10/8/25, 1:54 AM Step 1 USMLE-RX #2 Flashcards | Quizlet
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Anatomy 2 - Week 2 Lab Objectives... Blood Types, Antigens, and Compati... NUR 211 Test 3 Study Guide Referen
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Terms in this set (1425)
Granulocyte: time to mature in bone 6-10 days
marrow?
Granulocyte: time spent in circulation? 6-10 hours
Granulocyte: time spent in peripheral 1-4 days
tissues?
Erythrocyte (RBC): time spent in 110-120 days
circulation?L-12
Platelet (thrombocyte): time spent in 8-10 days
circulation?
Platelet (thrombocyte): derived from Megakaryocytes
Monocyte: time spent in circulation? 1-3 days
Defect of NADPH Oxidase
Chronic Granulomatous Disease (CGD):
defect?
Thus are unable to produce a robust respiratory burst in neutrophils
Ferritin: function? binds free iron and stores it intracellularly
TIBC & Ferritin will be opposite
TIBC & Ferritin: how do they correlate?
If Ferritin is LOW then TIBC will be HIGH (Ferritin is low if Iron is low because Ferritin
can't bind iron if it is low)
Low MCV
Low Iron
Low Ferritin
Iron deficiency Anemia: lab values?
High TIBC
Hypochromasia (central pallor)
Pregnancy: anemia often associated with? Iron Deficiency Anemia
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, 10/8/25, 1:54 AM Step 1 USMLE-RX #2 Flashcards | Quizlet
-fatigue
-conjunctival pallor
Iron Deficiency Anemia: symptoms?
-Pica
-spoon nails (koilonychia)
spoon nails
koilonychia aka?
2. Iron Deficiency Anemia
2. Diagnosis
Iron Deficiency Anemia Plummer-Vinson Syndrome
Esophageal Webs
Dysphagia
Breast mass biopsy: proliferation of 1. Fibroadenoma
intralobular stroma distorting the
associated epithelium? (proliferation of intralobular stroma)
1. Diagnosis? BENIGN BREAST TUMOR
-small
-mobile
Fibroadenoma: characteristics?
-sharp edges
-DOES NOT METASTASIZE TO LYMPH NODES
HYPERCALCEMIA
Multiple Myeloma: calcium level?
MM is a tumor arising from, it causes BONE LESIONS, WHICH CAUSE
HYPERCALCEMIA.
Multiple Myeloma
Single-file stacking of RBCs
Stacked RBCs (Rouleaux formation)
Stacked RBCs (Rouleaux formation)
Multiple Myeloma: what is seen on blood
smear?
72 yo man with chronic cough comes into 1. Multiple Myeloma
clinic with sharp pain in his ribs that started 2. Hypercalcemia
after he had an episode of severe 3. Plasma Cell
coughing. He has also been feeling very 4. Stacked RBCs (Rouleaux formation)
fatigued lately and has lost 10 lbs in the
past 3 months. Physician orders a chest x- MM must be on the differential in an ELDERLY
ray which reveals a rib fracture. Suspicious, PATIENT WITH PATHOLOGIC FRACTURES.
the physician then orders a bone marrow
biopsy. Results are shown (see image) MM is a bone marrow neoplasm, specifically the
plasma cell. Recognized by their off-center nuclei
1. Diagnosis and clock-face chromatin distribution.
2. Calcium Levels
3. characteristic cell? MM is a tumor arising from, it causes BONE
4. What would be seen on a blood smear? LESIONS, WHICH CAUSE HYPERCALCEMIA.
https://quizlet.com/376328231/step-1-usmle-rx-2-flash-cards/ 2/9
Step 1 USMLE-RX #2 Save
Leave the first rating
Students also studied
Flashcard sets Practice tests
Anatomy 2 - Week 2 Lab Objectives... Blood Types, Antigens, and Compati... NUR 211 Test 3 Study Guide Referen
9 terms 18 terms 35 terms 14 terms
More
pricetheboss Preview Parsa1234542 Preview a_elizabeth_e Preview Sha
Terms in this set (1425)
Granulocyte: time to mature in bone 6-10 days
marrow?
Granulocyte: time spent in circulation? 6-10 hours
Granulocyte: time spent in peripheral 1-4 days
tissues?
Erythrocyte (RBC): time spent in 110-120 days
circulation?L-12
Platelet (thrombocyte): time spent in 8-10 days
circulation?
Platelet (thrombocyte): derived from Megakaryocytes
Monocyte: time spent in circulation? 1-3 days
Defect of NADPH Oxidase
Chronic Granulomatous Disease (CGD):
defect?
Thus are unable to produce a robust respiratory burst in neutrophils
Ferritin: function? binds free iron and stores it intracellularly
TIBC & Ferritin will be opposite
TIBC & Ferritin: how do they correlate?
If Ferritin is LOW then TIBC will be HIGH (Ferritin is low if Iron is low because Ferritin
can't bind iron if it is low)
Low MCV
Low Iron
Low Ferritin
Iron deficiency Anemia: lab values?
High TIBC
Hypochromasia (central pallor)
Pregnancy: anemia often associated with? Iron Deficiency Anemia
https://quizlet.com/376328231/step-1-usmle-rx-2-flash-cards/ 1/9
, 10/8/25, 1:54 AM Step 1 USMLE-RX #2 Flashcards | Quizlet
-fatigue
-conjunctival pallor
Iron Deficiency Anemia: symptoms?
-Pica
-spoon nails (koilonychia)
spoon nails
koilonychia aka?
2. Iron Deficiency Anemia
2. Diagnosis
Iron Deficiency Anemia Plummer-Vinson Syndrome
Esophageal Webs
Dysphagia
Breast mass biopsy: proliferation of 1. Fibroadenoma
intralobular stroma distorting the
associated epithelium? (proliferation of intralobular stroma)
1. Diagnosis? BENIGN BREAST TUMOR
-small
-mobile
Fibroadenoma: characteristics?
-sharp edges
-DOES NOT METASTASIZE TO LYMPH NODES
HYPERCALCEMIA
Multiple Myeloma: calcium level?
MM is a tumor arising from, it causes BONE LESIONS, WHICH CAUSE
HYPERCALCEMIA.
Multiple Myeloma
Single-file stacking of RBCs
Stacked RBCs (Rouleaux formation)
Stacked RBCs (Rouleaux formation)
Multiple Myeloma: what is seen on blood
smear?
72 yo man with chronic cough comes into 1. Multiple Myeloma
clinic with sharp pain in his ribs that started 2. Hypercalcemia
after he had an episode of severe 3. Plasma Cell
coughing. He has also been feeling very 4. Stacked RBCs (Rouleaux formation)
fatigued lately and has lost 10 lbs in the
past 3 months. Physician orders a chest x- MM must be on the differential in an ELDERLY
ray which reveals a rib fracture. Suspicious, PATIENT WITH PATHOLOGIC FRACTURES.
the physician then orders a bone marrow
biopsy. Results are shown (see image) MM is a bone marrow neoplasm, specifically the
plasma cell. Recognized by their off-center nuclei
1. Diagnosis and clock-face chromatin distribution.
2. Calcium Levels
3. characteristic cell? MM is a tumor arising from, it causes BONE
4. What would be seen on a blood smear? LESIONS, WHICH CAUSE HYPERCALCEMIA.
https://quizlet.com/376328231/step-1-usmle-rx-2-flash-cards/ 2/9
