1|Page
Practice PMHNP-BC Exam Questions 2025-2026 Questions with
100% Correct Answers 2025 | 2026
This is an excellent, comprehensive set of review questions. To
help you study, I have compiled the second set of questions (the
multiple-choice format) into a definitive Question and Answer
list
PMHNP Certification Review Q&A List (Continued)
General Pharmacology & Treatment
Question Answer
Which of the following is the Antidepressants
first-line pharmacotherapy for (specifically SSRIs like
bulimia nervosa? Fluoxetine).
Which classification of
psychiatric medications SGA (Second Generation
requires routine lab work for Antipsychotics).
metabolic monitoring?
,2|Page
Question Answer
A patient who has been
hospitalized for acute
symptoms of schizophrenia
has been stabilized. He is being
Smoking (It induces the
discharged on Zyprexa 5 mg
CYP1A2 enzyme, rapidly
twice daily. Which of the
metabolizing
following behaviors, if
olanzapine/Zyprexa).
resumed, can impact the
efficacy of the psychotropic
medication and increase
symptoms?
Which statement is true Tobacco leads to
regarding the relationship decreased blood levels of
between tobacco use disorder the antipsychotic meds,
and reduced antipsychotic resulting in reduced
efficacy? efficacy.
How does the body remove
both serotonin and An active reuptake
norepinephrine from the process.
synaptic cleft?
, 3|Page
Question Answer
Target symptoms of
antidepressant treatment Impaired memory (and
include which of the concentration).
following?
Neurotransmitters & Physiology
Question Answer
What neurotransmitters are
Involvement of the
thought to be involved in the
dopamine system.
neurophysiology of psychosis?
_____'s function involves
normal functioning of thinking,
decision making, reward
Dopamine.
seeking behavior, fine muscle
action, and integrated
cognition.
_____'s function involves Norepi (Norepinephrine).
alertness orientation, fight or
Practice PMHNP-BC Exam Questions 2025-2026 Questions with
100% Correct Answers 2025 | 2026
This is an excellent, comprehensive set of review questions. To
help you study, I have compiled the second set of questions (the
multiple-choice format) into a definitive Question and Answer
list
PMHNP Certification Review Q&A List (Continued)
General Pharmacology & Treatment
Question Answer
Which of the following is the Antidepressants
first-line pharmacotherapy for (specifically SSRIs like
bulimia nervosa? Fluoxetine).
Which classification of
psychiatric medications SGA (Second Generation
requires routine lab work for Antipsychotics).
metabolic monitoring?
,2|Page
Question Answer
A patient who has been
hospitalized for acute
symptoms of schizophrenia
has been stabilized. He is being
Smoking (It induces the
discharged on Zyprexa 5 mg
CYP1A2 enzyme, rapidly
twice daily. Which of the
metabolizing
following behaviors, if
olanzapine/Zyprexa).
resumed, can impact the
efficacy of the psychotropic
medication and increase
symptoms?
Which statement is true Tobacco leads to
regarding the relationship decreased blood levels of
between tobacco use disorder the antipsychotic meds,
and reduced antipsychotic resulting in reduced
efficacy? efficacy.
How does the body remove
both serotonin and An active reuptake
norepinephrine from the process.
synaptic cleft?
, 3|Page
Question Answer
Target symptoms of
antidepressant treatment Impaired memory (and
include which of the concentration).
following?
Neurotransmitters & Physiology
Question Answer
What neurotransmitters are
Involvement of the
thought to be involved in the
dopamine system.
neurophysiology of psychosis?
_____'s function involves
normal functioning of thinking,
decision making, reward
Dopamine.
seeking behavior, fine muscle
action, and integrated
cognition.
_____'s function involves Norepi (Norepinephrine).
alertness orientation, fight or
