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IFM review course Questions with Detailed Verified
Answers
Non-heme iron sources of food should be pair with ____ to help enhance absorption Ans: ✓ ✓ ✓
Vitamin C rich foods
what are clinical signs of Zinc deficiency? Ans: ✓ ✓ ✓ dermatitis, hair loss, frequent infection,
glossitis, nail dystrophy
Low Zinc is paired with what on labs? Ans: ✓ ✓ ✓ high copper, low Alk phos
Jaundice after fasting is most indicative of a genetic weakness in which biotransformation pathway?
Ans: ✓ ✓ ✓ glucuronidation
Gilberts is a SNP in what? Ans: ✓ ✓ ✓ UGT 1a — impairs gluruonidation
Cigarette smoking induces what CYP enzyme? Ans: ✓ ✓ ✓ CYP1a2
Which mineral is a cofactor for ALL CYP p450 enzymes Ans: ✓ ✓ ✓ iron
What are the types of phase 1 reactions Ans: ✓ ✓ ✓ Oxidation, reduction, hydrolysis, lipolysis
What are the types of phase 2 reactions Ans: ✓ ✓ ✓ Glutathione conjunction, AA conjugation,
methylation, sulfating, acetylation, glucuronidation
Which CYP enzyme metabolizes 40-45% of drugs & hormones Ans: ✓ ✓ ✓ 3A4
Which phase 1 enzyme metabolizes 4-oh Ans: ✓ ✓ ✓ 1B1
Which enzyme metabolizes caffeine Ans: ✓ ✓ ✓ CYP 1A2
What does Gilbert's syndrome patients have an impaired ability to do? Ans: ✓ ✓ ✓ Conjugate
bilirubin with glucuronidation
Which mineral is a required co-factor for all CYP enzymes> Ans: ✓ ✓ ✓ Iron
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__ deficiency is seen with: dermatitis, hair loss, frequent infection, glossitis Ans: ✓ ✓ ✓ Zinc
What types of patients cases have sulfation issues? Ans: ✓ ✓ ✓ Chemical sensitivity, Alzheimer's,
Parkinson's, RA, delayed food sensitivity, diet responsive autism, Tylenol intolerance.
High levels of CYPa12 activity are associated with ? In smokers Ans: ✓ ✓ ✓ Colon cancers
What SNP does Gilbert's have? Ans: ✓ ✓ ✓ UGT1a
Non-heme iron needs ? To enhance absorption Ans: ✓ ✓ ✓ Vitamin c
What meds should Gilberts syndrome avoid? Ans: ✓ ✓ ✓ acetaminophen
What are some signs of poor glucuronidation? Ans: ✓ ✓ ✓ Dysbiosis, high Beta-glucuronidase
How can you look for sulfonation issues? Ans: ✓ ✓ ✓ Sulfur AA: methionine, cystathionine,
cysteine
What does glucuronidation work on? Ans: ✓ ✓ ✓ Bilirubin, steroid/thyroid hormones,
prostaglandins, bile acids and lipophilic xenobiotics
How do we support sulfation? Ans: ✓ ✓ ✓ High sulfur foods (seafood). Sulfur AA (methionine,
NAC, Taurine), MSM
Loss of vibratory sense can be seen with what phase 2 issue? Ans: ✓ ✓ ✓ Methylation
What are some labs to check for low glutathione Ans: ✓ ✓ ✓ RBC glutathione, blood glutathione
peroxidase, serum/plasma cysteine and urine mercapturic acid (would be low)
___ deficiency is seen with: pale tongue, cheek, conjunctiva, angular stomatitis, glossitis, fingernails
ridging/brittle/spoon shaped, pale nail beds Ans: ✓ ✓ ✓ Iron
What are supportive nutrients for glucuronidation? Ans: ✓ ✓ ✓ Ca D-glucarate, quercetin,
probiotics, EFAs, Mg
What is low alk phos seen with? Ans: ✓ ✓ ✓ Zinc deficiency
What inhibits the absorption of iron? Ans: ✓ ✓ ✓ Phytic acid
What are some beta-glucuronidase inhibitors? Ans: ✓ ✓ ✓ Calcium D-glucarate, silymarin, black
currant, reishi, DGL, probiotics, prebiotic foods (inulin)
© Get it right 2025 Getaway - Stuvia US All rights reserved
IFM review course Questions with Detailed Verified
Answers
Non-heme iron sources of food should be pair with ____ to help enhance absorption Ans: ✓ ✓ ✓
Vitamin C rich foods
what are clinical signs of Zinc deficiency? Ans: ✓ ✓ ✓ dermatitis, hair loss, frequent infection,
glossitis, nail dystrophy
Low Zinc is paired with what on labs? Ans: ✓ ✓ ✓ high copper, low Alk phos
Jaundice after fasting is most indicative of a genetic weakness in which biotransformation pathway?
Ans: ✓ ✓ ✓ glucuronidation
Gilberts is a SNP in what? Ans: ✓ ✓ ✓ UGT 1a — impairs gluruonidation
Cigarette smoking induces what CYP enzyme? Ans: ✓ ✓ ✓ CYP1a2
Which mineral is a cofactor for ALL CYP p450 enzymes Ans: ✓ ✓ ✓ iron
What are the types of phase 1 reactions Ans: ✓ ✓ ✓ Oxidation, reduction, hydrolysis, lipolysis
What are the types of phase 2 reactions Ans: ✓ ✓ ✓ Glutathione conjunction, AA conjugation,
methylation, sulfating, acetylation, glucuronidation
Which CYP enzyme metabolizes 40-45% of drugs & hormones Ans: ✓ ✓ ✓ 3A4
Which phase 1 enzyme metabolizes 4-oh Ans: ✓ ✓ ✓ 1B1
Which enzyme metabolizes caffeine Ans: ✓ ✓ ✓ CYP 1A2
What does Gilbert's syndrome patients have an impaired ability to do? Ans: ✓ ✓ ✓ Conjugate
bilirubin with glucuronidation
Which mineral is a required co-factor for all CYP enzymes> Ans: ✓ ✓ ✓ Iron
© Get it right 2025 Getaway - Stuvia US All rights reserved
, Click here for more: Scholars nexus
__ deficiency is seen with: dermatitis, hair loss, frequent infection, glossitis Ans: ✓ ✓ ✓ Zinc
What types of patients cases have sulfation issues? Ans: ✓ ✓ ✓ Chemical sensitivity, Alzheimer's,
Parkinson's, RA, delayed food sensitivity, diet responsive autism, Tylenol intolerance.
High levels of CYPa12 activity are associated with ? In smokers Ans: ✓ ✓ ✓ Colon cancers
What SNP does Gilbert's have? Ans: ✓ ✓ ✓ UGT1a
Non-heme iron needs ? To enhance absorption Ans: ✓ ✓ ✓ Vitamin c
What meds should Gilberts syndrome avoid? Ans: ✓ ✓ ✓ acetaminophen
What are some signs of poor glucuronidation? Ans: ✓ ✓ ✓ Dysbiosis, high Beta-glucuronidase
How can you look for sulfonation issues? Ans: ✓ ✓ ✓ Sulfur AA: methionine, cystathionine,
cysteine
What does glucuronidation work on? Ans: ✓ ✓ ✓ Bilirubin, steroid/thyroid hormones,
prostaglandins, bile acids and lipophilic xenobiotics
How do we support sulfation? Ans: ✓ ✓ ✓ High sulfur foods (seafood). Sulfur AA (methionine,
NAC, Taurine), MSM
Loss of vibratory sense can be seen with what phase 2 issue? Ans: ✓ ✓ ✓ Methylation
What are some labs to check for low glutathione Ans: ✓ ✓ ✓ RBC glutathione, blood glutathione
peroxidase, serum/plasma cysteine and urine mercapturic acid (would be low)
___ deficiency is seen with: pale tongue, cheek, conjunctiva, angular stomatitis, glossitis, fingernails
ridging/brittle/spoon shaped, pale nail beds Ans: ✓ ✓ ✓ Iron
What are supportive nutrients for glucuronidation? Ans: ✓ ✓ ✓ Ca D-glucarate, quercetin,
probiotics, EFAs, Mg
What is low alk phos seen with? Ans: ✓ ✓ ✓ Zinc deficiency
What inhibits the absorption of iron? Ans: ✓ ✓ ✓ Phytic acid
What are some beta-glucuronidase inhibitors? Ans: ✓ ✓ ✓ Calcium D-glucarate, silymarin, black
currant, reishi, DGL, probiotics, prebiotic foods (inulin)
© Get it right 2025 Getaway - Stuvia US All rights reserved
