MMSC 433 Exam 3 Questions with |\ |\ |\ |\ |\ |\
correct answers |\
a "dry tap" bone marrow aspiration may be seen with what
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chronic myeloid proliferative disease?
|\ |\ |\
A: essential thrombocythemia
|\ |\
B: polycythemia vera
|\ |\
C: primary myelofibrosis
|\ |\
D: Chronic myeloid leukemia - CORRECT ANSWERS ✔✔Primary
|\ |\ |\ |\ |\ |\ |\ |\
myelofibrosis
what clinical feature is more often associated with essential
|\ |\ |\ |\ |\ |\ |\ |\ |\
thrombocythemia than with the other chronic myeloproliferative |\ |\ |\ |\ |\ |\ |\
disorders?
A: bleeding and thrombosis
|\ |\ |\
B: infections
|\
C: splenomegaly
|\
D: fatigue - CORRECT ANSWERS ✔✔bleeding and thromboses
|\ |\ |\ |\ |\ |\ |\
what is the most common chromosomal abnormality in
|\ |\ |\ |\ |\ |\ |\ |\
polycythemia vera (PV)? |\ |\
A: BCR-ABL
|\
,B: PML-RARA
|\
C: TET-2 |\
D: JAK2V617F - CORRECT ANSWERS ✔✔JAK2V617F
|\ |\ |\ |\ |\
which of the following is an expected finding in polycythemia
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
vera?
A: normal white cell count
|\ |\ |\ |\
B: anemia |\
C: increased RBC mass
|\ |\ |\
D: low leukocyte alkaline phosphatase - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔increased RBC mass |\ |\
a patient has a normal white cell count, a moderately high
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
platelet count, and mild anemia. The differential shows immature
|\ |\ |\ |\ |\ |\ |\ |\
granulocytes, nucleated red cells, and teardrop-shaped red cells.
|\ |\ |\ |\ |\ |\ |\ |\ |\
Which of the following is most likely?
|\ |\ |\ |\ |\ |\
A: chronic myelogenous leukoemia
|\ |\ |\
B: primary myelofibrosis
|\ |\
C: polycythemia vera
|\ |\
D: essential thrombocythemia - CORRECT ANSWERS ✔✔primary
|\ |\ |\ |\ |\ |\ |\
myelofibrosis
a patient has a platelet count of 1200*10⁹/L. Many platelets are
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
giant and have abnormal shapes. A mild anemia is present. The
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
, bone marrow has increased megakaryocytes in clusters; iron
|\ |\ |\ |\ |\ |\ |\ |\
stores are present. Which of the following is most likely?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A: chronic myelogenous leukemia
|\ |\ |\
B: polycythemia vera
|\ |\
C: thrombosis secondary to blood loss
|\ |\ |\ |\ |\
D: essential thrombocythemia - CORRECT ANSWERS ✔✔essential
|\ |\ |\ |\ |\ |\ |\
thrombocythemia
which one of the following chromosome abnormalities is
|\ |\ |\ |\ |\ |\ |\ |\
associated with CML? |\ |\
A: t(8;14)
|\
B: trisomy 18
|\ |\
C: t(15;17)
|\
D: t(9;22) - CORRECT ANSWERS ✔✔t(9;22)
|\ |\ |\ |\ |\
all of the following are minor criteria for overt PMF, except:
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A: WBC count < 10*10⁹/L
|\ |\ |\ |\
B: palpable splenomegaly
|\ |\
C: leukoerythroblastosis
|\
D: leukocytosis ≥ 11*10⁹/L - CORRECT ANSWERS ✔✔WBC count
|\ |\ |\ |\ |\ |\ |\ |\ |\
< 10*10⁹/L
|\
correct answers |\
a "dry tap" bone marrow aspiration may be seen with what
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chronic myeloid proliferative disease?
|\ |\ |\
A: essential thrombocythemia
|\ |\
B: polycythemia vera
|\ |\
C: primary myelofibrosis
|\ |\
D: Chronic myeloid leukemia - CORRECT ANSWERS ✔✔Primary
|\ |\ |\ |\ |\ |\ |\ |\
myelofibrosis
what clinical feature is more often associated with essential
|\ |\ |\ |\ |\ |\ |\ |\ |\
thrombocythemia than with the other chronic myeloproliferative |\ |\ |\ |\ |\ |\ |\
disorders?
A: bleeding and thrombosis
|\ |\ |\
B: infections
|\
C: splenomegaly
|\
D: fatigue - CORRECT ANSWERS ✔✔bleeding and thromboses
|\ |\ |\ |\ |\ |\ |\
what is the most common chromosomal abnormality in
|\ |\ |\ |\ |\ |\ |\ |\
polycythemia vera (PV)? |\ |\
A: BCR-ABL
|\
,B: PML-RARA
|\
C: TET-2 |\
D: JAK2V617F - CORRECT ANSWERS ✔✔JAK2V617F
|\ |\ |\ |\ |\
which of the following is an expected finding in polycythemia
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
vera?
A: normal white cell count
|\ |\ |\ |\
B: anemia |\
C: increased RBC mass
|\ |\ |\
D: low leukocyte alkaline phosphatase - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔increased RBC mass |\ |\
a patient has a normal white cell count, a moderately high
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
platelet count, and mild anemia. The differential shows immature
|\ |\ |\ |\ |\ |\ |\ |\
granulocytes, nucleated red cells, and teardrop-shaped red cells.
|\ |\ |\ |\ |\ |\ |\ |\ |\
Which of the following is most likely?
|\ |\ |\ |\ |\ |\
A: chronic myelogenous leukoemia
|\ |\ |\
B: primary myelofibrosis
|\ |\
C: polycythemia vera
|\ |\
D: essential thrombocythemia - CORRECT ANSWERS ✔✔primary
|\ |\ |\ |\ |\ |\ |\
myelofibrosis
a patient has a platelet count of 1200*10⁹/L. Many platelets are
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
giant and have abnormal shapes. A mild anemia is present. The
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
, bone marrow has increased megakaryocytes in clusters; iron
|\ |\ |\ |\ |\ |\ |\ |\
stores are present. Which of the following is most likely?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A: chronic myelogenous leukemia
|\ |\ |\
B: polycythemia vera
|\ |\
C: thrombosis secondary to blood loss
|\ |\ |\ |\ |\
D: essential thrombocythemia - CORRECT ANSWERS ✔✔essential
|\ |\ |\ |\ |\ |\ |\
thrombocythemia
which one of the following chromosome abnormalities is
|\ |\ |\ |\ |\ |\ |\ |\
associated with CML? |\ |\
A: t(8;14)
|\
B: trisomy 18
|\ |\
C: t(15;17)
|\
D: t(9;22) - CORRECT ANSWERS ✔✔t(9;22)
|\ |\ |\ |\ |\
all of the following are minor criteria for overt PMF, except:
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A: WBC count < 10*10⁹/L
|\ |\ |\ |\
B: palpable splenomegaly
|\ |\
C: leukoerythroblastosis
|\
D: leukocytosis ≥ 11*10⁹/L - CORRECT ANSWERS ✔✔WBC count
|\ |\ |\ |\ |\ |\ |\ |\ |\
< 10*10⁹/L
|\
