University.
1/
12
, MB 351 Exam 1 Review – North Carolina State
University.
1. Robert Hooke first to describe microbes
2. Antoni van first to describe bacteria ("animalcules")
Leeuwenhoe
k
3. Louis Pasteur helped disprove theory of spontaneous generation with swan-necked
flask,
invented pasteurization
4. Spontaneous theory that microorganisms arose spontaneously from seeds or
Gen- eration
germs in the air, based on observations of meat rotting
5. Francisco Redi kept meat in sealed and unsealed containers, showed that flies did not
sponta-
neously generate
6. John Needham proponent of Spontaneous Generation - boiled flasks, left one open
and capped
the other after it cooled, which led to microbial growth in both
7. Lazzaro boiled a sealed flask, which resulted in no growth - said the "vital force"
Spallan- zani
of air was killed
8. Edward Jenner "father of vaccinology," made a vaccine for smallpox
9. Ignaz Semmelweis encouraged hand washing in between patients, helped stop
childbed fever
10. Joseph Lister disinfecting surgical instruments and wounds helped decrease
infections
11. Robert Koch link between microbes and disease
12. Koch's Postulates 1) suspected pathogen must be present in all cases of disease, absent
from
2/
12