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FSC100 Exam review UPDATED ACTUAL Questions and CORRECT Answers

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FSC100 Exam review UPDATED ACTUAL Questions and CORRECT Answers

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FSC100 Exam review UPDATED ACTUAL Questions and CORRECT Answers

1. Forensic biology - Bodily fluid identification (serology)
incorporates re- - Deoxyribonucleic acid (DNA) analysis
lated areas of

2. Serology -Techniques are used to screen evidence items for the prescience and type of
body fluid disposition
- analyses and targets a the biochemicals and cells that define distinctive func-
tional characteristics of different body fluids: hemoglobin in blood and sperma-
tozoa in semen

3. Deoxyribonucleic genetic information that dictates the firm and development of an organism. A
acid molecule found in almost all human cells

4. DNA is the genetic Life
blueprint of:

5. Each strand of the long chains of nucleotides, composedof a phosphate group, a type of sugar
helix is composed called deoyribose, and one of four nitrogen-containing bases
of:

6. 4 bases of DNA Adenine(A), Thymine(T), Guanine(G), Cytosine(C)`

7. What 2 sub- - Adenine(A) with Thymine(T)
units form base - Guanine(G) with Cytosine(C)
pairs(BP)

8. Strands of DNA proteins (genes) that provide genetic information in the organism, like hair color,
form codes of: height, hair texture and skin

9. Human DNA con- 3 billion total number of base pairs
tain approx.:

10. Chromosomes structures carrying molecular strands of DNA

,11. Genome one cell collection of chromosomes

12. Humans inherit: a genome of 23 chromosomes from each parent for a total of 46.

13. Rosalind Franklin - died at 36
- contributions to understanding DNA, including RNA viruses coal and graphite
- found being female is significant as oppurtunities were limited to women
chemical structure of DNA similarly to all cellular organisms.

14. First DNA case - Narborough England
- rape and murder of 2, 15yo girls
- in ealry 1980, Dr Jeffery's lab produced first "restricition fragment Length
polymorphism" = RFLP

15. Dr Alec Jeffery - Studied at Leicester University - England
- studying DNA variations and the evolution of gene families
- his interest and goal was to develop markers (a type of identification tag) to
track the position of these genes

16. RFLP Restriction Fragment Length Polymorphism
- Created 1980 in Dr. Jeffery's lab
- a molecular method of genetic analysis that allows individuals to be identified
based on unique patterns of restriction enzyme cutting in specific regions of DNA

17. 1984 Jefferys developed and used the first DNA tests to be applied to a criminal case

18. DNA Fingerprint- - first-generation typing system made by Dr.Jefferys.
ing - this method looks at sections of DNA located in different regions on different
chromosomes
- multilocus typing system

19. DNA typing describes the system of assessing variations in sections of DNA for analysis

20. DNA profiling



, the second generation typing system (a more recent development) that looks at
one area- a single locus- on a single chromosome. this is the method now in use
for forensic analysis

21. DNA profile most simply viewed as a set of numbers representing the DNA 'variants' as target
locations

22. DNA locations also known as 'Loci' and are the genetic equivalents of addresses or postal codes

23. genetic differ- variants or alleles
ences at loci are:

24. STR analysis a method of DNA profiling that compares the lengths of STR sequences at specific
sites in the genome

25. Regions with re- variable number tandem repeats
peats of nine to
eighty base pairs
are referred to as:

26. Regions contain- short tandem repeats
ing 2 to 5 base
pair repeats are:

27. today robotics solid-phase
use
technologies that
openbiological
cells, selectively
bind DNA to
magnetic beads,
and then wash off
the non-DNA



, components,
leaving the
purified DNA for
further analysis

28. DNA standards - introduced in 1988
and protocols - arguments by scientists over practical applications and statistical calculations
- 1990s saw rapid increase in acceptance and usage
- by 1994, typing was firmly established from use in forensic investigations

29. CODIS - The DNA database (FBI - textbook)
- a database that stores DNA profiles of convicted individuals.

30. Double indexing - convicted offender index (contains sex offenders and other violent crimes)
system of DNA - Forensic index: contains profiles developed from crime scene evidence such as
profiles blood and semen

31. DNA identifica- 1998
tion act enacted
in:

32. DNA idetification - permitted the formation of the national DNA databank
act - allowed judges to request blood, buccal or hair samples. this legislation
became oflcial on june 30th 2000

33. Biological sam- legal investigations
ples from convict-
ed offenders can
only be for:

34. DNA is taken from upon conviction, not arrest
offender:

35. DNA reliability

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