Module 7: Immune System
Pathophysiology Exam 2026 Questions
and Answers
Which disorder is associated with a type III hypersensitivity mechanism of injury?
- Systemic lupus erythematosus
- Graves disease
- Erythroblastosis fetalis
- Seasonal allergic rhinitis - Correct answer-Systemic lupus erythematosus
Systemic lupus erythematosus is a type III hypersensitivity disorder. Type III
hypersensitivity is characterized by antigen-antibody complex deposition into
tissues, with consequent activation of complement and a subsequent self-sustaining
inflammatory reaction. Graves disease and erythroblastosis fetalis are type II
hypersensitivity reactions. Seasonal allergic rhinitis is a type I hypersensitivity
reaction.
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,The most common primary immune deficiency that affects only B cells is
- DiGeorge.
- Bruton agammaglobulinemia.
- Wiskott-Aldrich.
- selective IgA - Correct answer-selective IgA
The most common B-cell primary immunodeficiency disorder is selective IgA
deficiency. This disorder affects 1:2000 persons. DiGeorge is a T-cell primary
immune deficiency. Bruton agammaglobulinemia is not the most common primary
immune deficiency affecting B cells; frequency of disease is 1:250,000 males.
Females are carriers. Wiskott-Aldrich affects both T cells and B cells.
Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions.
T/F - Correct answer-False
Seasonal allergic rhinitis is most involved in type I hypersensitivity reactions.
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, Anaphylaxis may occur in certain hypersensitivity reactions, including type (Select
all that apply.)
- I.
- II.
- III.
- IV. - Correct answer-- I.
- II.
A child with a history of recent strep throat infection develops glomerulonephritis.
This is most likely a type _____ hypersensitivity reaction.
- I.
- II.
- III.
- IV. - Correct answer-III
Immune complex glomerulonephritis (an inflammatory renal disorder) is an
example of a type III hypersensitivity reaction. The circulating immune complex is
then deposited in the glomerular capillary wall and mesangium.
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Pathophysiology Exam 2026 Questions
and Answers
Which disorder is associated with a type III hypersensitivity mechanism of injury?
- Systemic lupus erythematosus
- Graves disease
- Erythroblastosis fetalis
- Seasonal allergic rhinitis - Correct answer-Systemic lupus erythematosus
Systemic lupus erythematosus is a type III hypersensitivity disorder. Type III
hypersensitivity is characterized by antigen-antibody complex deposition into
tissues, with consequent activation of complement and a subsequent self-sustaining
inflammatory reaction. Graves disease and erythroblastosis fetalis are type II
hypersensitivity reactions. Seasonal allergic rhinitis is a type I hypersensitivity
reaction.
©COPYRIGHT 2025, ALL RIGHTS RESERVE 1
,The most common primary immune deficiency that affects only B cells is
- DiGeorge.
- Bruton agammaglobulinemia.
- Wiskott-Aldrich.
- selective IgA - Correct answer-selective IgA
The most common B-cell primary immunodeficiency disorder is selective IgA
deficiency. This disorder affects 1:2000 persons. DiGeorge is a T-cell primary
immune deficiency. Bruton agammaglobulinemia is not the most common primary
immune deficiency affecting B cells; frequency of disease is 1:250,000 males.
Females are carriers. Wiskott-Aldrich affects both T cells and B cells.
Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions.
T/F - Correct answer-False
Seasonal allergic rhinitis is most involved in type I hypersensitivity reactions.
©COPYRIGHT 2025, ALL RIGHTS RESERVE 2
, Anaphylaxis may occur in certain hypersensitivity reactions, including type (Select
all that apply.)
- I.
- II.
- III.
- IV. - Correct answer-- I.
- II.
A child with a history of recent strep throat infection develops glomerulonephritis.
This is most likely a type _____ hypersensitivity reaction.
- I.
- II.
- III.
- IV. - Correct answer-III
Immune complex glomerulonephritis (an inflammatory renal disorder) is an
example of a type III hypersensitivity reaction. The circulating immune complex is
then deposited in the glomerular capillary wall and mesangium.
©COPYRIGHT 2025, ALL RIGHTS RESERVE 3
