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HESI RN Pharmacology Q-Bank 2025–2026 Edition – Verified Questions with Rationales A+

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This HESI RN Pharmacology Q-Bank for 2025–2026 provides verified questions with detailed rationales to help nursing students prepare effectively for the HESI RN exam. Covering medications, pharmacokinetics, drug classifications, patient safety, and clinical application, this resource strengthens understanding, reinforces critical thinking, and enhances exam readiness. Trusted by nursing students, HealthStudyPro’s Q-Bank ensures accurate, up-to-date content for guaranteed success in pharmacology sections of the HESI RN exam.

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🩺 HESI RN Pharmacology Q-Bank – 2025–2026 Edition

Verified Questions with Detailed Rationales

HealthStudyPro | Trusted Nursing Exam Support

,Question 1

A gnurse gis gadministering gfurosemide g(Lasix) gto ga gclient gwith gheart gfailure. gWhich
gelectrolyte gimbalance gshould gthe gnurse gmonitor gmost gclosely?


A. gHyperkalemia
B. gHypokalemia g✅
C. gHypernatremia
D. gHypocalcemia

✅ gCorrect gAnswer: gB. gHypokalemia

🧠 gRationale:
Furosemide gis ga gloop gdiuretic gthat gcauses gpotassium gexcretion. gThe gnurse gshould gmonitor
gfor ghypokalemia, gwhich gcan gcause gmuscle gcramps, gweakness, gor gcardiac gdysrhythmias.




Question g2

A gclient gis gprescribed gwarfarin g(Coumadin). gWhich gof gthe gfollowing ginstructions gis gmost
gimportant gfor gthe gnurse gto ginclude?


A. gAvoid ggreen gleafy gvegetables gentirely
B. gReport gsigns gof gbleeding g✅
C. gTake gwith gantacids gto gprevent gstomach gupset
D. gExpect gyour gurine gto gturn gorange

✅ gCorrect gAnswer: gB. gReport gsigns gof gbleeding

🧠 gRationale:
Warfarin gis gan ganticoagulant. gPatients gshould gbe ginstructed gto gwatch gfor gsigns gof gbleeding
g(bruising, ggum gbleeding, gblack gstools). gVitamin gK gintake gshould gbe gconsistent, gnot
geliminated.




Question g3

A gnurse gis greviewing ga gnew gorder gfor gdigoxin g(Lanoxin). gWhat gis gthe gpriority gnursing
gassessment gbefore gadministering gthe gdrug?


A. gBlood gpressure
B. gRespiratory grate

,C. gApical gpulse g✅
D. gBowel gsounds

✅ gCorrect gAnswer: gC. gApical gpulse

🧠 gRationale:
Digoxin gcan gcause gbradycardia. gThe gapical gpulse gshould gbe gchecked gfor g1 gfull gminute,
gand gthe gdrug gshould gbe gheld gif gthe gheart grate gis g<60 gbpm.




Question g4

Which gadverse geffect gshould gthe gnurse gmonitor gfor gin ga gpatient greceiving ggentamicin?

A. gConstipation
B. gTinnitus g✅
C. gRash
D. gHypertension

✅ gCorrect gAnswer: gB. gTinnitus

🧠 gRationale:
Gentamicin gis gan gaminoglycoside gantibiotic gthat gis gototoxic. gTinnitus, ghearing gloss, gor
gbalance gissues gshould gbe greported gimmediately.




Question g5

A gpatient gtaking glisinopril greports ga gpersistent gdry gcough. gWhat gshould gthe gnurse
ganticipate?


A. gThe gmedication gdose gwill gbe gincreased
B. gThe gpatient gshould gincrease gfluid gintake
C. gThe gmedication gmay gbe gdiscontinued g✅
D. gThis gis gan gexpected gside geffect, gand gno gaction gis gneeded

✅ gCorrect gAnswer: gC. gThe gmedication gmay gbe gdiscontinued

🧠 gRationale:
ACE ginhibitors glike glisinopril gcommonly gcause ga gdry gcough. gIt’s goften gpersistent gand
guncomfortable, gleading gproviders gto gswitch gthe gpatient gto gan gARB g(like glosartan).

, Question g6

Which glab gvalue gshould gbe gmonitored gwhen ga gpatient gis gon gheparin gtherapy?

A. gPT
B. gINR
C. gaPTT g✅
D. gPlatelet gcount

✅ gCorrect gAnswer: gC. gaPTT

🧠 gRationale:
Heparin gaffects gthe gintrinsic gclotting gpathway, gso gaPTT gis gthe gcorrect glab gto gmonitor.
gPT/INR gis gfor gwarfarin.




Question g7

What gis ga gserious gadverse geffect gof gclozapine g(Clozaril)?

A. gHypertension
B. gAgranulocytosis g✅
C. gWeight gloss
D. gUrinary gretention

✅ gCorrect gAnswer: gB. gAgranulocytosis

🧠 gRationale:
Clozapine, gan gantipsychotic, gcan gcause gdangerous gWBC gsuppression. gPatients grequire
groutine gCBC gmonitoring.




Question g8

Which gmedication gshould gbe gadministered gbefore gmeals gto gprotect gthe gstomach
glining?


A. gOmeprazole
B. gSucralfate g✅
C. gRanitidine
D. gAluminum ghydroxide

✅ gCorrect gAnswer: gB. gSucralfate

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