D115 Master set-Advanced
Pathophysiology for the Advanced
Practice Nurse 2025 Expert Verified | Ace
the Test
Which type of genetic disease affects males more frequently than females?
- 🧠ANSWER ✔✔Sex-Linked recessive. Since males only have one X and
one Y, if the affected chromosome has the illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known
cause? - 🧠ANSWER ✔✔Intellectual disability and fetal miscarriage.
Chromosome abnormalities are the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - 🧠ANSWER
✔✔Chorionic villus sampling (CVS), amniocentesis, and preimplantation
genetic testing (PGT) are examples of prenatal diagnostic studies and are
,performed in vitro. CVS is a form of genetic testing that provides genetic
information found in utero and is usually performed between weeks 11 and
14 of pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the second
trimester, between weeks 15 and 20 of pregnancy. PGT is performed on
the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having
one chromosome with a normal complement of genes and one
chromosome with a missing gene? - 🧠ANSWER ✔✔Cri du chat syndrome
(translated as "cry of the cat") is caused by a DNA deletion. This term
describes the cry often heard from a baby affected by the syndrome. Cri du
chat syndrome can present as a microcephalic, low birth-weight baby with
a piercing cry.
How can an X-linked recessive disease skip generations? - 🧠ANSWER
✔✔The disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the mother may
provide an unaffected X to a daughter or son. Furthermore, a daughter may
,not show signs of the disease because she has the other X (the only X the
father can give to a female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among the
entire population to the disease rate in an unexposed population? -
🧠ANSWER ✔✔Relative risk is a ratio of probability, not an actual
occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? -
🧠ANSWER ✔✔Many factors from lifestyle to genetics affect multifactorial
diseases. Observation and evaluation of each case individually provides
the most thorough and accurate assessment.
What refers to the silenced gene of a gene pair. - 🧠ANSWER ✔✔The
imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired
inflammation and wound healing? - 🧠ANSWER ✔✔The underlying chronic
illness exists.
A generalized inflammatory response seen in chronic illness depletes the
body's reserves to fight against illness.
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, Which cells are the body's primary defense against parasite invasion? -
🧠ANSWER ✔✔Eosinophils are the body's primary defense against
parasites.
What Phagocytes bacteria? - 🧠ANSWER ✔✔Macrophages work by eating
or phagocytosing bacteria.
What is the first response to a foreign pathogen? - 🧠ANSWER ✔✔Helper T
cells
Which characteristic is the most important determinant of immunogenicity
when considering the antigen? - 🧠ANSWER ✔✔Immunogenicity is primarily
based on the ability to recognize something foreign.
How are erythrocytes destroyed when mismatched blood is administered,
causing an ABO incompatibility? - 🧠ANSWER ✔✔The complement
pathway is activated in response to blood incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? -
🧠ANSWER ✔✔An immediate (type I) hypersensitivity reaction causes
atopic dermatitis.
Pathophysiology for the Advanced
Practice Nurse 2025 Expert Verified | Ace
the Test
Which type of genetic disease affects males more frequently than females?
- 🧠ANSWER ✔✔Sex-Linked recessive. Since males only have one X and
one Y, if the affected chromosome has the illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known
cause? - 🧠ANSWER ✔✔Intellectual disability and fetal miscarriage.
Chromosome abnormalities are the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - 🧠ANSWER
✔✔Chorionic villus sampling (CVS), amniocentesis, and preimplantation
genetic testing (PGT) are examples of prenatal diagnostic studies and are
,performed in vitro. CVS is a form of genetic testing that provides genetic
information found in utero and is usually performed between weeks 11 and
14 of pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the second
trimester, between weeks 15 and 20 of pregnancy. PGT is performed on
the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having
one chromosome with a normal complement of genes and one
chromosome with a missing gene? - 🧠ANSWER ✔✔Cri du chat syndrome
(translated as "cry of the cat") is caused by a DNA deletion. This term
describes the cry often heard from a baby affected by the syndrome. Cri du
chat syndrome can present as a microcephalic, low birth-weight baby with
a piercing cry.
How can an X-linked recessive disease skip generations? - 🧠ANSWER
✔✔The disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the mother may
provide an unaffected X to a daughter or son. Furthermore, a daughter may
,not show signs of the disease because she has the other X (the only X the
father can give to a female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among the
entire population to the disease rate in an unexposed population? -
🧠ANSWER ✔✔Relative risk is a ratio of probability, not an actual
occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? -
🧠ANSWER ✔✔Many factors from lifestyle to genetics affect multifactorial
diseases. Observation and evaluation of each case individually provides
the most thorough and accurate assessment.
What refers to the silenced gene of a gene pair. - 🧠ANSWER ✔✔The
imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired
inflammation and wound healing? - 🧠ANSWER ✔✔The underlying chronic
illness exists.
A generalized inflammatory response seen in chronic illness depletes the
body's reserves to fight against illness.
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, Which cells are the body's primary defense against parasite invasion? -
🧠ANSWER ✔✔Eosinophils are the body's primary defense against
parasites.
What Phagocytes bacteria? - 🧠ANSWER ✔✔Macrophages work by eating
or phagocytosing bacteria.
What is the first response to a foreign pathogen? - 🧠ANSWER ✔✔Helper T
cells
Which characteristic is the most important determinant of immunogenicity
when considering the antigen? - 🧠ANSWER ✔✔Immunogenicity is primarily
based on the ability to recognize something foreign.
How are erythrocytes destroyed when mismatched blood is administered,
causing an ABO incompatibility? - 🧠ANSWER ✔✔The complement
pathway is activated in response to blood incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? -
🧠ANSWER ✔✔An immediate (type I) hypersensitivity reaction causes
atopic dermatitis.
