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Exam (elaborations)

CLM final Questions with Detailed Verified Answers

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CLM final Questions with Detailed Verified Answers

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CLM final Questions with Detailed Verified
Answers



how long do troponins stay elevated post MI Ans: 10 days


when do troponins peak Ans: 14-18 hours


benefit to delayed elevation of troponins Ans: detection if someone has delayed

treatment


disadvantage of delayed elevation of troponins Ans: cant asses another infarction


what can assess an infarction sooner than 10 days Ans: CK-MB


how long before ck-mb returns to normal Ans: 24-36 hours


disadvantage of ckmb Ans: not early marker (peak at 24 hours)


ckmd first detected Ans: 4-6 hours


what is hs-CRP useful in Ans: risk stratification for cad and ascvd


what are biomarkers of inflam associated with Ans: cardiac ischemia


Hs-crp is directly involved in Ans: coronary plaque atherogenesis

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who should get a hscrp Ans: metabolically stable patient free of infection of acute

illness and intermediate cv risk


what can you do with a hscrp Ans: id patients that are more likely to benefit from

more aggressive interventions


what do hs-CRp levels correlate with Ans: modestly with atherosclerosis


increased for plaque disruption or thrombosis


what is NT-proBNP Ans: nonpharm active peptide derived from cleavage of

myocardium in response to myocardial stress or fluid overload


why use NT-proBNP if no specific advantages Ans: is standardized compared to BNP


bnp should not be used Ans: alone or indiscriminately as a screening tool


how is a proBNP Ans: very sensitive not specific


what can elevate a bnp besides heart failure Ans: renal failure


pulm htn


cirrhosis


myocarditis


elderly


meds

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when a bnp most useful Ans: if negative or elevated and already suspicious


when is a bnp not useful Ans: renal failure patients


what can elevate homocysteine Ans: genetics


vitb12,6 folate def


ckd


fibrates, nicotinic acid, metformin, methotrexate


smoking


what is hyperhomocysteine associated with Ans: arthrogenic and prothrombogenic

properties


is homocysteine generally recommended Ans: not routinely


whats in a lipid panel Ans: total cholesterol


HDL


TG


can measure lipoprotein (Lpa)


what values are calculated Ans: LDL (can be ordered but not usually)


total cholesterol/HDL


cardiac risk

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