NAPLEX Exam Review - Pharmacy Foundations Part
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
What is the primary NT of the somatic nervous system and what receptors does it
bind? - CORRECT ANSWERS ACh
nicotinic (skeletal muscle)
parasympathetic nervous system NT/receptors/effects - CORRECT ANSWERS
ACh
muscarinic
SLUDD: salivation, lacrimation, urination, defecation, digestion
"rest and digest"
sympathetic nervous system NTs/receptors/effects - CORRECT ANSWERS
Epi/NE
alpha/beta (adrenergic)
↑ BP, HR, bronchodilation
muscarinic agonists (2) and antagonists (2) - CORRECT ANSWERS agonists:
pilocarpine, bethanechol
antagonists: atropine, oxybutynin
nicotinic agonist and antagonist - CORRECT ANSWERS agonist: nicotine
antagonist: rocuronium
α-1 agonists (2) and antagonists (3), actions - CORRECT ANSWERS peripheral
agonists: phenylephrine, DA (dose-dependent) → smooth muscle vasoconstriction
antagonists: doxazosin, carvedilol, phentolamine → vasodilation
α-2 agonists (2) and antagonists (2), actions - CORRECT ANSWERS brain/CNS
agonists: clonidine, brimonidine → decrease Epi/NE release
antagonists: ergot alkaloids, yohimbine
,NAPLEX Exam Review - Pharmacy Foundations Part
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
β-1 agonists (3) and antagonists (3) - CORRECT ANSWERS heart
agonists: dobutamine, isoproterenol, DA (dose-dependent)
antagonists: metoprolol, propranolol, carvedilol
β-2 agonists (3) and antagonists (2) - CORRECT ANSWERS lungs
agonists: albuterol, terbutaline, isoproterenol
antagonists: propranolol, carvedilol
DA agonists (2) and antagonists (2) - CORRECT ANSWERS renal, CV, CNS
agonists: levodopa, pramipexole
antagonists: FGAs/haloperidol, metoclopramide
5HT agonist (1) and antagonists (2) - CORRECT ANSWERS platelets, GI, CNS
agonists: triptans
antagonists: ondansetron, SGAs/quetiapine
AChEIs (3), action - CORRECT ANSWERS donepezil, rivastigmine, galantamine
block breakdown of ACh (Alzheimer's)
ACEI effects - CORRECT ANSWERS decrease vasoconstriction and aldosterone
release (HTN, HF, CKD)
COMT inhibitor, effect - CORRECT ANSWERS entacapone
block breakdown of levodopa (PD)
NSAID action, effect - CORRECT ANSWERS block COX from converting
arachidonic acid to prostaglandins (inflammation) and TXA2 (platelet aggregation)
, NAPLEX Exam Review - Pharmacy Foundations Part
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
MAOIs (7), action, effects - CORRECT ANSWERS phenelzine, tranylcypromine,
isocarboxazid, selegiline, rasagiline, methylene blue, linezolid
- block breakdown of catecholamines (DA, NE, Epi, 5HT)
- additive increase → HTN crisis
- increased 5HT → serotonin syndrome
PDE-5 inhibitors, effect - CORRECT ANSWERS -afil
block breakdown of cGMP for prolonged smooth muscle relaxation (ED)
warfarin action - CORRECT ANSWERS blocks vitamin K epoxide reductase → Vit
K not active → reduced clotting factors
xanthine oxidase inhibitor, efffect - CORRECT ANSWERS allopurinol
blocks breakdown of hypoxanthine/xanthine to uric acid (gout)
how to tell an ester vs amide anesthetic - CORRECT ANSWERS amide has "I"
before -caine
hydroxyl/alcohol (primary) - CORRECT ANSWERS neutral
ketone - CORRECT ANSWERS neutral
aldehyde - CORRECT ANSWERS neutral
amide - CORRECT ANSWERS neutral
nitrate - CORRECT ANSWERS neutral
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
What is the primary NT of the somatic nervous system and what receptors does it
bind? - CORRECT ANSWERS ACh
nicotinic (skeletal muscle)
parasympathetic nervous system NT/receptors/effects - CORRECT ANSWERS
ACh
muscarinic
SLUDD: salivation, lacrimation, urination, defecation, digestion
"rest and digest"
sympathetic nervous system NTs/receptors/effects - CORRECT ANSWERS
Epi/NE
alpha/beta (adrenergic)
↑ BP, HR, bronchodilation
muscarinic agonists (2) and antagonists (2) - CORRECT ANSWERS agonists:
pilocarpine, bethanechol
antagonists: atropine, oxybutynin
nicotinic agonist and antagonist - CORRECT ANSWERS agonist: nicotine
antagonist: rocuronium
α-1 agonists (2) and antagonists (3), actions - CORRECT ANSWERS peripheral
agonists: phenylephrine, DA (dose-dependent) → smooth muscle vasoconstriction
antagonists: doxazosin, carvedilol, phentolamine → vasodilation
α-2 agonists (2) and antagonists (2), actions - CORRECT ANSWERS brain/CNS
agonists: clonidine, brimonidine → decrease Epi/NE release
antagonists: ergot alkaloids, yohimbine
,NAPLEX Exam Review - Pharmacy Foundations Part
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
β-1 agonists (3) and antagonists (3) - CORRECT ANSWERS heart
agonists: dobutamine, isoproterenol, DA (dose-dependent)
antagonists: metoprolol, propranolol, carvedilol
β-2 agonists (3) and antagonists (2) - CORRECT ANSWERS lungs
agonists: albuterol, terbutaline, isoproterenol
antagonists: propranolol, carvedilol
DA agonists (2) and antagonists (2) - CORRECT ANSWERS renal, CV, CNS
agonists: levodopa, pramipexole
antagonists: FGAs/haloperidol, metoclopramide
5HT agonist (1) and antagonists (2) - CORRECT ANSWERS platelets, GI, CNS
agonists: triptans
antagonists: ondansetron, SGAs/quetiapine
AChEIs (3), action - CORRECT ANSWERS donepezil, rivastigmine, galantamine
block breakdown of ACh (Alzheimer's)
ACEI effects - CORRECT ANSWERS decrease vasoconstriction and aldosterone
release (HTN, HF, CKD)
COMT inhibitor, effect - CORRECT ANSWERS entacapone
block breakdown of levodopa (PD)
NSAID action, effect - CORRECT ANSWERS block COX from converting
arachidonic acid to prostaglandins (inflammation) and TXA2 (platelet aggregation)
, NAPLEX Exam Review - Pharmacy Foundations Part
1 (Ch 2-8) Test Exam With 202Questions and Answers
All Answers 100% Verified (Latest Update 2025/2026
RATED A+
MAOIs (7), action, effects - CORRECT ANSWERS phenelzine, tranylcypromine,
isocarboxazid, selegiline, rasagiline, methylene blue, linezolid
- block breakdown of catecholamines (DA, NE, Epi, 5HT)
- additive increase → HTN crisis
- increased 5HT → serotonin syndrome
PDE-5 inhibitors, effect - CORRECT ANSWERS -afil
block breakdown of cGMP for prolonged smooth muscle relaxation (ED)
warfarin action - CORRECT ANSWERS blocks vitamin K epoxide reductase → Vit
K not active → reduced clotting factors
xanthine oxidase inhibitor, efffect - CORRECT ANSWERS allopurinol
blocks breakdown of hypoxanthine/xanthine to uric acid (gout)
how to tell an ester vs amide anesthetic - CORRECT ANSWERS amide has "I"
before -caine
hydroxyl/alcohol (primary) - CORRECT ANSWERS neutral
ketone - CORRECT ANSWERS neutral
aldehyde - CORRECT ANSWERS neutral
amide - CORRECT ANSWERS neutral
nitrate - CORRECT ANSWERS neutral
