Page | 1
CLM final Questions with Detailed Verified
Answers
how long do troponins stay elevated post MI Ans: 10 days
when do troponins peak Ans: 14-18 hours
benefit to delayed elevation of troponins Ans: detection if someone has delayed
treatment
disadvantage of delayed elevation of troponins Ans: cant asses another infarction
what can assess an infarction sooner than 10 days Ans: CK-MB
how long before ck-mb returns to normal Ans: 24-36 hours
disadvantage of ckmb Ans: not early marker (peak at 24 hours)
ckmd first detected Ans: 4-6 hours
what is hs-CRP useful in Ans: risk stratification for cad and ascvd
what are biomarkers of inflam associated with Ans: cardiac ischemia
Hs-crp is directly involved in Ans: coronary plaque atherogenesis
, Page | 2
who should get a hscrp Ans: metabolically stable patient free of infection of acute
illness and intermediate cv risk
what can you do with a hscrp Ans: id patients that are more likely to benefit from
more aggressive interventions
what do hs-CRp levels correlate with Ans: modestly with atherosclerosis
increased for plaque disruption or thrombosis
what is NT-proBNP Ans: nonpharm active peptide derived from cleavage of
myocardium in response to myocardial stress or fluid overload
why use NT-proBNP if no specific advantages Ans: is standardized compared to BNP
bnp should not be used Ans: alone or indiscriminately as a screening tool
how is a proBNP Ans: very sensitive not specific
what can elevate a bnp besides heart failure Ans: renal failure
pulm htn
cirrhosis
myocarditis
elderly
meds
, Page | 3
when a bnp most useful Ans: if negative or elevated and already suspicious
when is a bnp not useful Ans: renal failure patients
what can elevate homocysteine Ans: genetics
vitb12,6 folate def
ckd
fibrates, nicotinic acid, metformin, methotrexate
smoking
what is hyperhomocysteine associated with Ans: arthrogenic and prothrombogenic
properties
is homocysteine generally recommended Ans: not routinely
whats in a lipid panel Ans: total cholesterol
HDL
TG
can measure lipoprotein (Lpa)
what values are calculated Ans: LDL (can be ordered but not usually)
total cholesterol/HDL
cardiac risk
CLM final Questions with Detailed Verified
Answers
how long do troponins stay elevated post MI Ans: 10 days
when do troponins peak Ans: 14-18 hours
benefit to delayed elevation of troponins Ans: detection if someone has delayed
treatment
disadvantage of delayed elevation of troponins Ans: cant asses another infarction
what can assess an infarction sooner than 10 days Ans: CK-MB
how long before ck-mb returns to normal Ans: 24-36 hours
disadvantage of ckmb Ans: not early marker (peak at 24 hours)
ckmd first detected Ans: 4-6 hours
what is hs-CRP useful in Ans: risk stratification for cad and ascvd
what are biomarkers of inflam associated with Ans: cardiac ischemia
Hs-crp is directly involved in Ans: coronary plaque atherogenesis
, Page | 2
who should get a hscrp Ans: metabolically stable patient free of infection of acute
illness and intermediate cv risk
what can you do with a hscrp Ans: id patients that are more likely to benefit from
more aggressive interventions
what do hs-CRp levels correlate with Ans: modestly with atherosclerosis
increased for plaque disruption or thrombosis
what is NT-proBNP Ans: nonpharm active peptide derived from cleavage of
myocardium in response to myocardial stress or fluid overload
why use NT-proBNP if no specific advantages Ans: is standardized compared to BNP
bnp should not be used Ans: alone or indiscriminately as a screening tool
how is a proBNP Ans: very sensitive not specific
what can elevate a bnp besides heart failure Ans: renal failure
pulm htn
cirrhosis
myocarditis
elderly
meds
, Page | 3
when a bnp most useful Ans: if negative or elevated and already suspicious
when is a bnp not useful Ans: renal failure patients
what can elevate homocysteine Ans: genetics
vitb12,6 folate def
ckd
fibrates, nicotinic acid, metformin, methotrexate
smoking
what is hyperhomocysteine associated with Ans: arthrogenic and prothrombogenic
properties
is homocysteine generally recommended Ans: not routinely
whats in a lipid panel Ans: total cholesterol
HDL
TG
can measure lipoprotein (Lpa)
what values are calculated Ans: LDL (can be ordered but not usually)
total cholesterol/HDL
cardiac risk