Chamberlain Nr507 Midterm Exam Exam Questions With Correct Verified Answers | 100% Pass (A+ Certified)

CHAMBERLAIN NR507 MIDTERM EXAM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS | 100% PASS (A+ CERTIFIED) 1. Type 1 Hypersensitivity Reaction Correct Answer "Allergic reaction" - Mediated by IgE. - Inflammation d/t mast cell degranulation. - Hay fever, hives (uticaria). - Local s/s: itching, rash. - Systemic: wheezing. - Severe, systemic reaction: anaphylaxis: hypotension, severe bronchoconstriction. - Main tx: epinephrine. 2. Type 2 Hypersensitivity Reaction Correct Answer Cytotoxic reaction; tissue specific - Macrophages are the primary effectors cells involved - Causes tissue damage or alters function - Examples: 1) Grave's disease- example of altering thyroid function, doesn't destroy thyroid tissue. 2) ABO incompatibility- example of cell/tissue damage; severe transfusion reaction 2 / 17 occurs & the transfused erythrocytes are destroyed by agglutination or complement-mediated lysis. 3. Difference between type 2 & 3 hypersensitivity reactions Correct Answer Type 2: organ specific; antibody binds to the antigen on the cell surface. - Type 3: not organ specific; antibody binds to soluble antigen outside the cell surface that was released into the blood or body fluids, and the complex is then deposited in the tissues. 4. Type 3 Hypersensitivity Reaction Correct Answer Immune complex - Antigen-antibody complex deposited in the tissues - Neutrophils are the primary effector cell - Causes autoimmune diseases - Examples: rheumatoid arthritis (joints), systemic lupus erythematosus (SLE, organs) 5. Systemic Lupus Erythematosus (SLE) Correct Answer Facial rash confined to the cheeks (malar rash) -