NSG6005 ADVANCED PHARMACOLOGY
FINAL EXAM. ALL CHAPTERS COVERED
2025
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy? - (answers)To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? -
(answers)Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with? - (answers)Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? -
(answers)Aldosterone antagonist
Heparin exerts its therapeutic action by what? - (answers)Upregulating the
activity of one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during
an anaphylactic reaction. - (answers)Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - (answers)Photo-therapy and
topical corticosteroids
, 2
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension? - (answers)Thiazide diuretics
What is the effect of cardiac glycosides? - (answers)Digitalis glycosides have a
negative chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
(answers)Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for
available beta-receptor sites? - (answers)Atenolol (Tenormin)
What type of action does nitrates have on the body? - (answers)Reduction in
systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for
patients with known coronary artery disease? - (answers)100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - (answers)Depressing
phase 4 depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease? -
(answers)Anti-thyroid drugs.