\ |\ |\ |\ |\ |\ |\
drug in the body and studies how the body affects the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
administered drug |\
pharmacogenetics - CORRECT ANSWERS ✔✔the study of how a |\ |\ |\ |\ |\ |\ |\ |\ |\
person's genetic makeup affects that person's response to drug
|\ |\ |\ |\ |\ |\ |\ |\ |\
therapy
, surgery - CORRECT ANSWERS ✔✔often used as a method for
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
treating cancer with the primary goal being to reduce the tumor
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
burden so that any remaining cancer cells can be more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
effectively destroyed by host immunologic factors, chemo, or |\ |\ |\ |\ |\ |\ |\ |\
immunotherapy
resection - CORRECT ANSWERS ✔✔surgical treatment of a tumor |\ |\ |\ |\ |\ |\ |\ |\ |\
by removing it
|\ |\
complete resection - CORRECT ANSWERS ✔✔surgical treatment |\ |\ |\ |\ |\ |\ |\
that involves the removal of all visible and microscopic evidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of the tumor
|\ |\
partial resection - CORRECT ANSWERS ✔✔surgical debulking that
|\ |\ |\ |\ |\ |\ |\ |\
involves resecting a portion of the tumor because the entire
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
mass cannot be completely or safely removed
|\ |\ |\ |\ |\ |\
chemotherapy - CORRECT ANSWERS ✔✔drug therapy aimed at |\ |\ |\ |\ |\ |\ |\ |\
reducing visible tumor volume by cytotoxic effects and |\ |\ |\ |\ |\ |\ |\ |\
preventing tumor cell division and spread; agents are designed to |\ |\ |\ |\ |\ |\ |\ |\ |\
kill malignant cells during different phases of the cell cycle
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
radiation therapy - CORRECT ANSWERS ✔✔the goal of treatment |\ |\ |\ |\ |\ |\ |\ |\ |\
is to target the tumor for destruction while sparing the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
surrounding tissues |\
autologous transplant - CORRECT ANSWERS ✔✔the patient is |\ |\ |\ |\ |\ |\ |\ |\
both the donor and the recipient, often given as a "rescue" after
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
with answers |\
apoptosis - CORRECT ANSWERS ✔✔natural cell death
|\ |\ |\ |\ |\ |\
necrosis - CORRECT ANSWERS ✔✔cell death that results from an
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
insult, such as a lack of blood supply, physical trauma, or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
cytotoxic therapy that leads to rupture of the cell membrane and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
spilling of cell contents
|\ |\ |\
malignant cells - CORRECT ANSWERS ✔✔cells that do not have a
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
finite number of cell divisions as normal cells do; lost the ability
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
to undergo apoptosis; can keep replicating and dividing
|\ |\ |\ |\ |\ |\ |\ |\
indefinitely
aberrant cell division - CORRECT ANSWERS ✔✔the primary
|\ |\ |\ |\ |\ |\ |\ |\
characteristic of malignant cells |\ |\ |\
tumor suppression genes - CORRECT ANSWERS ✔✔these keep
|\ |\ |\ |\ |\ |\ |\ |\
normal cellular growth in check by regulating cell division, DNA
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
repair, and apoptosis; if damaged or absent, cells lack the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
appropriate growth-inhibiting signals and grow out of control
|\ |\ |\ |\ |\ |\ |\
nadir - CORRECT ANSWERS ✔✔the period of time after a course
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of chemotherapy in which the patients blood counts are lowest
|\ |\ |\ |\ |\ |\ |\ |\ |\
,physical barrier - CORRECT ANSWERS ✔✔the first layer of
|\ |\ |\ |\ |\ |\ |\ |\ |\
defense that provides protective immunity through anatomic
|\ |\ |\ |\ |\ |\ |\
barriers; ex. skin, mucous membranes
|\ |\ |\ |\
innate passive immunity - CORRECT ANSWERS ✔✔the second
|\ |\ |\ |\ |\ |\ |\ |\
layer of defense that provides rapid, nonspecific response to
|\ |\ |\ |\ |\ |\ |\ |\ |\
invading pathogens |\
adaptive acquired immunity - CORRECT ANSWERS ✔✔the third
|\ |\ |\ |\ |\ |\ |\ |\
layer of defense
|\ |\
tumor marker - CORRECT ANSWERS ✔✔a characteristic feature or
|\ |\ |\ |\ |\ |\ |\ |\
byproduct of a tumor cell that serves as a useful indication of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
tumor cell origin or tumor activity
|\ |\ |\ |\ |\
risk stratification - CORRECT ANSWERS ✔✔allows for tailoring
|\ |\ |\ |\ |\ |\ |\ |\
therapy after consideration of factors beyond those traditional
|\ |\ |\ |\ |\ |\ |\ |\
staging systems; this approach allows for early intensification of
|\ |\ |\ |\ |\ |\ |\ |\ |\
treatment
pharmacokinetics - CORRECT ANSWERS ✔✔the movement of a |\ |\ |\ |\ |\ |\ |\ |\
drug in the body and studies how the body affects the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
administered drug |\
pharmacogenetics - CORRECT ANSWERS ✔✔the study of how a |\ |\ |\ |\ |\ |\ |\ |\ |\
person's genetic makeup affects that person's response to drug
|\ |\ |\ |\ |\ |\ |\ |\ |\
therapy
, surgery - CORRECT ANSWERS ✔✔often used as a method for
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
treating cancer with the primary goal being to reduce the tumor
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
burden so that any remaining cancer cells can be more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
effectively destroyed by host immunologic factors, chemo, or |\ |\ |\ |\ |\ |\ |\ |\
immunotherapy
resection - CORRECT ANSWERS ✔✔surgical treatment of a tumor |\ |\ |\ |\ |\ |\ |\ |\ |\
by removing it
|\ |\
complete resection - CORRECT ANSWERS ✔✔surgical treatment |\ |\ |\ |\ |\ |\ |\
that involves the removal of all visible and microscopic evidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of the tumor
|\ |\
partial resection - CORRECT ANSWERS ✔✔surgical debulking that
|\ |\ |\ |\ |\ |\ |\ |\
involves resecting a portion of the tumor because the entire
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
mass cannot be completely or safely removed
|\ |\ |\ |\ |\ |\
chemotherapy - CORRECT ANSWERS ✔✔drug therapy aimed at |\ |\ |\ |\ |\ |\ |\ |\
reducing visible tumor volume by cytotoxic effects and |\ |\ |\ |\ |\ |\ |\ |\
preventing tumor cell division and spread; agents are designed to |\ |\ |\ |\ |\ |\ |\ |\ |\
kill malignant cells during different phases of the cell cycle
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
radiation therapy - CORRECT ANSWERS ✔✔the goal of treatment |\ |\ |\ |\ |\ |\ |\ |\ |\
is to target the tumor for destruction while sparing the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
surrounding tissues |\
autologous transplant - CORRECT ANSWERS ✔✔the patient is |\ |\ |\ |\ |\ |\ |\ |\
both the donor and the recipient, often given as a "rescue" after
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\