HNG 540 Exam 1
1. Q: A patient's nutritional intake and laboratory results A: Distribution of drugs to
reflect hypoalbuminemia. This is critical to prescribing target tissue may be af-
because fected.
2. Q: Drugs that have a significant first-pass effect A: Are rapidly metabolized
by the liver and may have
little if any desired action.
3. Q: The route of excretion of a volatile drug will likely be A: Lungs.
the
4. Q: Medroxyprogesterone (Depo Provera) is prescribed A: Increase the length of
intramuscularly (IM) to create a storage reservoir of time a drug is available
the drug. Storage reservoirs and active.
5. Q: The NP chooses to give cephalexin every 8 hours A: Biological half-life.
based on knowledge of the drug's
6. Q: Azithromycin dosing requires that the first day's A: Rapidly achieves drug
dosage be twice those of the other 4 days of the pre- levels in the therapeutic
scription. This is considered a loading dose. A loading range.
dose
7. Q: The point in time on the drug concentration curve A: Onset of action.
that indicates the first sign of a therapeutic effect is the
8. Q: Phenytoin requires that a trough level be drawn. A: To determine if a drug is
Peak and trough levels are done in the therapeutic range.
9. Q: A laboratory result indicates that the peak level for A: Concentration will pro-
a drug is above the minimum toxic concentration. This duce an adverse response.
means that the
10.
, HNG 540 Exam 1
Q: Drugs that are receptor agonists may demonstrate A: Desensitization or
what property? downregulation with con-
tinuous use.
11. Q: Drugs that are receptor antagonists such as beta blockers, may
cause, A: An exaggerated
response if abruptly dis-
continued.
12. Q: Factors that affect gastric drug absorption include A: Lipid solubility of the
drug.
13. Q: Drugs administered via IV A: Begin distribution into
the body immediately.
14. Q: When a medication is added to a regimen for a the combined effect of the
synergistic effect drugs is, A: Greater than
the sum of the effects of
each drug individually.
15. Q: Which of the following statements about bioavail- A: Bioavailability issues
ability is true? are especially important
for drugs with narrow
therapeutic ranges or
sustained-release mecha-
nisms.
16. Q: Which of the following statements about the major A: The blood-brain barri-
distribution barriers (blood-brain or fetal-placental) is er slows the entry of many
true? drugs into and from brain
cells.
17.
1. Q: A patient's nutritional intake and laboratory results A: Distribution of drugs to
reflect hypoalbuminemia. This is critical to prescribing target tissue may be af-
because fected.
2. Q: Drugs that have a significant first-pass effect A: Are rapidly metabolized
by the liver and may have
little if any desired action.
3. Q: The route of excretion of a volatile drug will likely be A: Lungs.
the
4. Q: Medroxyprogesterone (Depo Provera) is prescribed A: Increase the length of
intramuscularly (IM) to create a storage reservoir of time a drug is available
the drug. Storage reservoirs and active.
5. Q: The NP chooses to give cephalexin every 8 hours A: Biological half-life.
based on knowledge of the drug's
6. Q: Azithromycin dosing requires that the first day's A: Rapidly achieves drug
dosage be twice those of the other 4 days of the pre- levels in the therapeutic
scription. This is considered a loading dose. A loading range.
dose
7. Q: The point in time on the drug concentration curve A: Onset of action.
that indicates the first sign of a therapeutic effect is the
8. Q: Phenytoin requires that a trough level be drawn. A: To determine if a drug is
Peak and trough levels are done in the therapeutic range.
9. Q: A laboratory result indicates that the peak level for A: Concentration will pro-
a drug is above the minimum toxic concentration. This duce an adverse response.
means that the
10.
, HNG 540 Exam 1
Q: Drugs that are receptor agonists may demonstrate A: Desensitization or
what property? downregulation with con-
tinuous use.
11. Q: Drugs that are receptor antagonists such as beta blockers, may
cause, A: An exaggerated
response if abruptly dis-
continued.
12. Q: Factors that affect gastric drug absorption include A: Lipid solubility of the
drug.
13. Q: Drugs administered via IV A: Begin distribution into
the body immediately.
14. Q: When a medication is added to a regimen for a the combined effect of the
synergistic effect drugs is, A: Greater than
the sum of the effects of
each drug individually.
15. Q: Which of the following statements about bioavail- A: Bioavailability issues
ability is true? are especially important
for drugs with narrow
therapeutic ranges or
sustained-release mecha-
nisms.
16. Q: Which of the following statements about the major A: The blood-brain barri-
distribution barriers (blood-brain or fetal-placental) is er slows the entry of many
true? drugs into and from brain
cells.
17.
