NR565 / NR 565 Advanced Pharmacology Midterm Review Study Guide – Care Questions with Accurate Answers (A+ Graded) Expert Solution Updated

MIDTERM EXAM: NR565/ NR 565 ADVANCED PHARMACOLOGY CARE QUESTIONS WITH ACCURATE ANSWERS | MULTIPLE CHOICES A+ GRADED Minimize risk of esophagitis by swallowing the pill whole with a full glass of water, then sitting up for at least 30 min, and taking the med 30 min prior to other intake ..... ANSWER ...... Alendronate Patient Education Interferes with calcium, magnesium, and iron absorption ..... ANSWER ...... Ibandronate Dietary Supplement Interference Alendronate is the first line treatment ..... ANSWER ...... Osteoporosis 1st Line Treatment Safe to use in patients with renal dysfunction or who over produce uric acid ..... ANSWER ...... Allopurinol Safety in Renal Dysfunction Includes CBC with WBC differential, s/s of infection, malignancies, pregnancy rule out, ALT, AST, serum creatinine, comprehensive history and physical exam, and assessment of immunocompetence and liver and renal status ..... ANSWER ...... DMARDs Baseline Diagnostics 2 | P a g e Includes chest x-ray with emphasis on pulmonary and GI status ..... ANSWER ...... Methotrexate Baseline Data Hydroxychloroquine ..... ANSWER ...... DMARD Requiring Ophthalmologic and Cardiac Exam Risk for venous thromboembolic events (DVT, PE, stroke) ..... ANSWER ...... Raloxifene Black Box Warning Reinforcing properties of drugs, physical and physiological dependence, social factors, drug availability, individual vulnerability, impulsivity, low tolerance for frustration, and specific personality disorders ..... ANSWER ...... Controlled Substance Addiction Predictors Adjuvant analgesic for neuropathic pain, effective in diabetic neuropathy, seizures, central neuropathy, postherpetic neuralgia, and fibromyalgia ..... ANSWER ...... Pregabalin Chronic Pain Treatment Sedation, drowsiness, dizziness, ataxia, blurred vision, and difficulty thinking ..... ANSWER ...... Pregabalin Adverse Effects Linked to COX-2 inhibitors and NSAIDs ..... ANSWER ...... GI Bleeding Link 3 | P a g e Start taking this medicine at the first sign of the attack for best results, stop taking this medicine as soon as the pain is relieved or at the first sign of nausea, vomiting, stomach pain, or diarrhea ..... ANSWER ...... Colchicine Patient Education Methotrexate, leflunomide, and biologics like anti-TNF agents, rituximab, and abatacept ..... ANSWER ...... RA High Risk Drugs in Pregnancy NSAIDs, corticosteroids, and several DMARDs including sulfasalazine and hydroxychloroquine ..... ANSWER ...... RA Safe Drugs in Pregnancy May increase the risk for myocardial infarction, stroke, and other thromboembolic events, as well as dangerous gastrointestinal adverse effects such as bleeding, ulceration, and perforation ..... ANSWER ...... NSAID Black Box Warning Interacts with mercaptopurine and azathioprine, warfarin, theophylline, and ampicillin ..... ANSWER ...... Allopurinol Drug Interactions Takes 3 to 6 weeks for symptoms to improve, and 12 weeks or longer for full benefit ..... ANSWER ...... Methotrexate Therapeutic Response