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APHON Chemo Course exam questions with answers

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APHON Chemo Course exam questions with answers

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APHON Chemo Course exam questions |\ |\ |\ |\ |\




with answers |\




apoptosis - CORRECT ANSWERS ✔✔natural cell death
|\ |\ |\ |\ |\ |\




necrosis - CORRECT ANSWERS ✔✔cell death that results from an
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


insult, such as a lack of blood supply, physical trauma, or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


cytotoxic therapy that leads to rupture of the cell membrane and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


spilling of cell contents
|\ |\ |\




malignant cells - CORRECT ANSWERS ✔✔cells that do not have a
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


finite number of cell divisions as normal cells do; lost the ability
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


to undergo apoptosis; can keep replicating and dividing
|\ |\ |\ |\ |\ |\ |\ |\


indefinitely


aberrant cell division - CORRECT ANSWERS ✔✔the primary
|\ |\ |\ |\ |\ |\ |\ |\


characteristic of malignant cells |\ |\ |\




tumor suppression genes - CORRECT ANSWERS ✔✔these keep
|\ |\ |\ |\ |\ |\ |\ |\


normal cellular growth in check by regulating cell division, DNA
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


repair, and apoptosis; if damaged or absent, cells lack the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


appropriate growth-inhibiting signals and grow out of control
|\ |\ |\ |\ |\ |\ |\




nadir - CORRECT ANSWERS ✔✔the period of time after a course
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


of chemotherapy in which the patients blood counts are lowest
|\ |\ |\ |\ |\ |\ |\ |\ |\

,physical barrier - CORRECT ANSWERS ✔✔the first layer of
|\ |\ |\ |\ |\ |\ |\ |\ |\


defense that provides protective immunity through anatomic
|\ |\ |\ |\ |\ |\ |\


barriers; ex. skin, mucous membranes
|\ |\ |\ |\




innate passive immunity - CORRECT ANSWERS ✔✔the second
|\ |\ |\ |\ |\ |\ |\ |\


layer of defense that provides rapid, nonspecific response to
|\ |\ |\ |\ |\ |\ |\ |\ |\


invading pathogens |\




adaptive acquired immunity - CORRECT ANSWERS ✔✔the third
|\ |\ |\ |\ |\ |\ |\ |\


layer of defense
|\ |\




tumor marker - CORRECT ANSWERS ✔✔a characteristic feature or
|\ |\ |\ |\ |\ |\ |\ |\


byproduct of a tumor cell that serves as a useful indication of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


tumor cell origin or tumor activity
|\ |\ |\ |\ |\




risk stratification - CORRECT ANSWERS ✔✔allows for tailoring
|\ |\ |\ |\ |\ |\ |\ |\


therapy after consideration of factors beyond those traditional
|\ |\ |\ |\ |\ |\ |\ |\


staging systems; this approach allows for early intensification of
|\ |\ |\ |\ |\ |\ |\ |\ |\


treatment


pharmacokinetics - CORRECT ANSWERS ✔✔the movement of a |\ |\ |\ |\ |\ |\ |\ |\


drug in the body and studies how the body affects the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


administered drug |\




pharmacogenetics - CORRECT ANSWERS ✔✔the study of how a |\ |\ |\ |\ |\ |\ |\ |\ |\


person's genetic makeup affects that person's response to drug
|\ |\ |\ |\ |\ |\ |\ |\ |\


therapy

, surgery - CORRECT ANSWERS ✔✔often used as a method for
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


treating cancer with the primary goal being to reduce the tumor
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


burden so that any remaining cancer cells can be more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


effectively destroyed by host immunologic factors, chemo, or |\ |\ |\ |\ |\ |\ |\ |\


immunotherapy


resection - CORRECT ANSWERS ✔✔surgical treatment of a tumor |\ |\ |\ |\ |\ |\ |\ |\ |\


by removing it
|\ |\




complete resection - CORRECT ANSWERS ✔✔surgical treatment |\ |\ |\ |\ |\ |\ |\


that involves the removal of all visible and microscopic evidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


of the tumor
|\ |\




partial resection - CORRECT ANSWERS ✔✔surgical debulking that
|\ |\ |\ |\ |\ |\ |\ |\


involves resecting a portion of the tumor because the entire
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


mass cannot be completely or safely removed
|\ |\ |\ |\ |\ |\




chemotherapy - CORRECT ANSWERS ✔✔drug therapy aimed at |\ |\ |\ |\ |\ |\ |\ |\


reducing visible tumor volume by cytotoxic effects and |\ |\ |\ |\ |\ |\ |\ |\


preventing tumor cell division and spread; agents are designed to |\ |\ |\ |\ |\ |\ |\ |\ |\


kill malignant cells during different phases of the cell cycle
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




radiation therapy - CORRECT ANSWERS ✔✔the goal of treatment |\ |\ |\ |\ |\ |\ |\ |\ |\


is to target the tumor for destruction while sparing the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


surrounding tissues |\




autologous transplant - CORRECT ANSWERS ✔✔the patient is |\ |\ |\ |\ |\ |\ |\ |\


both the donor and the recipient, often given as a "rescue" after
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\

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