Maryville University Nurs615 Pharm Exam 1 With Correct Solutions Verified.

MARYVILLE UNIVERSITY: NURS615 PHARM EXAM 1 COMPLETE QUESTIONS & n n n n n n n n




ANSWERS (100% VERIFIED SOLUTIONS)2025/2026 UPDATE n n n n n




Clinical Judgement - CORRECT ANSWER -Conclusion/opinion at which a nurse arrives following a
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process of observation, reflection, & analysis of observable or available information or data.
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*must gather data to make diagnosis, must have diagnosis to select and start treatment
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WHO 6-Step Model of Rational Prescribing - CORRECT ANSWER -1. Define patient's problem (diagnose)
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2. Specify the therapeutic objective (goal) n n n n




3. Choose treatment n




4. Start treatment n




5. Educate the patient n n




6. Monitor the effectiveness n n




Criteria for choosing an effective drug
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"I Can PresCribe A Drug" Mnemonic - CORRECT ANSWER -I=indication C=contraindication
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P=precautions

C=cost/compliance

E=efficacy
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A=adverse effects n




n D=dose/duration/direction



Role of FDA - CORRECT ANSWER -Ensures the safety, efficacy, and security of human and
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veterinary drugs, biological products, and medical devices. As well as food, cosmetics, and products
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that emit radiation.
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,What is the role of the FDA in regard to supplements and vitamins? - CORRECT ANSWER -Does NOT
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protect or ensure the safety of supplements and vitamins. They have certain rules, but they aren't as
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stringent like they are for drugs.
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What can St. John's wort interact with? - CORRECT ANSWER -SSRI, CNS drugs, MAOI, SSNRI, steroids,
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caffeine, and anticoagulants.
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Off-label prescribing - CORRECT ANSWER -medication is being used in a manner not specified in the
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FDAs approved packaging label/insert.
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*different route, dose, or indication n n n n




Pharmacotherapeutics - CORRECT ANSWER -study of therapeutic uses and effects of drugs. n n n n n n n n n n n




Beneficial and adverse drug reactions.
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Pharmacodynamics - CORRECT ANSWER -what the drug does to the body n n n n n n n n n n




Agonist - CORRECT ANSWER -binds to a receptor & produces a response/stimulates (full
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activation)
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Antagonist - CORRECT ANSWER -Binds & blocks activity (no activation)
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Can a drug be an agonist and antagonist? - CORRECT ANSWER -Yes. In this case, they do both actions
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to have less activation, versus full or no activation.
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Pharmacokinetics - CORRECT ANSWER -what the body does to the drug (ADME) n n n n n n n n n n n




What is ADME in pharmacokinetics? - CORRECT ANSWER -absorption, distribution, metabolism,
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excretion
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, Absorption - CORRECT ANSWER -first step, occurs after medication administration
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What does absorption depend on? - CORRECT ANSWER -routes of administration, pH and
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membrane penetration
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What percentage of rectal drugs go through first-pass metabolism? - CORRECT ANSWER -50%
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Membrane penetration involves what? - CORRECT ANSWER -lipid solubility and ionization
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How does pH affect absorption? - CORRECT ANSWER -If the pH of the stomach is altered, in oral
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medication administration, the medication can be absorbed too soon or not soon enough.
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Why can't you crush enteric coated medications? - CORRECT ANSWER -This interferes with absorption, it
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will not absorb where intended.
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Ionization - CORRECT ANSWER -the charge of the molecule/drug. Ionized
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n = charged (polar)
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non-ionized = uncharged (non-polar) n n n




Lipophilic - CORRECT ANSWER -*Lipid loving, uncharged (non-polar/non-ionized), small in size.
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*crosses membranes more easily than hydrophilic
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How do lipophilic drugs cross membranes? - CORRECT ANSWER -Passive diffusion. Most cell membranes
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are lipophilic, making it easier for lipophilic drugs to cross.
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