BIO 260- Mitosis and Meiosis
1. Prokaryote Cell Division: Copy DNA and divide via binary fission
-DNA circular (necklace) chromosome
2. Virus Cell Division: require host to divide
-protein coat and nucleic acids
3. Chromosome Structure in Eukaryotes: Linear DNA
No Plasmids
Associated with histone proteins
Cell contains two or more chromosome types
-only observable during mitosis/meiosis
4. 1. Centromere
2. Telomeres
3. Origins of replication regions: The 3 essential parts of a chromosome
5. Centromere: attachment point for spindle fibers,
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, -has kinetochore and spindle fibers
6. Kinetochore: A protein complex on a specialized region on the centromere that links each sister chromatid to
the mitotic spindle.
7. Spindle Fibers: attach to both Centromere and Kinetochore
8. Telomeres: DNA at the tips of chromosomes
-degrade w/ each cell division; aging
9. Hayflick limit: The number of times a human cell is capable of dividing into two new cells. The limit for most
a specific
human cells is approximately 50 divisions, an indication that the life span is limited by our genetic program.
10. Origins of Replication: Site where the replication of a DNA molecule begins, consisting of
sequence of nucleotides.
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1. Prokaryote Cell Division: Copy DNA and divide via binary fission
-DNA circular (necklace) chromosome
2. Virus Cell Division: require host to divide
-protein coat and nucleic acids
3. Chromosome Structure in Eukaryotes: Linear DNA
No Plasmids
Associated with histone proteins
Cell contains two or more chromosome types
-only observable during mitosis/meiosis
4. 1. Centromere
2. Telomeres
3. Origins of replication regions: The 3 essential parts of a chromosome
5. Centromere: attachment point for spindle fibers,
1/6
, -has kinetochore and spindle fibers
6. Kinetochore: A protein complex on a specialized region on the centromere that links each sister chromatid to
the mitotic spindle.
7. Spindle Fibers: attach to both Centromere and Kinetochore
8. Telomeres: DNA at the tips of chromosomes
-degrade w/ each cell division; aging
9. Hayflick limit: The number of times a human cell is capable of dividing into two new cells. The limit for most
a specific
human cells is approximately 50 divisions, an indication that the life span is limited by our genetic program.
10. Origins of Replication: Site where the replication of a DNA molecule begins, consisting of
sequence of nucleotides.
2/6
