Neurons rely on ____ for protection, metabolic
support and insulation
Glial cells
Which of the following factors does NOT affect the
pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action
Drug action
The sac-like structures in the presynaptic terminal
are called ______ and are filled with
_______
Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli,
psychoactive drugs can trigger longlasting changes in
neuronal connectivity. Collectively, these changes
are termed
Synaptic plasticity
Axonal transport of proteins occurs along a track
formed by
Microtubules
Reduce the rate of cell firing
When activated, somatodendritic autoreceptors
,Psychopharmacology Final Exa m
If a substance is a neurotransmitter, stimulation of Direct application of the proposed substance to the postsynaptic cell
the presynaptic cell should have the same effect as
In order for a substance to be considered a Vesicles containing the substance should move down the axon with the action
neurotransmitter it must meet several criteria. potentials when the neuron is stimulated
Which of the following is NOT considered a criterion
for neurotransmitter status?
A) A synthetic mechanism should be presentin the
presynaptic cell
B) Vesicles containing the substance shouldmove
down the axon with the action potentials when the
neuron is stimulated C) Receptors for the proposed
substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be
present
The Na+/K+ pump helps to maintain the ______ by Resting membrane potential
moving three Na+ ions in and two K+ ions out of the
cell
Psychopharmacology Final Exam
,Activating a metabotropic receptor can
result in all of the following except for A)
Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression
Changes in gene expression
Drug metabolism mostly occurs in the ____ and
usually makes a drug more _____ soluble.
Liver; Water
The ____ is best described as a result of the
selective permeability of the neuronal
membrane and the uneven distribution of
ions inside and outside the cell.
Resting membrane potential
After drug administration has occurred, the amount
of drug in the blood that is free to bind at specific
target sites is/are referred to as
Bioavailability
In the dose-response curve, a decrease in To the right
potency is indicated by a shift
Psychopharmacology Final Exa m
, _____ refer(s) to specific molecular changes that Drug action; drug effects
occur when a drug binds to a particular target site or
receptor, while ______ are the resulting widespread
alterations in function.
Selective blockade of terminal autoreceptors for DA Increase in neurotransmitter release
would lead to a(n)
Prior to neurotransmitter release, vesicles are Priming, exocytosis.
transported to specialized regions of the presynaptic
terminal called _____ zones, where they bind to the
terminal in a process known as ___________.
Steroid hormones bind to ______ receptors, which Intracellular; Transcription factors
act as ______ when activated, and regulate gene
expression
The absorption of a drug depends on all of the Body temperature
following except
A) Lipid solubility
B) Ionization
C) Body temperature
D) The concentration of the drug
support and insulation
Glial cells
Which of the following factors does NOT affect the
pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action
Drug action
The sac-like structures in the presynaptic terminal
are called ______ and are filled with
_______
Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli,
psychoactive drugs can trigger longlasting changes in
neuronal connectivity. Collectively, these changes
are termed
Synaptic plasticity
Axonal transport of proteins occurs along a track
formed by
Microtubules
Reduce the rate of cell firing
When activated, somatodendritic autoreceptors
,Psychopharmacology Final Exa m
If a substance is a neurotransmitter, stimulation of Direct application of the proposed substance to the postsynaptic cell
the presynaptic cell should have the same effect as
In order for a substance to be considered a Vesicles containing the substance should move down the axon with the action
neurotransmitter it must meet several criteria. potentials when the neuron is stimulated
Which of the following is NOT considered a criterion
for neurotransmitter status?
A) A synthetic mechanism should be presentin the
presynaptic cell
B) Vesicles containing the substance shouldmove
down the axon with the action potentials when the
neuron is stimulated C) Receptors for the proposed
substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be
present
The Na+/K+ pump helps to maintain the ______ by Resting membrane potential
moving three Na+ ions in and two K+ ions out of the
cell
Psychopharmacology Final Exam
,Activating a metabotropic receptor can
result in all of the following except for A)
Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression
Changes in gene expression
Drug metabolism mostly occurs in the ____ and
usually makes a drug more _____ soluble.
Liver; Water
The ____ is best described as a result of the
selective permeability of the neuronal
membrane and the uneven distribution of
ions inside and outside the cell.
Resting membrane potential
After drug administration has occurred, the amount
of drug in the blood that is free to bind at specific
target sites is/are referred to as
Bioavailability
In the dose-response curve, a decrease in To the right
potency is indicated by a shift
Psychopharmacology Final Exa m
, _____ refer(s) to specific molecular changes that Drug action; drug effects
occur when a drug binds to a particular target site or
receptor, while ______ are the resulting widespread
alterations in function.
Selective blockade of terminal autoreceptors for DA Increase in neurotransmitter release
would lead to a(n)
Prior to neurotransmitter release, vesicles are Priming, exocytosis.
transported to specialized regions of the presynaptic
terminal called _____ zones, where they bind to the
terminal in a process known as ___________.
Steroid hormones bind to ______ receptors, which Intracellular; Transcription factors
act as ______ when activated, and regulate gene
expression
The absorption of a drug depends on all of the Body temperature
following except
A) Lipid solubility
B) Ionization
C) Body temperature
D) The concentration of the drug
