NRNP 6566 Advanced Care
of Adults in Acute Settings I
– Week 11 Knowledge
Check
Instructions
• Read each question carefully.
• Select the best possible answer from the given options.
• Review rationales to understand why the correct choice is
best.
• UseSectio
this knowledge check to reinforce your learning for
Week 11.
, 2
Question 1
A 62-year-old male presents to the ICU with acute respiratory distress syndrome
(ARDS) secondary to pneumonia. According to the 2025 Berlin Definition and
ATS guidelines, which ventilator strategy is most appropriate to optimize
oxygenation while minimizing lung injury?
A. High-frequency oscillatory ventilation (HFOV)
B. Low tidal volume ventilation (6 mL/kg ideal body weight)
C. Pressure control ventilation with PEEP of 5 cm H₂O
D. Volume control ventilation with tidal volume of 10 mL/kg
Answer: B. Low tidal volume ventilation (6 mL/kg ideal body weight)
Rationale: The 2025 ATS guidelines and Berlin Definition emphasize lung-
protective ventilation for ARDS, recommending low tidal volume ventilation (6
mL/kg ideal body weight) to minimize ventilator-induced lung injury (VILI) while
maintaining adequate oxygenation. HFOV (A) is no longer first-line due to lack of
mortality benefit in recent trials. Low PEEP (C) is insufficient for severe ARDS,
where higher PEEP is often needed. High tidal volumes (D) increase VILI risk and
are contraindicated.
Question 2
A 55-year-old female with septic shock is admitted to the ICU. Per the 2026
Surviving Sepsis Campaign guidelines, what is the recommended initial fluid
resuscitation strategy?
A. 500 mL crystalloid bolus over 60 minutes
B. 30 mL/kg crystalloid bolus within the first 3 hours
C. Albumin 5% infusion at 10 mL/kg over 6 hours
D. Balanced crystalloid infusion titrated to urine output only
Answer: B. 30 mL/kg crystalloid bolus within the first 3 hours
Rationale: The 2026 Surviving Sepsis guidelines recommend rapid administration
of 30 mL/kg of crystalloid (e.g., lactated Ringer’s) within 3 hours for septic shock