SOLUTIONS
1
What are the primary problems of depression? (2) Correct
Answer 1. mood
2. emotional disturbance
10
What happens with the depression and mania for people with
mixed bipolar disorder? Correct Answer they experience
depression and mania at the same time
100
For antidepressants, what are some other indications? (5)
Correct Answer 1. organic disorders
2. ANXIETY
3. sleep
4. eating disorders
5. ADHD
101
Name 3 organic disorders. Correct Answer 1. postpartum
(after giving birth)
2. grief
3. dementia (memory disorder)
102
Where did we get these treatments?
,How were antidepressants discovered? Correct Answer
discovered by accident
(discovered serendipitously)
103
Where did we get these treatments?
Antidepressants
Reserpine and ____________ Correct Answer hypertension
104
Where did we get these treatments?
Antidepressants
Tuberculosis (TB) and the _______ Correct Answer MAOIs
(monoamine oxidase inhibitors)
105 ??????
Where did we get these treatments?
Antidepressants
Imipramine was first use as an ______________. Correct
Answer antihistamine
(On slide it says:
discovery
mechanism of action)
106
,Serotonergic and Noradrenergic Actions of Antidepressants
What is the common neurobiological antidepressant
mechanism? Correct Answer controlling or blocking
serotonin
107
Discovery of Antidepressants
When was reserpine discovered? Correct Answer 1950s
108
Discovery of Antidepressants - Reserpine
What plant does reserpine come from?
Where was it used and to treat what? Correct Answer comes
from the plant Rauwolfia serpentine
used in India
to treat hypertension (stress) and "insanity"
109
Discovery of Antidepressants - Reserpine
In 1952, what were Western (like the US) drug companies
doing? Correct Answer investigating the properties of the
plant Rauwolfia serpentine and how it was used in India
11
, What does experiencing depression and mania at the same time
lead to while experiencing mixed bipolar disorder? Correct
Answer leads to unpredictable behavior, such as crying while
doing a favorite activity
110
Discovery of Antidepressants - Reserpine
Ciba isolated what in the plant? Correct Answer isolated the
active ingredient, Reserpine
111
Discovery of Antidepressants - Reserpine
What was noticed about use reserpine when it was first use for
hypertension? (2)
These results were similar to what other drug. Correct Answer
1. produced sedation
2. lowered temperature
Similar to chlorpromazine
112
What was chlorpromazine?
What did it treat? Correct Answer first antipsychotic drug
used to treat schizophrenia