FHEA UPDATED ACTUAL Questions and CORRECT Answers
1. candidates for BMI > 40
weight loss BMI > 35 w/ related health conditions
surgery
2. Signs of Addi- hypoglycemia, Na+ and K+ imbalance, weight loss, hypotension, high ACTH levels
son's disease Diffuse hyperpigmentation, loss of axillary hair
3. MOA glipizide Stimulates insulin release from the pancreatic beta cells; reduces glucose output
from the liver; insulin sensitivity is increased at peripheral target sites
4. Sitagliptin ( Janu- Inhibits DPP-4 which reduces the destruction of incretins thereby increases levels
via) MOA of incretin hormones. This increases insulin and decreases blood sugar.
Note- even though it increases insulin- unlikely to cause hypoglycemia!
5. Insulin reducing can only decrease A1C levels by as much as 2%
agents capacity Insulin has the potential for greater reduction
to decrease A1C
6. How much BG re- 33-50
duction can 1 unit
of insulin pro-
duce
7. What is another meal time
name for LIspro regular insulin
insulin
8. MOA of sulfony- -*Stimulate insulin release* (inhibiting K+ channel on beta-cells)
lureas They do this by binding to and closing ATP-sensitive potassium (KATP) channels
on the surface of pancreatic beta cells. This prevents potassium from leaving
the cell, which depolarizes it and opens voltage-gated calcium channels. The
resulting increase in intracellular calcium causes insulin granules to fuse with the
cell membrane, which leads to more insulin being secreted
1. candidates for BMI > 40
weight loss BMI > 35 w/ related health conditions
surgery
2. Signs of Addi- hypoglycemia, Na+ and K+ imbalance, weight loss, hypotension, high ACTH levels
son's disease Diffuse hyperpigmentation, loss of axillary hair
3. MOA glipizide Stimulates insulin release from the pancreatic beta cells; reduces glucose output
from the liver; insulin sensitivity is increased at peripheral target sites
4. Sitagliptin ( Janu- Inhibits DPP-4 which reduces the destruction of incretins thereby increases levels
via) MOA of incretin hormones. This increases insulin and decreases blood sugar.
Note- even though it increases insulin- unlikely to cause hypoglycemia!
5. Insulin reducing can only decrease A1C levels by as much as 2%
agents capacity Insulin has the potential for greater reduction
to decrease A1C
6. How much BG re- 33-50
duction can 1 unit
of insulin pro-
duce
7. What is another meal time
name for LIspro regular insulin
insulin
8. MOA of sulfony- -*Stimulate insulin release* (inhibiting K+ channel on beta-cells)
lureas They do this by binding to and closing ATP-sensitive potassium (KATP) channels
on the surface of pancreatic beta cells. This prevents potassium from leaving
the cell, which depolarizes it and opens voltage-gated calcium channels. The
resulting increase in intracellular calcium causes insulin granules to fuse with the
cell membrane, which leads to more insulin being secreted
