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Summary Short note of acute inflammation

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These notes are a clear and concise summary of Acute Inflammation from Robbins and Cotran Pathologic Basis of Disease (10th Edition). They are perfect for medical students, nursing students, and biology or pathology learners who want to quickly understand key mechanisms and definitions without going through long textbook paragraphs.

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Acute
inflammtion
Acute inflammtion is a protective response of vascular and
supporting elements of a tissue in response to infection and tissue
damage.



Cardinal features

Redness ( Rubor) Due to increased blood flow to the inflamed area.



Heat ( Calor) Due to increased flow of blood at body temperature into
Normally cooler inflamed area.


Pain ( dolor) Due to nerve damage or compression and release of chemicals
that stimulate nerve endings.




Swelling ( tumour) Due to leakage and accumulation of fluid.


Loss of function ( functio Due to combination of factors.
laesa)




Components
Circulating cells - neutrophils, eosinophils, basophils, lymphocytes and monocytes.
Platelets
Circulating proteins - clotting factors, complement components
Vascular endothelium
Connective tissue cells- macrophages, fibroblasts
Extracellular matrix - elastin, collagen

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  • acute inflammtion
  • robbins pathology

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