Toxicology Test quizzes with
answers graded A+
Toxicogenetics is involved with.... - ANS✅✅-Explaining individual repose differences to the same
toxicant
-Identifying polymorphisms in genes related to toxicant response
-The development of new therapies.
The most common route of accidental exposure to toxicants in toddlers is...? - ANS✅✅Ingestion
Gray baby syndrome is due in part to....? - ANS✅✅-The toxic response to chloramphenicol
-Immature kidneys
The purposely fatal intoxication of an individual is investigated by...? - ANS✅✅A forensic
toxicologist
A toxicant which comes into contact with an individual through the skin....? - ANS✅✅Can be
metabolized through the liver
The toxic effect of chronic exposure to benzene is....? Acute? - ANS✅✅Chronic: Leukemia
Acute: CNS Depression
The increased toxicity of normal young children to certain toxicants is due to...? - ANS✅✅-Blood-
brain barrier not fully developed
-Lack of metabolizing enzymes
The combination of carbon tetrachloride with ethanol on liver toxicity results in...? - ANS✅✅A
synergistic effect [More than additive (2+2=10)]
Two compounds which present and effect of 2+2=6 indicated that...? - ANS✅✅-Both are toxic
-Both have a synergistic effect
, When two substances act on the same physiological function with opposing effects, we have....? -
ANS✅✅Functional antagonism
The treatment of an overdose of anticoagulant Warfarin with phenobarbital is an example of...? -
ANS✅✅Dispositional antagonism
An example of a therapy involving receptor antagonism is...? - ANS✅✅The use of tamoxifen in
cancer
Tolerance...? - ANS✅✅1. Requires previous exposure to the chemical
2. Can result from decreased chemical reaching its target
3. Can result from reduced responsiveness of the tissue
4. Results from the induction of protective mechanisms
The dose-response relationship of a toxic effect for and individual is...? - ANS✅✅-The graded
response
-Is continuous when measured through a range of dose
Which of this is typical of the dose-response curve in Hormesis? - ANS✅✅At low doses its
protective
The therapeutic index is...? - ANS✅✅-The conc. at which a compound can be used safely
-The ratio between the toxic dose and effective dose TD50/ED50
-The higher the better
Two compounds which present an effect of 4 + (-4) = 0 indicates that...? - ANS✅✅-They antagonize
-One has the opposite effect
Which of the following is NOT correct for the undesired effects of therapeutic drugs are....? -
ANS✅✅They are never useful
Haptens are? - ANS✅✅Allergenic only when bound to protien
answers graded A+
Toxicogenetics is involved with.... - ANS✅✅-Explaining individual repose differences to the same
toxicant
-Identifying polymorphisms in genes related to toxicant response
-The development of new therapies.
The most common route of accidental exposure to toxicants in toddlers is...? - ANS✅✅Ingestion
Gray baby syndrome is due in part to....? - ANS✅✅-The toxic response to chloramphenicol
-Immature kidneys
The purposely fatal intoxication of an individual is investigated by...? - ANS✅✅A forensic
toxicologist
A toxicant which comes into contact with an individual through the skin....? - ANS✅✅Can be
metabolized through the liver
The toxic effect of chronic exposure to benzene is....? Acute? - ANS✅✅Chronic: Leukemia
Acute: CNS Depression
The increased toxicity of normal young children to certain toxicants is due to...? - ANS✅✅-Blood-
brain barrier not fully developed
-Lack of metabolizing enzymes
The combination of carbon tetrachloride with ethanol on liver toxicity results in...? - ANS✅✅A
synergistic effect [More than additive (2+2=10)]
Two compounds which present and effect of 2+2=6 indicated that...? - ANS✅✅-Both are toxic
-Both have a synergistic effect
, When two substances act on the same physiological function with opposing effects, we have....? -
ANS✅✅Functional antagonism
The treatment of an overdose of anticoagulant Warfarin with phenobarbital is an example of...? -
ANS✅✅Dispositional antagonism
An example of a therapy involving receptor antagonism is...? - ANS✅✅The use of tamoxifen in
cancer
Tolerance...? - ANS✅✅1. Requires previous exposure to the chemical
2. Can result from decreased chemical reaching its target
3. Can result from reduced responsiveness of the tissue
4. Results from the induction of protective mechanisms
The dose-response relationship of a toxic effect for and individual is...? - ANS✅✅-The graded
response
-Is continuous when measured through a range of dose
Which of this is typical of the dose-response curve in Hormesis? - ANS✅✅At low doses its
protective
The therapeutic index is...? - ANS✅✅-The conc. at which a compound can be used safely
-The ratio between the toxic dose and effective dose TD50/ED50
-The higher the better
Two compounds which present an effect of 4 + (-4) = 0 indicates that...? - ANS✅✅-They antagonize
-One has the opposite effect
Which of the following is NOT correct for the undesired effects of therapeutic drugs are....? -
ANS✅✅They are never useful
Haptens are? - ANS✅✅Allergenic only when bound to protien
